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Genes Phenotypes Help, News, Blog

Gene: Snai1 MGI:98330

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
snail family zinc finger 1
Synonyms:
Snail1,  Sna1,  Snail,  Sna

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IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Snai1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.
No human diseases associated to this gene by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Snai1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Snai1.

There are 5 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
Snail/Slug-YAP/TAZ complexes cooperatively regulate mesenchymal stem cell function and bone formation. Cell cycle (Georgetown, Tex.) (January 2017) Snai1tm1(KOMP)Vlcg PMC5351930
Snail1-dependent p53 repression regulates expansion and activity of tumour-initiating cells in breast cancer. Nature cell biology (October 2016) Snai1tm1(KOMP)Vlcg PMC6038146
Snail/Slug binding interactions with YAP/TAZ control skeletal stem cell self-renewal and differentiation. Nature cell biology (August 2016) Snai1tm1(KOMP)Vlcg PMC5007193
A Snail1/Notch1 signalling axis controls embryonic vascular development. Nature communications (June 2014) Snai1tm1(KOMP)Vlcg PMC4052376
Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment. Nature communications (January 2014) Snai1tm1(KOMP)Vlcg PMC4115678

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Snai1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Snai1tm464263(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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