Gene: Ift88

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Name
intraflagellar transport 88
MGI ID
MGI:98715
Synonyms
Tg737 orpk Oak Ridge polycystic kidneys polaris fxo IFT88 TgN737Rpw Tg737Rpw Ttc10
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Ift88tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HET E9.5 0.00
abnormal embryo turning Ift88tm1.1(KOMP)Vlcg HET E9.5 0.00
increased thigmotaxis Ift88tm1.1(KOMP)Vlcg HET Early adult 2.35×10-05
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HOM E12.5 0.00
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HET E12.5 0.00
abnormal embryo turning Ift88tm1.1(KOMP)Vlcg HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2)  Section images
Aorta 2 No  (1/589)  (2/2)  Section images
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (3/589)  (2/2)  Section images
Brainstem 2 No  (2/589)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (3/589)  (2/2)  Section images
Cerebral cortex 2 No  (2/589)  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (1/2)  Section images
Eye 2 No  (1/2)  Section images
Heart 2 No  (1/589)  (2/2)  Section images
Hippocampus 2 No  (3/589)  (2/2)  Section images
Hypothalamus 2 No  (2/589)  (2/2)  Section images
Kidney 2 No  (20/589)  (2/2)  Section images
Large intestine 2 No  (10/589) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589)  (2/2)  Section images
Lymph node 2 No N/A
Main olfactory bulb 2 No  (2/2)  Section images
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/589)  (2/2)  Section images
Ovary 2 No  (1/589)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/589)  (1/2)  Section images
Peripheral nervous system 2 No  (1/589)  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (1/2)  Section images
Prostate gland 2 No  (12/589) N/A
Quadriceps 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589)  (2/2)  Section images
Spleen 2 No  (2/589)  (2/2)  Section images
Stomach 2 No  (13/589) N/A
Striatum 2 No  (3/589) N/A
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (5/589)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589)  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vagina 2 No N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506)  (1/1) N/A
Dorsal root ganglion 1  (1/61) Image Only N/A
Ear 1  (1/506) N/A
Embryo 1  (1/507)  (1/1)  Wholemount images
Eye 1  (1/506) N/A
Foot 1  (1/506)  (1/1) N/A
Forebrain 1  (1/506)  (1/1) N/A
Forelimb 1  (1/506)  (1/1) N/A
Fronto-nasal process 1  (1/62) Image Only N/A
Hand 1  (1/505)  (1/1) N/A
Head 1  (5/506)  (1/1) N/A
Heart 1  (1/506) N/A
Hindbrain 1  (6/506)  (1/1) N/A
Hindlimb 1  (1/505)  (1/1) N/A
Liver 1  (1/506) N/A
Lung 1  (1/502) Image Only N/A
Mandibular process 1  (1/506)  (1/1) N/A
Maxillary process 1  (1/506)  (1/1) N/A
Midbrain 1  (1/506) Image Only N/A
Nose 1  (1/74)  (1/1) N/A
Oral cavity 1  (1/506) Image Only N/A
Skin 1  (1/506) Image Only N/A
Spinal cord 1  (1/73) Image Only N/A
Tail 1  (1/506) N/A
Tail somite 1  (1/506) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
4 Images
Adult LacZ: LacZ Images Section
30 Images
Sleep Wake: Wake state (bmp file)
17 Images
X-ray: XRay Images Whole Body Lateral Orientation
1 Images
Combined SHIRPA and Dysmorphology
3 Images
Eye Morphology: Images Slit Lamp
2 Images
X-ray: XRay Images Skull Lateral Orientation
1 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
1 Images
X-ray: XRay Images Whole Body Dorso Ventral
1 Images
X-ray: XRay Images Forepaw
1 Images

 Disease Models

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MGI Allele Allele Type Produced
Ift88tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Ift88tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ift88tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells