banner
Genes Phenotypes

Gene: Notch1

Log in to follow
Name
notch 1
MGI ID
MGI:97363
Synonyms
lin-12 Tan1 Mis6 9930111A19Rik Motch A N1
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (231) All data table (501)
Expression & images (67) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Notch1tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
increased grip strength Notch1tm1b(EUCOMM)Hmgu HET Early adult 9.92×10-05
abnormal vertebrae morphology Notch1tm1b(EUCOMM)Hmgu HET Early adult 3.34×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (1/2)  Wholemount images
Aorta 2 No  (1/590)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (3/590)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590)  (2/2)  Wholemount images
Large intestine 2 No  (10/590)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2)  Wholemount images
Lung 2 No  (1/590)  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/590) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/590)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/590)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/590)  (2/2)  Wholemount images
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590)  (2/2)  Wholemount images
Stomach 2 No  (13/590)  (2/2)  Wholemount images
Striatum 2 No  (3/590)  (2/2)  Wholemount images
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (16/590)  (2/2)  Wholemount images
Trachea 2 No  (2/590)  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (3)
Aorta expression
MA:0000062
digestive system (5)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (2)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
immune system (3)
Lymph Node expression
MA:0000139
integumental system (2)
Mammary gland expression
MA:0000145
musculoskeletal system (1)
Cartilage tissue expression
Vascular System expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
nervous system (5)
Brain expression
Cerebral Cortex expression
Hippocampus expression
Striatum expression
MA:0000191
MA:0000891
MA:0000168
MA:0000185
postnatal mouse (27)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (3)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (1)
Cartilage tissue expression
Vascular System expression
Bone expression
MA:0002718
MA:0000104
MA:0001459
trunk (16)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) Image Only N/A
Ear 1  (1/506) Image Only N/A
Embryo 1  (1/507) Image Only N/A
Eye 1  (1/506) Image Only N/A
Foot 1  (1/506) Image Only N/A
Forebrain 1  (1/506) Image Only N/A
Forelimb 1  (1/506) Image Only N/A
Hand 1  (1/506) Image Only N/A
Head 1  (5/506) Image Only N/A
Heart 1  (1/506) Image Only N/A
Hindbrain 1  (6/506) Image Only N/A
Hindlimb 1  (1/506) Image Only N/A
Liver 1  (1/504) Image Only N/A
Lung 1  (1/504) Image Only N/A
Mandibular process 1  (1/506) Image Only N/A
Maxillary process 1  (1/506) Image Only N/A
Midbrain 1  (1/506) Image Only N/A
Oral cavity 1  (1/504) Image Only N/A
Skin 1  (1/506) Image Only N/A
Tail 1  (1/506) Image Only N/A
Tail somite 1  (1/506) Image Only N/A

 Associated Images

thumbnail
Adult LacZ: LacZ Images Wholemount
27 Images
thumbnail
Echo: M-Mode Images
32 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
thumbnail
Embryo LacZ: LacZ images wholemount
8 Images
thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
thumbnail
X-ray: XRay Images Skull Lateral Orientation
1 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Notch1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Notch1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Notch1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter