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Gene: Bpifa2 MGI:97787

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Gene Summary

Name:
BPI fold containing family A, member 2
Synonyms:
Bpifa2e,  Psp

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
enlarged epididymis Bpifa2em1(IMPC)Mbp HOM Early adult 0.00
decreased locomotor activity Bpifa2em1(IMPC)Mbp HOM Early adult 0.00
abnormal epididymis morphology Bpifa2em1(IMPC)Mbp HOM Early adult 0.00
decreased thigmotaxis Bpifa2em1(IMPC)Mbp HOM Early adult 3.46×10-09
abnormal behavior Bpifa2em1(IMPC)Mbp HOM Early adult 3.67×10-09

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Lateral Orientation

10 Images

View images
X-ray

XRay Images Whole Body Dorso Ventral

10 Images

View images

Human diseases caused by Bpifa2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Bpifa2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Bpifa2.

There are 2 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
The parotid secretory protein BPIFA2 is a salivary surfactant that affects LPS action. Experimental physiology (May 2020) Bpifa2tm1(KOMP)Vlcg 32390232
BPI Fold-Containing Family A Member 2/Parotid Secretory Protein Is an Early Biomarker of AKI. Journal of the American Society of Nephrology : JASN (August 2017) Bpifa2tm1(KOMP)Vlcg 28775000

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Bpifa2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells
Bpifa2em1(IMPC)Mbp Exon Deletion Mice, Tissue

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