Gene: Pcsk2

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Name
proprotein convertase subtilisin/kexin type 2
MGI ID
MGI:97512
Synonyms
prohormone convertase 2 Nec-2 Phpp-2 Nec2 SPC2 PC2 6330411F23Rik
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
limb grasping Pcsk2em1(IMPC)H HOM Early adult 6.31×10-07
abnormal coat/ hair morphology Pcsk2em1(IMPC)H HOM Early adult 4.88×10-05
preweaning lethality, incomplete penetrance Pcsk2em1(IMPC)H HOM   Early adult 0.00
increased circulating iron level Pcsk2em1(IMPC)H HOM   Early adult 0.00
increased mean corpuscular volume Pcsk2em1(IMPC)H HOM   Early adult 2.21×10-06
increased circulating cholesterol level Pcsk2em1(IMPC)H HOM   Early adult 6.98×10-07
decreased circulating glucose level Pcsk2em1(IMPC)H HOM   Early adult 8.33×10-13
abnormal locomotor behavior Pcsk2em1(IMPC)H HOM   Early adult 1.81×10-05
increased circulating creatinine level Pcsk2em1(IMPC)H HOM   Early adult 9.10×10-05

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 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Pcsk2em1(IMPC)H Exon Deletion Mice
Pcsk2em2(IMPC)H Exon Deletion Mice
Pcsk2tm28831(L1L2_gt0) Targeting vectors

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