Dntt | deoxynucleotidyltransferase, terminal
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
16 No significant impact
6 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
increased circulating sodium level | 1 supporting dataset | Dntttm2b(KOMP)Wtsi | homozygote | Early adult | 2.51x10-7 | ||
increased circulating HDL cholesterol level | 1 supporting dataset | Dntttm2b(KOMP)Wtsi | homozygote | Early adult | 8.09x10-9 | ||
increased circulating cholesterol level | 1 supporting dataset | Dntttm2b(KOMP)Wtsi | homozygote | Early adult | 1.58x10-7 | ||
increased coping response | 1 supporting dataset | Dntttm2b(KOMP)Wtsi | homozygote | Early adult | 7.55x10-5 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | 0% (0/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | 0% (0/2) | 0.41% (2/491) |
epididymis | heterozygote | n/a | 0% (0/1) | 87.5% (21/24) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
No external links available for Dntt.
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Dntttm119376(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Dntttm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
Dntttm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Dntttm2b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Dntttm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |