Prkacb | protein kinase, cAMP dependent, catalytic, beta

GeneMGI:97594Synonyms: cAMP-dependent protein kinase C beta, Pkacb

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetPrkacbem1(IMPC)HheterozygoteEarly adult1.16x10-15 
preweaning lethality, incomplete penetrance1 supporting datasetPrkacbem1(IMPC)HhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prkacbem1(IMPC)HExon Deletionmouse
Prkacbtm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell

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