Gene: Shmt1

Name
serine hydroxymethyltransferase 1 (soluble)
MGI ID
MGI:98299
Synonyms
mshmt Shmt mshmt1 mshmt2
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Alanine aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.181 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / LVPWd HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.207 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Bulging eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Creatinine HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.723 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Iris/Pupil HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Mean cell hemoglobin concentration HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.646 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Mean platelet volume HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00571 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.314 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Eosinophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.699 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / LVAWs HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0727 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Lens Opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0373 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Retina (combined) HOM 8f:7m Not processed Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Calcium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.862 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / HR HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.164 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:8m Fisher Exact Test framework 0.153 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 0.000319 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Hematocrit HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.324 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.719 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000932 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Creatine kinase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.474 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 0.0140 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Dilation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0748 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.246 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Potassium HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.452 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Phosphorus HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.581 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 0.198 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Viability Primary Screen / Outcome HOM 77f:77m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / End-Diastolic Diameter HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.998 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Large Unstained Cell (LUC) count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.383 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Lymphocyte cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.132 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.135 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0408 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Corneal vascularization HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Triglycerides HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.865 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 0.0248 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Platelet count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.738 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Total protein HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.186 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / Respiration Rate HOM 6f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.783 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Position HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.114 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Latency to center entry HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.000230 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Eyelid closure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / LVIDd HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.959 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Aspartate aminotransferase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.820 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Eosinophil cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.734 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.737 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.401 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0110 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.457 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Optic Disc HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.408 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Narrow eye opening HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Sodium HOM 8f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_001_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Shmt1tm1b(KOMP)Wtsi MRC Harwell Organ Weight / Heart weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.682 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.956 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Neutrophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.938 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / HDL-cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.567 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Persistence of hyaloid vascular system HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.422 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.586 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Shape HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0136 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Eye HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Lymphocyte differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.905 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / Stroke Volume HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.763 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Monocyte differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.682 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:8m Fisher Exact Test framework 0.0229 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.246 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Number of ribs right HOM 5f:5m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00822 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Alpha-amylase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.259 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Synechia HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Iron HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.242 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Total cholesterol HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.465 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.301 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Albumin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.443 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0128 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / LVAWd HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.277 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Number of center entries HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0167 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.464 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Eyelid morphology HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / LVPWs HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.970 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Mean cell volume HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.858 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 0.0105 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Cornea HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.314 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Basophil cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.162 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.297 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / Ejection Fraction HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.578 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.647 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Red blood cell count HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.697 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Iris Pigmentation HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.984 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Neutrophil cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.502 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 0.0180 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Number of digits HOM 5f:5m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.524 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Periphery resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0122 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Organ Weight / Spleen weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.398 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Fructosamine HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.806 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Alkaline phosphatase HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.00703 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Monocyte cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.582 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.386 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / End-Systolic Diameter HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.605 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Number of ribs left HOM 5f:5m 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.287 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Fusion between cornea and lens HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 0.00351 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Mean corpuscular hemoglobin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.776 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / LVIDs HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.572 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / Cardiac Output HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withWeight 0.736 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0962 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.118 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Total bilirubin HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.260 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.183 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Basophil differential count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.166 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Center resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.945 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Glucose HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.235 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Retinal Blood Vessels Structure HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Echo / Fractional Shortening HOM 8f:0m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.634 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / Red blood cell distribution width HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.635 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Shmt1tm1b(KOMP)Wtsi MRC Harwell Clinical Chemistry / Chloride HOM 8f:7m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_003_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Shmt1tm1b(KOMP)Wtsi MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.346 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.749 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell X-ray / Tibia length HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.939 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Pupil Light Response HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00820 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Eye Morphology / Corneal opacity HOM 8f:7m Fisher Exact Test framework 1.00 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Hematology / White blood cell count HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.189 Success
Shmt1tm1b(KOMP)Wtsi MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No  (2/2)  Wholemount images
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/4) N/A
Ear 2  (1/485)  (1/4) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (4/4) N/A
Foot 2  (1/485)  (3/4) N/A
Forebrain 2  (1/485)  (4/4) N/A
Forelimb 2  (1/485)  (3/4) N/A
Hand 2  (1/485)  (4/4) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (4/4) N/A
Hindlimb 2  (1/485)  (3/4) N/A
Liver 2  (1/485)  (2/4) N/A
Lung 2  (1/485)  (2/4) N/A
Mandibular process 2  (1/485)  (1/4) N/A
Maxillary process 2  (1/485)  (1/4) N/A
Midbrain 2  (1/485)  (4/4) N/A
Oral cavity 2  (1/485)  (2/4) N/A
Skin 2  (1/485)  (2/4) N/A
Tail 2  (1/485)  (3/4) N/A
Tail somite 2  (1/485)  (3/4) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Lateral Orientation
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Dorso Ventral
10 Images
Adult LacZ: LacZ Images Wholemount
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Shmt1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Shmt1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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