Gene: Pax7

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Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Pax7tm1.1(KOMP)Vlcg HOM   Early adult 0.00
improved glucose tolerance Pax7tm1.1(KOMP)Vlcg HET Early adult 1.50×10-06
preweaning lethality, incomplete penetrance Pax7tm1.1(KOMP)Vlcg HOM   Early adult 0.00
decreased circulating insulin level Pax7tm1.1(KOMP)Vlcg HET Early adult 3.47×10-05
shortened RR interval Pax7tm1.1(KOMP)Vlcg HET Early adult 9.21×10-05

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Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (4/584) N/A
Aorta 4 No  (1/584) N/A
Blood 2 No N/A
Bone marrow 4 No N/A
Brain 4 No  (4/584)  (2/4)  Section images
Brainstem 4 No  (2/584)  (2/4)  Section images
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (1/584) N/A
Cecum 2 No  (11/370) N/A
Cerebellum 4 No  (3/584) N/A
Cerebral cortex 4 No  (2/584) N/A
Chest bone 2 No N/A
Colon 2 No  (11/126) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (1/126) N/A
Epididymis 4 No  (17/133)  (1/4)  Section images
Esophagus 4 No  (7/408)  (3/4)  Section images
Eye 4 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 4 No  (2/584) N/A
Hindlimb 2 No N/A
Hippocampus 4 No  (3/584) N/A
Hypothalamus 4 No  (2/584) N/A
Ileum 2 No  (13/126) N/A
Jejunum 2 No  (5/126) N/A
Kidney 4 No  (21/584)  (2/4)  Section images
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No  (1/584) N/A
Lung 4 No  (2/584) N/A
Lymph node 4 No  (1/584) N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 4 No  (4/4)  Section images
Olfactory lobe 4 No  (2/584) N/A
Ovary 4 No  (1/584)  (1/4)  Section images
Oviduct 4 No N/A
Pancreas 4 No  (5/584) N/A
Parathyroid gland 2 No  (1/562) N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 4 No  (2/584) N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (1/584) N/A
Prostate gland 4 No  (12/584) N/A
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 4 No  (2/4)  Section images
Skin 4 No  (1/584) N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No  (3/584)  (2/4)  Section images
Spleen 4 No  (3/584) N/A
Stomach 4 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 4 No  (3/584) N/A
Sublingual gland 2 No N/A
Submandibular gland 4 No  (2/131)  (1/4)  Section images
Testis 4 No  (6/584)  (2/4)  Section images
Thalamus 2 No N/A
Thymus 4 No  (1/584) N/A
Thyroid gland 4 No  (16/584) N/A
Tongue 2 No  (5/126)  (2/2)  Section images
Trachea 4 No  (3/584)  (1/4)  Section images
Trigeminal V nerve 2 No N/A
Urinary bladder 4 No N/A
Uterus 4 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (14/381)  (1/2)  Section images
Vascular system 4 No N/A
Vesicular gland 4 No N/A
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/63) N/A
Brain 3  (6/507)  (3/9) N/A
Central nervous system ganglion 2  (1/72)  (2/2) N/A
Dorsal root ganglion 1  (1/59) Image Only N/A
Ear 3  (1/507) N/A
Embryo 3  (1/508)  (3/9)  Wholemount images
Eye 3  (1/507) N/A
Footplate 3  (1/507) N/A
Forebrain 3  (1/507) N/A
Forelimb 3  (1/507)  (1/9) N/A
Fronto-nasal process 1  (1/60) Image Only N/A
Gut 2  (1/58) N/A
Handplate 3  (1/507) N/A
Head 3  (5/507)  (1/9) N/A
Heart 3  (1/507) N/A
Hindbrain 3  (6/507)  (3/9) N/A
Hindlimb 3  (1/507)  (1/9) N/A
Liver 3  (1/502) N/A
Lung 3  (1/502) N/A
Mandibular process 3  (1/507)  (1/9) N/A
Maxillary process 3  (1/507)  (1/9) N/A
Midbrain 3  (1/507)  (3/9) N/A
Nose 3  (1/77)  (1/3) N/A
Oral cavity 3  (1/502) N/A
Skeleton 2  (1/77) N/A
Skin 3  (1/507) N/A
Spinal cord 3  (1/71)  (3/3) N/A
Tail 3  (1/507)  (1/9) N/A
Tail somite group 3  (1/507)  (2/9) N/A
Trachea 2  (1/58) N/A
Urinary system 2  (1/58) N/A

 Associated Images

X-ray: XRay Images Forepaw
20 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
20 Images
Embryo LacZ: LacZ images wholemount
36 Images
Adult LacZ: LacZ Images Section
26 Images
X-ray: XRay Images Whole Body Lateral Orientation
20 Images
X-ray: XRay Images Skull Lateral Orientation
20 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
20 Images
Sleep Wake: Wake state (bmp file)
12 Images
Eye Morphology: Images Ophthalmoscopy
1 Images
Combined SHIRPA and Dysmorphology
1 Images
Electroretinography 2: Rod and cone PDF
2 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Pax7tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Pax7tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Pax7tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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