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Genes Phenotypes

Gene: Pth1r

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Name
parathyroid hormone 1 receptor
MGI ID
MGI:97801
Synonyms
PPR PTH-related peptide receptor PTH1R PTH/PTHrP receptor Pthr1
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (350) All data table (956)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Pth1rtm1a(EUCOMM)Hmgu HET Early adult 6.85×10-08
preweaning lethality, complete penetrance Pth1rtm1a(EUCOMM)Hmgu HOM   Early adult 0.00
decreased circulating potassium level Pth1rtm1a(EUCOMM)Hmgu HET   Early adult 3.64×10-05
decreased bone mineral content Pth1rtm1a(EUCOMM)Hmgu HET Early adult 1.22×10-06

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
20 Images
X-ray: XRay Images Forepaw
16 Images
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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
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X-ray: XRay Images Skull Lateral Orientation
14 Images
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Anti-nuclear antibody assay
6 Images
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DSS Histology
8 Images
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Eye Morphology: Images Slit Lamp
1 Images
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Ear epidermis immunophenotyping
12 Images
Legacy Phenotype Associated Images
Pth1rtm1a(EUCOMM)Hmgu
HET, Male, WTSI
Pth1rtm1a(EUCOMM)Hmgu
HET, Male, WTSI
Pth1rtm1a(EUCOMM)Hmgu
HET, Male, WTSI
Pth1rtm1a(EUCOMM)Hmgu
HET, Male, WTSI
Pth1rtm1a(EUCOMM)Hmgu
HET, Male, WTSI

View all 94 images

Pth1rtm1a(EUCOMM)Hmgu
HOM, Female, WTSI
Pth1rtm1a(EUCOMM)Hmgu
HOM, Male, WTSI
Pth1rtm1a(EUCOMM)Hmgu
abnormal cornea morphology, HET, Female, WTSI

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pth1rtm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Pth1rtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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