Rac1 | Rac family small GTPase 1
Physiological systems
21 / 24 physiological systems tested
10 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system
11 No significant impact
3 Not tested
Data collections
Gene metrics:17Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Rac1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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