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Genes Phenotypes

Gene: Thbs1

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Name
thrombospondin 1
MGI ID
MGI:98737
Synonyms
TSP1 TSP-1 Thbs-1 tbsp1
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (194) All data table (382)
Expression & images (73) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased bone mineral content Thbs1tm1.1(KOMP)Vlcg HOM Early adult 1.73×10-05
enlarged heart Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal heart morphology Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal lung morphology Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal liver morphology Thbs1tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased circulating insulin level Thbs1tm1.1(KOMP)Vlcg HOM Early adult 3.90×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (3/590)  (1/1)  Section images
Aorta 1 No  (1/590)  (1/1)  Section images
Blood 1 No  (1/1)  Section images
Bone marrow 1 No  (1/1)  Section images
Brain 1 No  (3/590) N/A
Brainstem 1 No  (2/590) N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/377)  (1/1)  Section images
Cerebellum 1 No  (3/590)  (1/1)  Section images
Cerebral cortex 1 No  (2/590) N/A
Chest bone 1 No N/A
Colon 1 No  (12/127)  (1/1)  Section images
Diaphragm 1 No  (1/1)  Section images
Duodenum 1 No  (2/127)  (1/1)  Section images
Epididymis 1 No  (18/134) N/A
Esophagus 1 No  (7/415)  (1/1)  Section images
Eye 1 No  (1/1)  Section images
Gall bladder 1 No N/A
Gonadal fat pad 1 No  (1/1)  Section images
Harderian gland 1 No  (1/1)  Section images
Heart 1 No  (1/590) N/A
Hindlimb 1 No N/A
Hippocampus 1 No  (3/590) N/A
Hypothalamus 1 No  (2/590) N/A
Ileum 1 No  (14/127)  (1/1)  Section images
Jejunum 1 No  (6/127) N/A
Kidney 1 No  (20/590)  (1/1)  Section images
Large intestine 1 No  (10/590) N/A
Liver 1 No  (1/1)  Section images
Lower urinary tract 1 No  (1/590) N/A
Lung 1 No  (1/590)  (1/1)  Section images
Lymph node 1 No N/A
Mammary gland 1 No  (1/1)  Section images
Mesenteric adipose tissue 1 No  Section images
Mesenteric lymph node 1 No  (1/1)  Section images
Midbrain 1 No  (1/1)  Section images
Olfactory lobe 1 No  (2/590) N/A
Ovary 1 No  (1/590)  (1/1)  Section images
Oviduct 1 No  (1/1)  Section images
Pancreas 1 No  (5/590)  (1/1)  Section images
Parathyroid gland 1 No  (1/1)  Section images
Parotid gland 1 No  (1/1)  Section images
Penis 1 No N/A
Peripheral nervous system 1 No  (1/590) N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No  (1/590) N/A
Prostate gland 1 No  (12/590) N/A
Quadriceps 1 No  (1/1)  Section images
Sciatic nerve 1 No  (1/1)  Section images
Skeletal muscle 1 No N/A
Skin 1 No  (1/1)  Section images
Small intestine 1 No  (9/590) N/A
Spinal cord 1 No  (2/590)  (1/1)  Section images
Spleen 1 No  (2/590)  (1/1)  Section images
Stomach 1 No  (13/590)  (1/1)  Section images
Stomach pyloric region 1 No N/A
Striatum 1 No  (3/590) N/A
Sublingual gland 1 No  (1/1)  Section images
Submandibular gland 1 No  (2/132)  (1/1)  Section images
Testis 1 No  (5/590) N/A
Thymus 1 No  (1/1)  Section images
Thyroid gland 1 No  (16/590)  (1/1)  Section images
Tongue 1 No  (5/127)  (1/1)  Section images
Trachea 1 No  (2/590) N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No  (1/1)  Section images
Uterus 1 No  (1/1)  Section images
Vagina 1 No  (1/1)  Section images
Vas deferens 1 No  (15/388) N/A
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (12)
adipose tissue (4)
Gonadal fat pad expression
MA:0002547
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (26)
Cecum expression
MA:0000334
endocrine system (6)
Adrenal gland expression
MA:0000116
exocrine system (8)
Mammary gland expression
MA:0000145
immune system (11)
Bone Marrow expression
MA:0000134
integumental system (4)
Mammary gland expression
MA:0000145
limb (1)
Sciatic nerve expression
MA:0001172
musculoskeletal system (7)
Bone Marrow expression
MA:0000134
nervous system (5)
Cerebellum expression
MA:0000198
postnatal mouse (88)
Adrenal gland expression
MA:0000116
reproductive system (8)
Ovary expression
MA:0000384
respiratory system (13)
Diaphragm expression
MA:0001904
sensory organ (8)
Eye expression
MA:0000261
set of connective tissues (4)
Gonadal fat pad expression
MA:0002547
trunk (49)
Adrenal gland expression
MA:0000116
urinary system (7)
Kidney expression
MA:0000368
No Embryo expression data was found for this gene.

 Associated Images

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Adult LacZ: LacZ Images Section
100 Images
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X-ray: XRay Images Whole Body Dorso Ventral
20 Images
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X-ray: XRay Images Whole Body Lateral Orientation
20 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Thbs1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Thbs1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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