Gene: Ift88

Name
intraflagellar transport 88
MGI ID
MGI:98715
Synonyms
Tg737Rpw TgN737Rpw Ttc10 IFT88 Tg737 fxo polaris Oak Ridge polycystic kidneys orpk
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Ift88tm1.1(KOMP)Vlcg HET postnatal 1.47×10-05
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
abnormal embryo turning Ift88tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
preweaning lethality, complete penetrance Ift88tm1.1(KOMP)Vlcg HOM n/a 0.00
embryonic growth retardation Ift88tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
hyperactivity Ift88tm1.1(KOMP)Vlcg HET postnatal 1.76×10-05
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HET embryonic day 12.5 0.00
abnormal embryo size Ift88tm1.1(KOMP)Vlcg HOM embryonic day 9.5 0.00
abnormal embryo turning Ift88tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
embryonic growth retardation Ift88tm1.1(KOMP)Vlcg HET embryonic day 9.5 0.00
hypoactivity Ift88tm1.1(KOMP)Vlcg HET postnatal 1.76×10-05

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Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Bone 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (1/2)  Section images
Eye 2 No  (1/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Main olfactory bulb 2 No  (2/2)  Section images
Mammary gland 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (1/2)  Section images
Peripheral nervous system 2 No  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2)  Section images
Prostate gland 2 No  (12/584) N/A
Quadriceps 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vagina 2 No N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (1/1) N/A
Dorsal root ganglion 1  (1/47) Image Only N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (1/1) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485)  (1/1) N/A
Forebrain 1  (1/485)  (1/1) N/A
Forelimb 1  (1/485)  (1/1) N/A
Fronto-nasal process 1  (1/48) Image Only N/A
Hand 1  (1/485)  (1/1) N/A
Head 1  (5/485)  (1/1) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485)  (1/1) N/A
Hindlimb 1  (1/485)  (1/1) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) Image Only N/A
Mandibular process 1  (1/485)  (1/1) N/A
Maxillary process 1  (1/485)  (1/1) N/A
Midbrain 1  (1/485) Image Only N/A
Nose 1  (1/51)  (1/1) N/A
Oral cavity 1  (1/485) Image Only N/A
Skin 1  (1/485) Image Only N/A
Spinal cord 1  (1/50) Image Only N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
11 Images
Original Image
Adult LacZ: LacZ Images Section
30 Images
X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Forepaw
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Combined SHIRPA and Dysmorphology
3 Images
Sleep Wake: Wake state (bmp file)
1 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Ift88tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ift88tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Ift88tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice