Gene: Thbs1

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal lung morphology Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal heart morphology Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal liver morphology Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased circulating insulin level Thbs1tm1.1(KOMP)Vlcg HOM Early adult 1.22×10-05
enlarged heart Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
increased bone mineral content Thbs1tm1.1(KOMP)Vlcg HOM Early adult 8.35×10-05
decreased body length Thbs1tm1.1(KOMP)Vlcg HOM Early adult 1.90×10-05

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584)  (1/1)  Section images
Aorta 1 No  (1/1)  Section images
Blood 1 No  (1/1)  Section images
Bone marrow 1 No  (1/1)  Section images
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/379)  (1/1)  Section images
Cerebellum 1 No  (1/1)  Section images
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1)  Section images
Diaphragm 1 No  (1/1)  Section images
Duodenum 1 No  (2/127)  (1/1)  Section images
Epididymis 1 No  (18/134) N/A
Esophagus 1 No  (7/415)  (1/1)  Section images
Eye 1 No  (1/1)  Section images
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1)  Section images
Harderian gland 1 No  (1/1)  Section images
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Ileum 1 No  (14/127)  (1/1)  Section images
Jejunum 1 No  (6/127) N/A
Kidney 1 No  (18/584)  (1/1)  Section images
Large intestine 1 No  (10/584) N/A
Liver 1 No  (1/1)  Section images
Lower urinary tract 1 No N/A
Lung 1 No  (1/1)  Section images
Lymph node 1 No N/A
Mammary gland 1 No  (1/1)  Section images
Mesenteric adipose tissue 1 No  Section images
Mesenteric lymph node 1 No  (1/1)  Section images
Midbrain 1 No  (1/1)  Section images
Olfactory lobe 1 No N/A
Ovary 1 No  (1/584)  (1/1)  Section images
Oviduct 1 No  (1/1)  Section images
Pancreas 1 No  (5/584)  (1/1)  Section images
Parathyroid gland 1 No  (1/1)  Section images
Parotid gland 1 No  (1/1)  Section images
Penis 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Quadriceps 1 No  (1/1)  Section images
Sciatic nerve 1 No  (1/1)  Section images
Skeletal muscle 1 No N/A
Skin 1 No  (1/1)  Section images
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No  (1/1)  Section images
Spleen 1 No  (2/584)  (1/1)  Section images
Stomach 1 No  (12/584)  (1/1)  Section images
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No  (1/1)  Section images
Submandibular gland 1 No  (2/132)  (1/1)  Section images
Testis 1 No  (2/584) N/A
Thymus 1 No  (1/1)  Section images
Thyroid gland 1 No  (15/584)  (1/1)  Section images
Tongue 1 No  (5/127)  (1/1)  Section images
Trachea 1 No N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No  (1/1)  Section images
Uterus 1 No  (1/1)  Section images
Vagina 1 No  (1/1)  Section images
Vas deferens 1 No  (15/388) N/A
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
100 Images
X-ray: XRay Images Whole Body Dorso Ventral
39 Images
X-ray: XRay Images Whole Body Lateral Orientation
21 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Thbs1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Thbs1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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