Gene: Msx1

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Name
msh homeobox 1
MGI ID
MGI:97168
Synonyms
Hox7.1 Hox7 msh muscle-segment homeobox Hox-7
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased thigmotaxis Msx1tm1b(KOMP)Wtsi HET Early adult 4.35×10-06
preweaning lethality, complete penetrance Msx1tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal facial morphology Msx1tm1b(KOMP)Wtsi HET E18.5 0.00
abnormal facial morphology Msx1tm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal embryo size Msx1tm1b(KOMP)Wtsi HOM E12.5 0.00
limb grasping Msx1tm1b(KOMP)Wtsi HET Early adult 5.71×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Brain 2 No  (3/589)  (2/2)  Section images
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/589) N/A
Cerebral cortex 2 No  (2/589) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (1/589)  (2/2)  Section images
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589)  (2/2)  Section images
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/589) N/A
Ovary 2 No  (1/589)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/589) N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (2/2)  Section images
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589)  (2/2)  Section images
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589) N/A
Striatum 2 No  (3/589) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/589)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589) N/A
Urinary bladder 2 No N/A
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/3) N/A
Dorsal root ganglion 1  (1/61) N/A
Ear 2  (1/506)  (1/3) N/A
Embryo 2  (1/507)  (2/3)  Wholemount images
Eye 2  (1/506) N/A
Foot 2  (1/506)  (2/3) N/A
Forebrain 2  (1/506)  (2/3) N/A
Forelimb 2  (1/506)  (2/3) N/A
Fronto-nasal process 1  (1/62) Image Only N/A
Hand 2  (1/505)  (2/3) N/A
Head 2  (5/506)  (2/3) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506)  (2/3) N/A
Hindlimb 2  (1/505)  (2/3) N/A
Liver 2  (1/506) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/506)  (2/3) N/A
Maxillary process 2  (1/506)  (2/3) N/A
Midbrain 2  (1/506)  (1/3) N/A
Nose 1  (1/74)  (1/1) N/A
Oral cavity 2  (1/506)  (1/3) N/A
Skin 2  (1/506)  (2/3) N/A
Spinal cord 1  (1/73) N/A
Tail 2  (1/506)  (2/3) N/A
Tail somite 2  (1/506) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
12 Images
Adult LacZ: LacZ Images Section
11 Images
Combined SHIRPA and Dysmorphology
7 Images
Sleep Wake: Wake state (bmp file)
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Msx1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Msx1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Msx1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells