Genes Phenotypes

Gene: Furin

Name
furin (paired basic amino acid cleaving enzyme)
MGI ID
MGI:97513
Synonyms
Fur 9130404I01Rik Pcsk3 SPC1 PACE
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (243) All data table (249)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
brachydactyly Furintm1b(EUCOMM)Wtsi HET postnatal 8.75×10-08
abnormal vibrissa morphology Furintm1b(EUCOMM)Wtsi HET postnatal 2.84×10-11
preweaning lethality, complete penetrance Furintm1b(EUCOMM)Wtsi HOM n/a 0.00
embryonic lethality prior to tooth bud stage Furintm1b(EUCOMM)Wtsi HOM embryonic day 12.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4)  Wholemount images
Aorta 4 No  (4/4) N/A
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (4/4)  Wholemount images
Brown adipose tissue 4 No  (4/4)  Wholemount images
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (4/4)  Wholemount images
Esophagus 4 No  (7/415)  (4/4)  Wholemount images
Eye 4 No  (4/4)  Wholemount images
Gall bladder 4 No  (4/4)  Wholemount images
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (4/4)  Wholemount images
Hypothalamus 4 No  (4/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No  (4/4)  Wholemount images
Lower urinary tract 4 No  (4/4)  Wholemount images
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No  (4/4)  Wholemount images
Mammary gland 4 No  (2/4)  Wholemount images
Olfactory lobe 4 No  (4/4)  Wholemount images
Oral epithelium 4 No  (3/4)  Wholemount images
Ovary 4 No  (1/584)  (1/4)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584)  (4/4)  Wholemount images
Parathyroid gland 4 No  (4/4)  Wholemount images
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No  (4/4)  Wholemount images
Pituitary gland 4 No  (4/4)  Wholemount images
Prostate gland 4 No  (12/584)  (2/4)  Wholemount images
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584)  (4/4)  Wholemount images
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584)  (1/4) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No  (4/4)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No  (4/4)  Wholemount images
Thyroid gland 4 No  (15/584)  (4/4)  Wholemount images
Trachea 4 No  (4/4)  Wholemount images
Uterus 4 No  (2/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
LacZ Wholemount Images
adipose tissue (2)
Brown adipose tissue expression
MA:0000057
cardiovascular system (2)
Cartilage tissue expression
Bone expression
Vascular System expression
Brown adipose tissue expression
MA:0000104
MA:0001459
MA:0002718
MA:0000057
digestive system (5)
Large Intestine expression
MA:0000333
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
immune system (3)
Lymph Node expression
MA:0000139
integumental system (5)
Mammary gland expression
MA:0000145
musculoskeletal system (2)
Cartilage tissue expression
Bone expression
Vascular System expression
Brown adipose tissue expression
MA:0000104
MA:0001459
MA:0002718
MA:0000057
nervous system (5)
Brain expression
Brainstem expression
Cerebellum expression
Cerebral Cortex expression
Striatum expression
Hypothalamus expression
Olfactory Lobe expression
Hippocampus expression
MA:0000168
MA:0000169
MA:0000198
MA:0000185
MA:0000891
MA:0000173
MA:0002413
MA:0000191
postnatal mouse (30)
Adrenal gland expression
MA:0000116
reproductive system (4)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (3)
Brown adipose tissue expression
MA:0000057
trunk (16)
Adrenal gland expression
MA:0000116
urinary system (3)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (1/1) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (1/1) N/A
Eye 1  (1/485)  (1/1) N/A
Foot 1  (1/485)  (1/1) N/A
Forebrain 1  (1/485)  (1/1) N/A
Forelimb 1  (1/485)  (1/1) N/A
Hand 1  (1/485)  (1/1) N/A
Head 1  (5/485)  (1/1) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485)  (1/1) N/A
Hindlimb 1  (1/485)  (1/1) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485)  (1/1) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485)  (1/1) N/A
Tail somite 1  (1/485)  (1/1) N/A

 Associated Images

Echo: M-Mode Images
64 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Lateral Orientation
11 Images
X-ray: XRay Images Dorso Ventral
12 Images
Adult LacZ: LacZ Images Wholemount
30 Images
Embryo LacZ: LacZ images wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Furintm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Furintm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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