Gene: Furin

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Name
furin (paired basic amino acid cleaving enzyme)
MGI ID
MGI:97513
Synonyms
Fur PACE SPC1 Pcsk3 9130404I01Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Furintm1b(EUCOMM)Wtsi HOM   E12.5 0.00
brachydactyly Furintm1b(EUCOMM)Wtsi HET Early adult 5.63×10-08
abnormal vibrissa morphology Furintm1b(EUCOMM)Wtsi HET Early adult 1.39×10-11
preweaning lethality, complete penetrance Furintm1b(EUCOMM)Wtsi HOM   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
4 No  (4/583)  (4/4)  Wholemount images
4 No  (1/583)  (4/4) N/A
4 No  (4/4)  Wholemount images
4 No  (4/583)  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No  (1/583)  (4/4)  Wholemount images
4 No  (3/583)  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (7/407)  (4/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (3/583)  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (21/583)  (4/4)  Wholemount images
4 No  (10/583)  (4/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No  (1/583)  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (1/583)  (4/4)  Wholemount images
4 No  (2/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (3/4)  Wholemount images
4 No  (1/583)  (1/4)  Wholemount images
4 No  (2/4)  Wholemount images
4 No  (5/583)  (4/4)  Wholemount images
4 No  (1/563)  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No  (1/583)  (4/4)  Wholemount images
4 No  (12/583)  (2/4)  Wholemount images
4 No N/A
4 No  (1/583)  (4/4)  Wholemount images
4 No  (9/583)  (4/4)  Wholemount images
4 No  (3/583)  (4/4)  Wholemount images
4 No  (3/583)  (1/4) N/A
4 No  (13/583)  (4/4)  Wholemount images
4 No  (3/583)  (4/4)  Wholemount images
4 No  (6/583)  (2/4)  Wholemount images
4 No  (1/583)  (4/4)  Wholemount images
4 No  (17/583)  (4/4)  Wholemount images
4 No  (3/583)  (4/4)  Wholemount images
4 No  (2/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
1  (6/505)  (1/1) N/A
1  (1/505) N/A
1  (1/506)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (5/505)  (1/1) N/A
1  (1/505) N/A
1  (6/505)  (1/1) N/A
1  (1/505)  (1/1) N/A
1  (1/503) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505) N/A
1  (1/505)  (1/1) N/A
1  (1/503) N/A
1  (1/505) N/A
1  (1/505)  (1/1) N/A
1  (1/505)  (1/1) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
30 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
Echo: M-Mode Images
64 Images
Embryo LacZ: LacZ images wholemount
4 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Furintm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Furintm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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