Gene: Rrm2

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Phenotype System Allele Zyg Sex Life Stage P Value
decreased spleen weight Rrm2tm1b(KOMP)Wtsi HET Early adult 1.74×10-10
short tibia Rrm2tm1b(KOMP)Wtsi HET Early adult 3.69×10-05
embryonic lethality prior to organogenesis Rrm2tm1b(KOMP)Wtsi HOM   E9.5 0.00
increased bone mineral content Rrm2tm1b(KOMP)Wtsi HET Early adult 1.65×10-05
preweaning lethality, complete penetrance Rrm2tm1b(KOMP)Wtsi HOM   Early adult 0.00
decreased lean body mass Rrm2tm1b(KOMP)Wtsi HET Early adult 4.44×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Trigeminal V nerve 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/382)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/60)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/73)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/71)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/58)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/56)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/57)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/72)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/71)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
Embryo LacZ: LacZ images wholemount
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Forepaw
8 Images
Adult LacZ: LacZ Images Wholemount
2 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Immunophenotyping: Panel A FCS file(s)
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rrm2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Rrm2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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