Gene: Arf4

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Arf4tm1b(KOMP)Wtsi HOM E9.5 0.00
embryonic growth retardation Arf4tm1b(KOMP)Wtsi HET E9.5 0.00
preweaning lethality, complete penetrance Arf4tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal embryo size Arf4tm1b(KOMP)Wtsi HET E9.5 0.00
embryonic lethality prior to tooth bud stage Arf4tm1b(KOMP)Wtsi HOM E12.5 0.00
embryonic growth retardation Arf4tm1b(KOMP)Wtsi HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No  (2/2)  Section images
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 5  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 5  (1/504) N/A
Embryo 5  (1/505)  (2/5) N/A
Eye 5  (1/504) N/A
Foot 5  (1/504) N/A
Forebrain 5  (1/504) N/A
Forelimb 5  (1/504) N/A
Gut 2  (1/56)  (2/2) N/A
Hand 5  (1/503) N/A
Head 5  (5/504) N/A
Heart 5  (1/504)  (2/5) N/A
Hindbrain 5  (6/504) N/A
Hindlimb 5  (1/503) N/A
Liver 5  (1/504) N/A
Lung 5  (1/500)  (2/5) N/A
Mandibular process 5  (1/504) N/A
Maxillary process 5  (1/504) N/A
Midbrain 5  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 5  (1/504) N/A
2  (7/37)  (2/2) N/A
Skeleton 2  (1/70) N/A
Skin 5  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 5  (1/504) N/A
Tail somite 5  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
10 Images
Embryo LacZ: LacZ images wholemount
20 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Gross Morphology Embryo E9.5
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Arf4tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Arf4tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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