Gene: Pax4

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Pax4tm1b(EUCOMM)Hmgu HET Early adult 1.30×10-08
tremors Pax4tm1b(EUCOMM)Hmgu HET   Early adult 3.20×10-06
increased circulating total protein level Pax4tm1b(EUCOMM)Hmgu HET Early adult 9.13×10-06
preweaning lethality, complete penetrance Pax4tm1b(EUCOMM)Hmgu HOM   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/507)  (1/1) N/A
Ear 1  (1/507) N/A
Embryo 1  (1/508) Image Only N/A
Eye 1  (1/507) N/A
Footplate 1  (1/507) N/A
Forebrain 1  (1/507) N/A
Forelimb 1  (1/507) N/A
Handplate 1  (1/507) N/A
Head 1  (5/507)  (1/1) N/A
Heart 1  (1/507) N/A
Hindbrain 1  (6/507)  (1/1) N/A
Hindlimb 1  (1/507) N/A
Liver 1  (1/502) N/A
Lung 1  (1/502) N/A
Mandibular process 1  (1/507) N/A
Maxillary process 1  (1/507) N/A
Midbrain 1  (1/507) N/A
Oral cavity 1  (1/502) N/A
Pancreas 1  (1/54)  (1/1) N/A
Skin 1  (1/507) N/A
Tail 1  (1/507) N/A
Tail somite group 1  (1/507) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
1 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Immunophenotyping: Panel A FCS file(s)
6 Images

 Disease Models

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MGI Allele Allele Type Produced
Pax4tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Pax4tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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