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Gene: Scn3a MGI:98249

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
sodium channel, voltage-gated, type III, alpha
Synonyms:
LOC381367,  Nav1.3

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Scn3a mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Scn3a by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Non-Specific Early-Onset Epileptic Encephalopathy
Unsteady gait, Ataxia, Attention deficit hyperactivity disorder, Difficulty walking ORPHA:442835
Developmental And Epileptic Encephalopathy 62
Inability to walk OMIM:617938
Epilepsy, Familial Focal, With Variable Foci 4
OMIM:617935

The table below shows human diseases predicted to be associated to Scn3a by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Maturity-Onset Diabetes Of The Young, Type 13
Maturity-onset diabetes of the young, Maternal diabetes OMIM:616329
Maturity-Onset Diabetes Of The Young, Type 2
Maturity-onset diabetes of the young OMIM:125851
Maturity-Onset Diabetes Of The Young, Type 9
Maturity-onset diabetes of the young OMIM:612225
Maturity-Onset Diabetes Of The Young, Type 4
Maturity-onset diabetes of the young, Type II diabetes mellitus OMIM:606392
Maturity-Onset Diabetes Of The Young, Type 6
Maturity-onset diabetes of the young OMIM:606394
Maturity-Onset Diabetes Of The Young, Type 7
Maturity-onset diabetes of the young, Type II diabetes mellitus OMIM:610508
Type 1 Diabetes Mellitus 20
Type I diabetes mellitus OMIM:612520
Type 1 Diabetes Mellitus 2
Diabetes mellitus, Type I diabetes mellitus OMIM:125852
Maturity-Onset Diabetes Of The Young, Type 14
Maturity-onset diabetes of the young, Diabetes mellitus OMIM:616511
Type 1 Diabetes Mellitus 15
Diabetes mellitus, Type I diabetes mellitus OMIM:601666
Type 1 Diabetes Mellitus 6
Diabetes mellitus OMIM:601941
Type 1 Diabetes Mellitus 10
Diabetes mellitus OMIM:601942
Diabetes Mellitus, Transient Neonatal, 2
Type II diabetes mellitus, Transient neonatal diabetes mellitus OMIM:610374
Maturity-Onset Diabetes Of The Young, Type 1
Maturity-onset diabetes of the young OMIM:125850
Pancreas, Dorsal, Agenesis Of
Diabetes mellitus OMIM:167755
Maturity-Onset Diabetes Of The Young, Type 3
Hyperglycemia, Maturity-onset diabetes of the young, Type II diabetes mellitus OMIM:600496
Hyperinsulinemic Hypoglycemia, Familial, 3
Hyperinsulinemic hypoglycemia, Hypoglycemic seizures, Diabetes mellitus OMIM:602485
Type 2 Diabetes Mellitus
Type II diabetes mellitus, Insulin resistance OMIM:125853
Maturity-Onset Diabetes Of The Young, Type 10
Hyperglycemia, Diabetic ketoacidosis, Maturity-onset diabetes of the young, Diabetes mellitus OMIM:613370
Wolfram-Like Syndrome, Autosomal Dominant
Glucose intolerance, Impaired glucose tolerance, Diabetes mellitus OMIM:614296
Maturity-Onset Diabetes Of The Young, Type 11
Maturity-onset diabetes of the young, Diabetes mellitus OMIM:613375
Insulinomatosis And Diabetes Mellitus
Hyperinsulinemic hypoglycemia, Glucose intolerance, Impaired glucose tolerance, Diabetes mellitus OMIM:147630
Developmental And Epileptic Encephalopathy 92
Dystonia, Ataxia, Inability to walk, Difficulty walking, Lethargy OMIM:617829
Methylmalonic Acidemia With Homocystinuria, Type Cbld
Gait disturbance, Lethargy ORPHA:79283
Glut1 Deficiency Syndrome 1
Paroxysmal dystonia, Paroxysmal lethargy, Ataxia, Confusion, Lethargy OMIM:606777
Mitochondrial Complex V (Atp Synthase) Deficiency, Nuclear Type 6
Ataxia, Bradykinesia, Lethargy OMIM:618683
Hypothyroidism, Congenital, Nongoitrous, 7
Lethargy OMIM:618573
Mitochondrial Complex I Deficiency, Nuclear Type 3
Dystonia, Ataxia, Lethargy OMIM:618224
Encephalopathy, Acute, Infection-Induced (Herpes-Specific), Susceptibility To, 8
Confusion, Lethargy OMIM:617900
Thiamine Metabolism Dysfunction Syndrome 4 (Bilateral Striatal Degeneration And Progressive Polyneuropathy Type)
Difficulty walking, Lethargy OMIM:613710
Homocystinuria Without Methylmalonic Aciduria
Ataxia, Lethargy ORPHA:622
Immunodeficiency 83, Susceptibility To Viral Infections
Confusion, Lethargy OMIM:613002
Methylmalonic Acidemia With Homocystinuria
Gait disturbance, Lethargy ORPHA:26
Hyperlysinuria With Hyperammonemia
Coma, Lethargy OMIM:238750
N-Acetylglutamate Synthase Deficiency
Coma, Confusion, Lethargy OMIM:237310
Glycine Encephalopathy
Hyperactivity, Lethargy OMIM:605899
Autosomal Recessive Dopa-Responsive Dystonia
Bradykinesia, Focal dystonia, Ataxia, Limb dystonia, Generalized dystonia, Oculogyric crisis, Gai... ORPHA:101150
Developmental And Epileptic Encephalopathy 41
Inability to walk, Lethargy OMIM:617105
Dihydropyrimidine Dehydrogenase Deficiency
Hyperactivity, Lethargy OMIM:274270
Gaba-Transaminase Deficiency
Lethargy OMIM:613163
Classic Glucose Transporter Type 1 Deficiency Syndrome
Confusion, Dystonia, Ataxia, Lethargy ORPHA:71277
Lethal Infantile Mitochondrial Myopathy
Lethargy ORPHA:254857
Mitochondrial Complex I Deficiency, Nuclear Type 4
Ataxia, Lethargy OMIM:618225
Dihydrolipoamide Dehydrogenase Deficiency
Dystonia, Ataxia, Lethargy OMIM:246900
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies
Hyperglycemia, Glucose intolerance OMIM:307500
Febrile Infection-Related Epilepsy Syndrome
Lethargy ORPHA:163703
Early Myoclonic Encephalopathy
Lethargy ORPHA:1935
Mitochondrial Complex I Deficiency, Nuclear Type 6
Lethargy OMIM:618228
Short Chain Acyl-Coa Dehydrogenase Deficiency
Dystonia, Lethargy ORPHA:26792
Vitamin B12-Responsive Methylmalonic Acidemia
Coma, Lethargy ORPHA:28
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Coma, Drowsiness, Lethargy ORPHA:276608
Pyruvate Dehydrogenase E1-Alpha Deficiency
Dystonia, Episodic ataxia, Lethargy OMIM:312170
Multiple Mitochondrial Dysfunctions Syndrome 1
Lethargy OMIM:605711
Severe Canavan Disease
Inability to walk, Lethargy ORPHA:314911
Acyl-Coa Dehydrogenase, Short-Chain, Deficiency Of
Lethargy OMIM:201470
Cirrhosis, Familial
Lethargy OMIM:215600
Dopa-Responsive Dystonia
Dystonia, Gait disturbance, Arm dystonia, Inability to walk, Generalized dystonia, Oculogyric cri... ORPHA:255
Citrullinemia Type I
Torticollis, Ataxia, Coma, Loss of consciousness, Lethargy ORPHA:247525
Hyperinsulinism Due To Ucp2 Deficiency
Hypoglycemic coma, Loss of consciousness, Drowsiness, Lethargy ORPHA:276556
Central Neurocytoma
Ataxia, Coma, Lethargy ORPHA:73256
Encephalopathy, Recurrent, Of Childhood
Athetosis, Truncal ataxia, Lethargy OMIM:130950
Mitochondrial Complex I Deficiency, Nuclear Type 5
Dystonia, Ataxia, Lethargy OMIM:618226
Hyperammonemia Due To N-Acetylglutamate Synthase Deficiency
Drowsiness, Ataxia, Coma, Loss of consciousness, Delirium, Confusion, Lethargy ORPHA:927
Hereditary Central Diabetes Insipidus
Lethargy ORPHA:30925
Cyclic Vomiting Syndrome
Ataxia, Attention deficit hyperactivity disorder, Lethargy OMIM:500007
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Hypoglycemic coma, Loss of consciousness, Drowsiness, Lethargy ORPHA:276575
Glycerol Kinase Deficiency
Coma, Loss of consciousness, Lethargy OMIM:307030
Combined Oxidative Phosphorylation Deficiency 2
Lethargy OMIM:610498
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency
Hypoglycemic coma, Loss of consciousness, Drowsiness, Lethargy ORPHA:276580
Homocystinuria-Megaloblastic Anemia, Cble Complementation Type
Gait disturbance, Lethargy OMIM:236270
Hyperinsulinism Due To Hnf1A Deficiency
Hypoglycemic coma, Loss of consciousness, Drowsiness, Lethargy ORPHA:324575
Multiple Mitochondrial Dysfunctions Syndrome 2 With Hyperglycinemia
Ataxia, Lethargy OMIM:614299
Leukoencephalopathy With Vanishing White Matter
Unsteady gait, Gait disturbance, Lethargy OMIM:603896
Carnitine Deficiency, Systemic Primary
Coma, Confusion, Excessive daytime somnolence, Lethargy OMIM:212140
Thyroid Dyshormonogenesis 1
Lethargy OMIM:274400
2-Methylbutyryl-Coa Dehydrogenase Deficiency
Lethargy OMIM:610006
Mitochondrial Complex V (Atp Synthase) Deficiency, Nuclear Type 5
Gait imbalance, Lethargy OMIM:618120
Vitamin B12-Unresponsive Methylmalonic Acidemia Type Mut0
Dystonia, Coma, Lethargy ORPHA:289916
Crigler-Najjar Syndrome
Lethargy ORPHA:205
Ornithine Transcarbamylase Deficiency, Hyperammonemia Due To
Lethargy, Ataxia, Coma, Episodic ataxia OMIM:311250
Carnitine Palmitoyl Transferase 1A Deficiency
Coma, Loss of consciousness, Lethargy ORPHA:156
Central Diabetes Insipidus
Excessive daytime somnolence, Lethargy ORPHA:178029
Susac Syndrome
Gait ataxia, Confusion, Lethargy ORPHA:838
Benign Samaritan Congenital Myopathy
Lethargy ORPHA:324581
Isovaleric Acidemia
Coma, Lethargy OMIM:243500
Mitochondrial Complex Iii Deficiency, Nuclear Type 8
Gait disturbance, Ataxia, Lethargy OMIM:615838
Estrogen Resistance
Glucose intolerance, Impaired glucose tolerance, Hyperinsulinemia OMIM:615363
Hemochromatosis, Type 2A
Lethargy OMIM:602390
Multiple Carboxylase Deficiency
Ataxia, Coma, Lethargy ORPHA:148
Dihydropyrimidinase Deficiency
Excessive daytime somnolence, Lethargy OMIM:222748
Hemochromatosis Type 2
Lethargy ORPHA:79230
Vitamin B12-Unresponsive Methylmalonic Acidemia Type Mut-
Dystonia, Coma, Lethargy ORPHA:79312
Mitochondrial Complex I Deficiency, Nuclear Type 9
Lethargy OMIM:618232
Hyperphenylalaninemia, Bh4-Deficient, B
Dystonia, Lethargy OMIM:233910
Carbamoyl Phosphate Synthetase I Deficiency, Hyperammonemia Due To
Ataxia, Coma, Lethargy OMIM:237300
Classic Galactosemia
Dystonia, Gait disturbance, Gait imbalance, Ataxia, Attention deficit hyperactivity disorder, Let... ORPHA:79239
Myxedema
Lethargy OMIM:255900
Vitamin B12-Unresponsive Methylmalonic Acidemia
Ataxia, Coma, Lethargy ORPHA:27
Galactosemia
Dystonia, Gait disturbance, Gait imbalance, Ataxia, Lethargy ORPHA:352
Combined Oxidative Phosphorylation Deficiency 52
Lethargy OMIM:619386
Idiopathic Congenital Hypothyroidism
Lethargy ORPHA:95717
Typhoid
Ataxia, Coma, Lethargy ORPHA:99745
Pyruvate Dehydrogenase Deficiency
Dystonia, Gait disturbance, Ataxia, Lethargy ORPHA:765
Maple Syrup Urine Disease
Ataxia, Coma, Lethargy OMIM:248600
Medium Chain Acyl-Coa Dehydrogenase Deficiency
Ataxia, Loss of consciousness, Coma, Lethargy ORPHA:42
Thiamine-Responsive Megaloblastic Anemia Syndrome
Lethargy ORPHA:49827
Acrodermatitis Enteropathica, Zinc-Deficiency Type
Ataxia, Lethargy OMIM:201100
Insulinoma
Lethargy, Fluctuations in consciousness, Coma, Reduced consciousness/confusion ORPHA:97279
Thiamine Metabolism Dysfunction Syndrome 2 (Biotin- Or Thiamine-Responsive Type)
Dystonia, Coma, Inability to walk, Craniofacial dystonia, Gait ataxia, Confusion, Lethargy OMIM:607483
Holocarboxylase Synthetase Deficiency
Ataxia, Coma, Lethargy ORPHA:79242
Idiopathic Intracranial Hypertension
Lethargy ORPHA:238624
Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome
Coma, Confusion, Lethargy OMIM:238970
Mitochondrial Complex Iv Deficiency, Nuclear Type 20
Lethargy OMIM:619064
Pyruvate Dehydrogenase E3 Deficiency
Ataxia, Lethargy ORPHA:2394
Carnitine Palmitoyltransferase I Deficiency
Coma, Lethargy OMIM:255120
Glutaric Acidemia Type 3
Lethargy ORPHA:35706
Citrullinemia Type Ii
Drowsiness, Hyperactivity, Coma, Fluctuations in consciousness, Delirium, Confusion, Lethargy ORPHA:247585
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of
Coma, Lethargy OMIM:201450
Evans Syndrome
Lethargy ORPHA:1959
3-Methylcrotonyl-Coa Carboxylase 1 Deficiency
Coma, Lethargy OMIM:210200
Hypercalcemia, Infantile, 1
Lethargy OMIM:143880
Infantile Liver Failure Syndrome 2
Lethargy OMIM:616483
Methylcobalamin Deficiency Type Cble
Drowsiness, Loss of consciousness, Excessive daytime somnolence, Lethargy ORPHA:2169
Carnitine Palmitoyltransferase Ii Deficiency, Infantile
Lethargy OMIM:600649
Methylmalonic Aciduria Due To Methylmalonyl-Coa Mutase Deficiency
Coma, Lethargy OMIM:251000
Meningococcal Meningitis
Lethargy, Drowsiness, Reduced consciousness/confusion ORPHA:33475
Ogden Syndrome
Torticollis, Shuffling gait, Excessive daytime somnolence, Lethargy ORPHA:276432
Encephalopathy, Progressive, Early-Onset, With Brain Edema And/Or Leukoencephalopathy, 2
Dystonia, Ataxia, Lethargy OMIM:618321
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Lethargy ORPHA:2089
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia
Lethargy OMIM:611590
Hyperinsulinism Due To Hnf4A Deficiency
Coma, Drowsiness, Lethargy ORPHA:263455
Fructose-1,6-Bisphosphatase Deficiency
Coma, Lethargy OMIM:229700
Methylmalonic Aciduria And Homocystinuria, Cbld Type
Dystonia, Spastic ataxia, Lethargy OMIM:277410
Methylmalonic Aciduria And Homocystinuria, Cblj Type
Lethargy OMIM:614857
Propionic Acidemia
Dystonia, Coma, Lethargy OMIM:606054
Scrub Typhus
Lethargy, Reduced consciousness/confusion ORPHA:83317
Carbonic Anhydrase Va Deficiency, Hyperammonemia Due To
Lethargy OMIM:615751
Spinocerebellar Ataxia, X-Linked 3
Dysmetria, Lethargy OMIM:301790
Familial Thyroid Dyshormonogenesis
Lethargy ORPHA:95716
Holocarboxylase Synthetase Deficiency
Coma, Lethargy OMIM:253270
Aromatic L-Amino Acid Decarboxylase Deficiency
Athetosis, Torticollis, Limb dystonia, Oculogyric crisis, Blepharospasm, Lethargy OMIM:608643
Pseudo-Torch Syndrome 2
Lethargy OMIM:617397
Visceral Steatosis, Congenital
Coma, Neonatal death, Lethargy OMIM:228100
Combined Oxidative Phosphorylation Deficiency 11
Lethargy OMIM:614922
Dengue Fever
Lethargy ORPHA:99828
Carnitine-Acylcarnitine Translocase Deficiency
Coma, Lethargy OMIM:212138
Staphylococcal Necrotizing Pneumonia
Confusion, Lethargy ORPHA:36238
Methylmalonic Aciduria, Cblb Type
Coma, Lethargy OMIM:251110
Medulloblastoma
Cerebellar ataxia associated with quadrupedal gait, Dysmetria, Progressive cerebellar ataxia, Ata... ORPHA:616
Transcobalamin Ii Deficiency
Ataxia, Lethargy OMIM:275350
Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of
Lethargy OMIM:201475
Mitochondrial Trifunctional Protein Deficiency
Coma, Tip-toe gait, Lethargy ORPHA:746
3-Methylcrotonyl-Coa Carboxylase 2 Deficiency
Coma, Lethargy OMIM:210210
Citrullinemia, Classic
Ataxia, Coma, Lethargy OMIM:215700
Methylmalonic Aciduria, Cbla Type
Coma, Lethargy OMIM:251100
Carnitine-Acylcarnitine Translocase Deficiency
Coma, Lethargy ORPHA:159
Encephalitis Lethargica
Coma, Lethargy ORPHA:83600
Resistance To Thyrotropin-Releasing Hormone Syndrome
Lethargy ORPHA:99832
Hyperinsulinism Due To Short Chain 3-Hydroxylacyl-Coa Dehydrogenase Deficiency
Confusion, Lethargy ORPHA:71212
Kufor-Rakeb Syndrome
Confusion, Gait disturbance, Lingual dystonia, Bradykinesia, Oculogyric crisis, Blepharospasm, Di... ORPHA:306674
Symptomatic Form Of Hemochromatosis Type 1
Lethargy ORPHA:465508
Mitochondrial Trifunctional Protein Deficiency
Lethargy OMIM:609015
Necrotizing Enterocolitis
Lethargy ORPHA:391673
Methylmalonic Aciduria And Homocystinuria, Cblc Type
Delirium, Confusion, Lethargy OMIM:277400
3-Hydroxy-3-Methylglutaric Aciduria
Ataxia, Hypoglycemic coma, Coma, Lethargy ORPHA:20
Homocystinuria Due To Methylene Tetrahydrofolate Reductase Deficiency
Gait disturbance, Ataxia, Lethargy ORPHA:395
Carnitine Palmitoyltransferase Ii Deficiency, Lethal Neonatal
Lethargy OMIM:608836
Trichinellosis
Lethargy, Confusion, Excessive daytime somnolence, Reduced consciousness/confusion ORPHA:863
Methylmalonic Aciduria And Homocystinuria, Cblf Type
Lethargy OMIM:277380
Biotinidase Deficiency
Ataxia, Lethargy OMIM:253260
Hyperornithinemia-Hyperammonemia-Homocitrullinuria Syndrome
Spastic gait, Progressive cerebellar ataxia, Coma, Confusion, Lethargy ORPHA:415
Genetic Transient Congenital Hypothyroidism
Lethargy ORPHA:226316
Argininosuccinic Aciduria
Ataxia, Coma, Lethargy OMIM:207900
Familial Hypoaldosteronism
Lethargy ORPHA:427
Cholera
Loss of consciousness, Lethargy ORPHA:173
Ebola Hemorrhagic Fever
Lethargy ORPHA:319218
Methylmalonic Acidemia With Homocystinuria Type Cblf
Lethargy ORPHA:79284
Autosomal Dominant Progressive External Ophthalmoplegia
Gait disturbance, Bradykinesia, Ataxia, Gait ataxia, Lethargy ORPHA:254892
Amoebiasis Due To Free-Living Amoebae
Ataxia, Coma, Loss of consciousness, Confusion, Lethargy ORPHA:68
Hereditary Fructose Intolerance
Coma, Lethargy ORPHA:469
Hypothyroidism Due To Tsh Receptor Mutations
Lethargy ORPHA:90673
Very Long Chain Acyl-Coa Dehydrogenase Deficiency
Lethargy ORPHA:26793
Sim1-Related Prader-Willi-Like Syndrome
Lethargy ORPHA:398079
Isolated Thyroid-Stimulating Hormone Deficiency
Attention deficit hyperactivity disorder, Lethargy ORPHA:90674
Glycine Encephalopathy
Lethargy ORPHA:407
Biotinidase Deficiency
Ataxia, Lethargy ORPHA:79241
Isolated Complex I Deficiency
Ataxia, Lethargy ORPHA:2609
Magel2-Related Prader-Willi-Like Syndrome
Lethargy ORPHA:398069
Posterior Urethral Valve
Lethargy ORPHA:93110
Pineoblastoma
Lethargy, Reduced consciousness/confusion ORPHA:251909
Methylmalonic Acidemia With Homocystinuria, Type Cblc
Ataxia, Delirium, Lethargy ORPHA:79282
Late-Onset Isolated Acth Deficiency
Lethargy ORPHA:199299
Histiocytoid Cardiomyopathy
Drowsiness, Loss of consciousness, Lethargy ORPHA:137675
Complete Atrioventricular Septal Defect
Lethargy ORPHA:1329
Mitochondrial Complex I Deficiency, Nuclear Type 1
Ataxia, Coma, Lethargy OMIM:252010
Exercise-Induced Malignant Hyperthermia
Ataxia, Delirium, Confusion, Lethargy ORPHA:466650
Hydranencephaly
Lethargy ORPHA:2177
Marburg Hemorrhagic Fever
Coma, Drowsiness, Confusion, Lethargy ORPHA:99826
Semilobar Holoprosencephaly
Inability to walk, Attention deficit hyperactivity disorder, Limb dystonia, Lethargy ORPHA:220386
Alobar Holoprosencephaly
Inability to walk, Attention deficit hyperactivity disorder, Limb dystonia, Lethargy ORPHA:93925
Midline Interhemispheric Variant Of Holoprosencephaly
Inability to walk, Attention deficit hyperactivity disorder, Limb dystonia, Lethargy ORPHA:93926
Lobar Holoprosencephaly
Inability to walk, Attention deficit hyperactivity disorder, Limb dystonia, Lethargy ORPHA:93924
Fructose Intolerance, Hereditary
Coma, Lethargy OMIM:229600
Multiple Endocrine Neoplasia Type 1
Confusion, Coma, Decreased vigilance, Lethargy ORPHA:652
Hypothyroidism, Congenital, Nongoitrous, 2
Lethargy OMIM:218700
Hypothyroidism Due To Deficient Transcription Factors Involved In Pituitary Development Or Function
Lethargy ORPHA:226307
Lysinuric Protein Intolerance
Coma, Lethargy ORPHA:470
Blackfan-Diamond Anemia
Lethargy ORPHA:124
Eisenmenger Syndrome
Lethargy ORPHA:97214
Paroxysmal Nocturnal Hemoglobinuria
Lethargy ORPHA:447
Non-Specific Early-Onset Epileptic Encephalopathy
Unsteady gait, Ataxia, Attention deficit hyperactivity disorder, Difficulty walking ORPHA:442835
Developmental And Epileptic Encephalopathy 62
Inability to walk OMIM:617938
Epilepsy, Familial Focal, With Variable Foci 4
OMIM:617935

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Scn3a

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Scn3a.

No publications found that use IMPC mice or data for Scn3a.

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MGI Allele Allele Type Produced
Scn3atm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Scn3atm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells

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