Gene: Pcsk1

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Name
proprotein convertase subtilisin/kexin type 1
MGI ID
MGI:97511
Synonyms
Nec-1 Nec1 SPC3 PC1 PC3 Phpp-1 prohormone convertase 1/3
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Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
persistence of hyaloid vascular system Pcsk1tm1b(EUCOMM)Wtsi HET Early adult 3.72×10-08
decreased food intake Pcsk1tm1b(EUCOMM)Wtsi HET Early adult 4.10×10-06
abnormal retinal blood vessel morphology Pcsk1tm1b(EUCOMM)Wtsi HET Early adult 2.86×10-05
abnormal retinal vasculature morphology Pcsk1tm1b(EUCOMM)Wtsi HET Early adult 2.96×10-05
hypoactivity Pcsk1tm1b(EUCOMM)Wtsi HET Early adult 7.46×10-05
preweaning lethality, incomplete penetrance Pcsk1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal vitreous body morphology Pcsk1tm1b(EUCOMM)Wtsi HET Early adult 2.81×10-07

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Pcsk1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Pcsk1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pcsk1tm44480(L1L2_st0) Targeting vectors

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