Gene: Pfn1

Log in to follow
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Pfn1tm1a(EUCOMM)Wtsi HOM   Early adult 0.00
fused cornea and lens Pfn1tm1a(EUCOMM)Wtsi HET Early adult 4.87×10-06
increased circulating magnesium level Pfn1tm1a(EUCOMM)Wtsi HET Early adult 7.84×10-05
increased circulating amylase level Pfn1tm1a(EUCOMM)Wtsi HET Early adult 1.47×10-06
decreased circulating serum albumin level Pfn1tm1a(EUCOMM)Wtsi HET   Early adult 2.53×10-06
decreased total body fat amount Pfn1tm1a(EUCOMM)Wtsi HET   Early adult 3.86×10-05
improved glucose tolerance Pfn1tm1a(EUCOMM)Wtsi HET Early adult 9.32×10-05
corneal opacity Pfn1tm1a(EUCOMM)Wtsi HET Early adult 2.82×10-05
abnormal cornea morphology Pfn1tm1a(EUCOMM)Wtsi HET Early adult 5.59×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2) N/A
Aorta 2 No  (1/590) N/A
Blood vessel 2 No  (2/2) N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (3/590)  (2/2) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No  (1/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (1/2) N/A
Heart 2 No  (1/590)  (2/2) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2) N/A
Large intestine 2 No  (10/590)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (1/590)  (2/2) N/A
Lung 2 No  (1/590)  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/590)  (2/2) N/A
Parathyroid gland 2 No  (1/2) N/A
Peripheral nervous system 2 No  (1/590)  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (1/590)  (1/2) N/A
Prostate gland 2 No  (12/590)  (1/2) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/590)  (2/2) N/A
Spinal cord 2 No  (2/590)  (2/2) N/A
Spleen 2 No  (2/590)  (2/2) N/A
Stomach 2 No  (13/590)  (2/2) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (16/590)  (1/2) N/A
Trachea 2 No  (2/590)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Section Images

View all 27 images

View all 14 images

No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
X-ray: XRay Images Skull Lateral Orientation
13 Images
X-ray: XRay Images Forepaw
12 Images
Legacy Phenotype Associated Images

View all 413 images

View all 14 images

View all 12 images

View all 6 images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Pfn1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Pfn1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter