Gene: Ift88

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Name
intraflagellar transport 88
MGI ID
MGI:98715
Synonyms
Tg737 Oak Ridge polycystic kidneys orpk polaris IFT88 fxo TgN737Rpw Tg737Rpw Ttc10
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Ift88tm1.1(KOMP)Vlcg HET Early adult 1.06×10-05
preweaning lethality, complete penetrance Ift88tm1.1(KOMP)Vlcg HOM   Early adult 0.00
abnormal embryo turning Ift88tm1.1(KOMP)Vlcg HOM E9.5 0.00
increased thigmotaxis Ift88tm1.1(KOMP)Vlcg HET Early adult 2.15×10-05
embryonic growth retardation Ift88tm1.1(KOMP)Vlcg HOM E9.5 0.00
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HOM E9.5 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583)  (2/2)  Section images
Aorta 2 No  (1/583)  (2/2)  Section images
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583)  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2)  Section images
Cerebellum 2 No  (3/583)  (2/2)  Section images
Cerebral cortex 2 No  (2/583)  (2/2)  Section images
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407)  (1/2)  Section images
Eye 2 No  (1/2)  Section images
Heart 2 No  (2/583)  (2/2)  Section images
Hippocampus 2 No  (3/583)  (2/2)  Section images
Hypothalamus 2 No  (2/583)  (2/2)  Section images
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583)  (2/2)  Section images
Lymph node 2 No  (1/583) N/A
Main olfactory bulb 2 No  (2/2)  Section images
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (2/2)  Section images
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/583)  (1/2)  Section images
Peripheral nervous system 2 No  (2/583)  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (1/2)  Section images
Prostate gland 2 No  (12/583) N/A
Quadriceps 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583)  (2/2)  Section images
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Submandibular gland 2 No  (2/130)  (2/2)  Section images
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/583)  (2/2) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583)  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vagina 2 No N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/505)  (1/1) N/A
1  (1/60) Image Only N/A
1  (1/505) N/A
1  (1/506)  (1/1)  Wholemount images
1  (1/505) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/61) Image Only N/A
1  (1/505)  (1/1) N/A
1  (5/505)  (1/1) N/A
1  (1/505) N/A
1  (6/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/503) N/A
1  (1/503) Image Only N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505) Image Only N/A
1  (1/75)  (1/1) N/A
1  (1/503) Image Only N/A
1  (1/505) Image Only N/A
1  (1/72) Image Only N/A
1  (1/505) N/A
1  (1/505) N/A

 Associated Images

X-ray: XRay Images Forepaw
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
Original Image
Adult LacZ: LacZ Images Section
30 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
Combined SHIRPA and Dysmorphology
3 Images
Eye Morphology: Images Slit Lamp
2 Images
Embryo LacZ: LacZ images wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
2 Images

 Disease Models

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MGI Allele Allele Type Produced
Ift88tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ift88tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Ift88tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells