Mpl | Mpl proto-oncogene, thrombopoietin receptor
Physiological systems
23 / 24 physiological systems tested
11 Significantly impacted by the knock-out
Behavior/neurological Reproductive system Integument Immune system Digestive/alimentary Skeleton Hematopoietic system Respiratory system Endocrine/exocrine gland Cardiovascular system Growth/size/body region
12 No significant impact
1 Not tested
Data collections
Gene metrics:15Significant phenotypes
8Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Mpl mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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