Gene: Pcx

Name
pyruvate carboxylase
MGI ID
MGI:97520
Synonyms
Pc
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased grip strength Pcxtm1b(EUCOMM)Wtsi HET postnatal 3.87×10-09
preweaning lethality, complete penetrance Pcxtm1b(EUCOMM)Wtsi HOM n/a 0.00
decreased red blood cell distribution width Pcxtm1b(EUCOMM)Wtsi HET postnatal 6.78×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (2/4)  Wholemount images
Aorta 4 No N/A
Blood 2 No N/A
Bone 4 No N/A
Bone marrow 2 No N/A
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (2/4)  Wholemount images
Brown adipose tissue 4 No  (4/4)  Wholemount images
Cartilage tissue 4 No N/A
Cecum 2 No  (12/383) N/A
Cerebellum 4 No  (2/4)  Wholemount images
Cerebral cortex 4 No  Wholemount images
Chest bone 2 No  (2/2)  Wholemount images
Colon 2 No  (12/127) N/A
Cranium 2 No N/A
Diaphragm 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 4 No  (7/415)  Wholemount images
Eye 4 No N/A
Gall bladder 4 No  (1/4)  Wholemount images
Harderian gland 2 No N/A
Heart 4 No N/A
Hindlimb 2 No N/A
Hippocampus 4 No  (2/4)  Wholemount images
Hypothalamus 4 No  (2/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584) N/A
Liver 4 No  (2/4)  Wholemount images
Lower urinary tract 4 No  (2/4)  Wholemount images
Lung 4 No  (3/4)  Wholemount images
Lymph node 4 No  (1/4)  Wholemount images
Main olfactory bulb 2 No N/A
Mammary gland 4 No  (1/4)  Wholemount images
Mesenteric lymph node 2 No N/A
Olfactory lobe 4 No  (2/4)  Wholemount images
Oral epithelium 4 No N/A
Ovary 4 No  (1/584)  (1/4)  Wholemount images
Oviduct 4 No  (1/4)  Wholemount images
Pancreas 4 No  (5/584)  (3/4)  Wholemount images
Parathyroid gland 4 No  (2/4)  Wholemount images
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 4 No  (2/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Sciatic nerve 2 No N/A
Skeletal muscle 4 No  (2/4)  Wholemount images
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (2/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Stomach pyloric region 2 No N/A
Striatum 4 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No  (2/4)  Wholemount images
Thyroid gland 4 No  (15/584)  (2/4)  Wholemount images
Tongue 2 No  (5/127) N/A
Trachea 4 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 4 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 4 No N/A
Vesicular gland 2 No N/A
White adipose tissue 4 No  (3/4)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (1/4) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (3/4) N/A
Eye 2  (1/485)  (1/4) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (1/4) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/4) N/A
Heart 2  (1/485)  (1/4) N/A
Hindbrain 2  (6/485)  (1/4) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (1/4) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (1/4) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
38 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Lateral Orientation
20 Images
X-ray: XRay Images Dorso Ventral
20 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Pcxtm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Pcxtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pcxtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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