Gene: Nfkb1

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Name
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
MGI ID
MGI:97312
Synonyms
NF kappaB1 p50 subunit of NF kappaB p50/p105 p50 nuclear factor kappaB p50 NF-kappaB NF-kappaB p50
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal skin condition Nfkb1tm1a(KOMP)Wtsi HOM Early adult 2.02×10-05
decreased circulating sodium level Nfkb1tm1a(KOMP)Wtsi HOM Early adult 5.87×10-07
increased circulating alkaline phosphatase level Nfkb1tm1a(KOMP)Wtsi HOM   Early adult 1.27×10-05
decreased circulating amylase level Nfkb1tm1a(KOMP)Wtsi HOM Early adult 5.76×10-06
increased circulating free fatty acids level Nfkb1tm1a(KOMP)Wtsi HOM   Early adult 5.85×10-05
increased leukocyte cell number Nfkb1tm1a(KOMP)Wtsi HOM   Early adult 2.24×10-07
increased circulating alanine transaminase level Nfkb1tm1a(KOMP)Wtsi HOM Early adult 1.40×10-05
abnormal coat/hair pigmentation Nfkb1tm1a(KOMP)Wtsi HOM   Early adult 4.28×10-06
decreased lean body mass Nfkb1tm1a(KOMP)Wtsi HOM Early adult 5.40×10-05
abnormal cornea morphology Nfkb1tm1a(KOMP)Wtsi HOM Early adult 2.05×10-08
increased circulating aspartate transaminase level Nfkb1tm1a(KOMP)Wtsi HOM Early adult 3.00×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (2/2) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (1/2) N/A
2 No  (4/583)  (2/2) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583)  (2/2) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (1/2) N/A
2 No  (1/2) N/A
2 No  (2/583)  (2/2) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (1/2) N/A
2 No  (10/583)  (2/2) N/A
2 No N/A
2 No  (1/583)  (1/2) N/A
2 No  (2/583)  (2/2) N/A
2 No  (1/583)  (2/2) N/A
2 No N/A
2 No  (2/2) N/A
2 No  (2/583) N/A
2 No  (1/583)  (1/2) N/A
2 No  (1/2) N/A
2 No  (5/583) N/A
2 No  (1/563)  (1/2) N/A
2 No  (2/583)  (2/2) N/A
2 No  (1/176)  (2/2) N/A
2 No  (1/583)  (1/2) N/A
2 No  (12/583) N/A
2 No  (2/2) N/A
2 No  (1/583)  (2/2) N/A
2 No  (9/583)  (2/2) N/A
2 No  (3/583)  (2/2) N/A
2 No  (3/583)  (2/2) N/A
2 No  (13/583)  (2/2) N/A
2 No  (3/583) N/A
2 No  (6/583)  (1/2) N/A
2 No  (1/583)  (2/2) N/A
2 No  (17/583)  (1/2) N/A
2 No  (3/583)  (2/2) N/A
2 No N/A
2 No N/A
LacZ Section Images

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No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images

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 Disease Models

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 Histopathology

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MGI Allele Allele Type Produced
Nfkb1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nfkb1tm272628(L1L2_Bact_P) Targeting vectors