Gene: Msx1

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Name
msh homeobox 1
MGI ID
MGI:97168
Synonyms
Hox7 Hox7.1 muscle-segment homeobox msh Hox-7
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Msx1tm1b(KOMP)Wtsi HOM   Early adult 0.00
decreased thigmotaxis Msx1tm1b(KOMP)Wtsi HET Early adult 8.33×10-05
cyanosis Msx1tm1b(KOMP)Wtsi HOM E18.5 0.00
limb grasping Msx1tm1b(KOMP)Wtsi HET   Early adult 3.97×10-05
abnormal facial morphology Msx1tm1b(KOMP)Wtsi HOM E18.5 0.00
cleft palate Msx1tm1b(KOMP)Wtsi HOM E18.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Brain 2 No  (4/583)  (2/2)  Section images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Epididymis 2 No  (18/132) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Heart 2 No  (2/583)  (2/2)  Section images
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Section images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2)  Section images
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Striatum 2 No  (3/583) N/A
Submandibular gland 2 No  (2/130) N/A
Testis 2 No  (6/583)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/3) N/A
1  (1/60) N/A
2  (1/505)  (1/3) N/A
2  (1/506)  (2/3)  Wholemount images
2  (1/505) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
1  (1/61) Image Only N/A
2  (1/505)  (2/3) N/A
2  (5/505)  (2/3) N/A
2  (1/505) N/A
2  (6/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/503) N/A
2  (1/503) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505)  (1/3) N/A
1  (1/75)  (1/1) N/A
2  (1/503)  (1/3) N/A
2  (1/505)  (2/3) N/A
1  (1/72) N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A

 Associated Images

Combined SHIRPA and Dysmorphology
7 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Original Image
Adult LacZ: LacZ Images Section
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Msx1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Msx1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Msx1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice