Gene: Nek1

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Name
NIMA (never in mitosis gene a)-related expressed kinase 1
MGI ID
MGI:97303
Synonyms
kat kidney, anemia and testis D8Ertd790e
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal pelvic girdle bone morphology Nek1em1(IMPC)Bay HOM Early adult 2.94×10-05
decreased body length Nek1em1(IMPC)Bay HOM Early adult 5.82×10-29
decreased total body fat amount Nek1em1(IMPC)Bay HOM Early adult 7.42×10-08
decreased prepulse inhibition Nek1em1(IMPC)Bay HOM   Early adult 2.04×10-05
decreased cardiac output Nek1em1(IMPC)Bay HOM Early adult 1.12×10-08
decreased bone mineral content Nek1em1(IMPC)Bay HOM Early adult 8.48×10-17
abnormal heart left ventricle morphology Nek1em1(IMPC)Bay HOM   Early adult 2.58×10-07
decreased cardiac stroke volume Nek1em1(IMPC)Bay HOM Early adult 5.47×10-07
abnormal bone structure Nek1em1(IMPC)Bay HOM Early adult 6.60×10-31
short tibia Nek1em1(IMPC)Bay HOM   Early adult 0.00
abnormal retinal outer nuclear layer morphology Nek1em1(IMPC)Bay HOM Early adult 0.00
decreased grip strength Nek1em1(IMPC)Bay HOM   Early adult 1.70×10-08
abnormal cranium morphology Nek1em1(IMPC)Bay HOM   Early adult 2.69×10-07
decreased total retina thickness Nek1em1(IMPC)Bay HOM Early adult 1.83×10-39
decreased startle reflex Nek1em1(IMPC)Bay HOM Early adult 1.54×10-14

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 Expression

Expression data not available

 Associated Images

Eye Morphology: VIP of right eye
14 Images
Eye Morphology: VIP of left eye
14 Images
Eye Morphology: VIP of right fundus
14 Images
Eye Morphology: VIP of left fundus
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
8 Images
X-ray: XRay Images Skull Lateral Orientation
8 Images
X-ray: XRay Images Forepaw
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
8 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nek1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Nek1em1(IMPC)Bay Exon Deletion Mice, Tissue