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Gene: Arl1 MGI:99436

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
ADP-ribosylation factor-like 1
Synonyms:
2310008D22Rik

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Arl1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Arl1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Arl1.

There are 4 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout. FASEB journal : official publication of the Federation of American Societies for Experimental Biology (November 2023) Arl15em1(IMPC)H Arl15tm1a(EUCOMM)Wtsi Arl15tm1b(EUCOMM)Wtsi 37773757
ARL13B regulates Sonic hedgehog signaling from outside primary cilia. eLife (March 2020) Arl13btm1c(EUCOMM)Wtsi PMC7075693
Deletion of ADP Ribosylation Factor-Like GTPase 13B Leads to Kidney Cysts. Journal of the American Society of Nephrology : JASN (May 2016) Arl13btm1c(EUCOMM)Wtsi Arl13btm1a(EUCOMM)Wtsi PMC5118478
Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. PLoS genetics (February 2016) Arl10tm1(KOMP)Vlcg PMC4739719

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All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Arl1tm2a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Arl1tm2e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Arl1tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Arl1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Arl1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

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