Gene: Pomc

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Name
pro-opiomelanocortin-alpha
MGI ID
MGI:97742
Synonyms
POMC Pomc-1 alpha-MSH alpha-melanocyte stimulating hormone adrenal corticotropic hormone ACTH gamma-melanocyte stimulating hormone beta-melanocyte stimulating hormone gamma-MSH beta-MSH alphaMSH BE beta-endorphin
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal spleen morphology Pomcem1(IMPC)Rbrc HET Late adult 0.00
preweaning lethality, incomplete penetrance Pomcem1(IMPC)Rbrc HOM   Early adult 0.00
enlarged spleen Pomcem1(IMPC)Rbrc HET Late adult 0.00
impaired glucose tolerance Pomcem1(IMPC)Rbrc HET Early adult 8.45×10-10
increased liver weight Pomcem1(IMPC)Rbrc HET Late adult 4.69×10-07

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Gross Pathology and Tissue Collection
3 Images
Eye Morphology: Images Ophthalmoscopy
2 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pomctm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pomcem1(IMPC)Rbrc Indel causing a Frameshift Mutation Mice
Pomctm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells