Gene: Nras

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Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating glucose level Nrastm1b(EUCOMM)Hmgu HET postnatal 1.43×10-05
prenatal lethality Nrastm1b(EUCOMM)Hmgu HOM embryonic day 18.5 0.00
preweaning lethality, complete penetrance Nrastm1b(EUCOMM)Hmgu HOM n/a 0.00
short tibia Nrastm1b(EUCOMM)Hmgu HET postnatal 9.82×10-05

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 3  (6/485)  (5/5) N/A
Ear 3  (1/485)  (1/5) N/A
Embryo 3  (1/485)  (5/5) N/A
Eye 3  (1/485)  (5/5) N/A
Foot 3  (1/485)  (4/5) N/A
Forebrain 3  (1/485)  (4/5) N/A
Forelimb 3  (1/485) N/A
Hand 3  (1/485)  (4/5) N/A
Head 3  (5/485)  (5/5) N/A
Heart 3  (1/485)  (2/5) N/A
Hindbrain 3  (6/485)  (4/5) N/A
Hindlimb 3  (1/485) N/A
Liver 3  (1/485) N/A
Lung 3  (1/485) N/A
Mandibular process 3  (1/485) N/A
Maxillary process 3  (1/485) N/A
Midbrain 3  (1/485)  (5/5) N/A
Oral cavity 3  (1/485)  (1/5) N/A
Skin 3  (1/485)  (1/5) N/A
Tail 3  (1/485)  (4/5) N/A
Tail somite 3  (1/485)  (2/5) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
7 Images
X-ray: XRay Images Lateral Orientation
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Dorso Ventral
9 Images
Echo: M-Mode Images
32 Images
Adult LacZ: LacZ Images Wholemount
17 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nrastm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nrastm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Nrastm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Nrastm373486(L1L2_Bact_P) Targeting vectors

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