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Gene: Wnt1

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Name
wingless-type MMTV integration site family, member 1
MGI ID
MGI:98953
Synonyms
Int-1 Wnt-1
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (10) Measurements chart (209) All data table (509)
Expression & images (102) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Wnt1tm1b(EUCOMM)Wtsi HET E12.5 0.00
increased circulating cholesterol level Wnt1tm1b(EUCOMM)Wtsi HET Early adult 7.15×10-06
increased circulating serum albumin level Wnt1tm1b(EUCOMM)Wtsi HET Early adult 2.06×10-07
abnormal eye morphology Wnt1tm1b(EUCOMM)Wtsi HET E12.5 0.00
preweaning lethality, incomplete penetrance Wnt1tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
abnormal placenta size Wnt1tm1b(EUCOMM)Wtsi HET E12.5 0.00
increased circulating calcium level Wnt1tm1b(EUCOMM)Wtsi HET Early adult 3.14×10-07
abnormal limb bud morphology Wnt1tm1b(EUCOMM)Wtsi HET E12.5 0.00
increased circulating total protein level Wnt1tm1b(EUCOMM)Wtsi HET Early adult 3.10×10-07
increased circulating creatinine level Wnt1tm1b(EUCOMM)Wtsi HET Early adult 7.39×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (3/590) N/A
Aorta 1 No  (1/590) N/A
Blood 1 No N/A
Bone marrow 1 No N/A
Brain 1 No  (3/590) N/A
Brainstem 1 No  (2/590) N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/377) N/A
Cerebellum 1 No  (3/590) N/A
Cerebral cortex 1 No  (2/590) N/A
Chest bone 1 No N/A
Colon 1 No  (12/127) N/A
Diaphragm 1 No N/A
Duodenum 1 No  (2/127) N/A
Epididymis 1 No  (18/134)  (1/1)  Section images
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Gonadal fat pad 1 No N/A
Harderian gland 1 No N/A
Heart 1 No  (1/590) N/A
Hindlimb 1 No N/A
Hippocampus 1 No  (3/590) N/A
Hypothalamus 1 No  (2/590) N/A
Ileum 1 No  (14/127) N/A
Jejunum 1 No  (6/127) N/A
Kidney 1 No  (20/590) N/A
Large intestine 1 No  (10/590) N/A
Liver 1 No N/A
Lower urinary tract 1 No  (1/590) N/A
Lung 1 No  (1/590) N/A
Lymph node 1 No N/A
Mammary gland 1 No N/A
Mesenteric adipose tissue 1 No N/A
Mesenteric lymph node 1 No N/A
Midbrain 1 No N/A
Olfactory lobe 1 No  (2/590) N/A
Ovary 1 No  (1/590) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/590) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No N/A
Penis 1 No N/A
Peripheral nervous system 1 No  (1/590) N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/590) N/A
Prostate gland 1 No  (12/590) N/A
Quadriceps 1 No N/A
Sciatic nerve 1 No N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/590) N/A
Spinal cord 1 No  (2/590) N/A
Spleen 1 No  (2/590) N/A
Stomach 1 No  (13/590) N/A
Stomach pyloric region 1 No N/A
Striatum 1 No  (3/590) N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/132) N/A
Testis 1 No  (5/590)  (1/1)  Section images
Thymus 1 No N/A
Thyroid gland 1 No  (16/590) N/A
Tongue 1 No  (5/127) N/A
Trachea 1 No  (2/590) N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388)  (1/1)  Section images
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
LacZ Wholemount Images
LacZ Section Images
postnatal mouse (4)
Epididymis expression
MA:0000397
reproductive system (4)
Epididymis expression
MA:0000397
trunk (4)
Epididymis expression
MA:0000397
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/65) N/A
Brain 2  (6/506)  (2/2) N/A
Central nervous system ganglion 2  (1/74) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507) Image Only N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506)  (2/2) N/A
Forelimb 2  (1/506) N/A
Gut 2  (1/60) N/A
Hand 2  (1/506) N/A
Head 2  (5/506) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506)  (2/2) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506)  (2/2) N/A
Nose 2  (1/76) N/A
Oral cavity 2  (1/504) N/A
Skeleton 2  (1/76) N/A
Skin 2  (1/506) N/A
Spinal cord 2  (1/73)  (2/2) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A
Trachea 2  (1/60) N/A
Urinary system 2  (1/60) N/A

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Adult LacZ: LacZ Images Section
4 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Wnt1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Wnt1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Wnt1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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