Gene Summary

Name:
N-methylpurine-DNA glycosylase
Synonyms:
Mid1,  3-methyladenine DNA glycosylase,  alkylpurine-DNA-N-glycosylase,  APNG,  Aag

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Mpgtm1a(EUCOMM)Wtsi HOM   Early adult 4.16×10-05

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lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Skull Lateral Orientation

15 Images

X-ray

XRay Images Whole Body Lateral Orientation

14 Images

X-ray

XRay Images Whole Body Dorso Ventral

15 Images

X-ray

XRay Images Forepaw

14 Images

Anti-nuclear antibody assay

Images

6 Images

X-ray

XRay Images Skull Dorso Ventral Orientation

13 Images

DSS Histology

Images

8 Images

Eye Morphology

Images Slit Lamp

1 Images

Ear epidermis immunophenotyping

Images

12 Images

Legacy Phenotype Associated Images

View all 81 images

Human diseases caused by Mpg mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Mpg by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Cramps, Familial Adolescent
Elevated circulating creatine kinase concentration OMIM:218050
Isolated Asymptomatic Elevation Of Creatine Phosphokinase
Elevated circulating creatine kinase concentration ORPHA:206599
Muscle Cramps, Familial
Elevated circulating creatine kinase concentration OMIM:158400
Plasma Fibronectin Deficiency
Reduced circulating fibronectin level OMIM:614101
Pentosuria
Abnormal circulating carbohydrate concentration, Abnormal circulating enzyme concentration ORPHA:2843
Autoimmune Disease
Autoimmunity, Autoimmune antibody positivity OMIM:109100
Diabetes Mellitus, Ketosis-Prone
Autoimmunity, Diabetes mellitus, Insulin resistance, Beta-cell dysfunction OMIM:612227
Pemphigus Vulgaris, Familial
Autoimmunity, Autoimmune antibody positivity OMIM:169610
Complement Component 4, Partial Deficiency Of
Systemic lupus erythematosus OMIM:120790
Hyperinsulinemic Hypoglycemia, Familial, 7
Hypoglycemic seizures, Hyperinsulinemia, Hyperinsulinemic hypoglycemia, Hypoglycemia, Pancreatic ... OMIM:610021
Hyperinsulinemic Hypoglycemia, Familial, 2
Hyperinsulinemic hypoglycemia, Hypoglycemia, Pancreatic islet-cell hyperplasia, Nesidioblastosis OMIM:601820
Lupus Erythematosus Tumidus
Anti-dsDNA antibody positivity, Anti-La/SS-B antibody positivity, Autoimmune antibody positivity,... ORPHA:90283
Insulin Autoimmune Syndrome
Hyperinsulinemic hypoglycemia, Fasting hypoglycemia, Nonketotic hypoglycemia, Autoimmune antibody... ORPHA:411593
Tn Polyagglutination Syndrome
Autoimmunity OMIM:300622
Vacuolar Myopathy With Sarcoplasmic Reticulum Protein Aggregates
Elevated circulating creatine kinase concentration ORPHA:88635
Hyperinsulinemic Hypoglycemia, Familial, 1
Hypoglycemic seizures, Pancreatic islet-cell hyperplasia, Hyperinsulinemic hypoglycemia OMIM:256450
Lipodystrophy, Familial Partial, Type 1
Hypertriglyceridemia, Hepatomegaly, Loss of gluteal subcutaneous adipose tissue, Increased adipos... OMIM:608600
Systemic Lupus Erythematosus 16
Anti-dsDNA antibody positivity, Antinuclear antibody positivity, Perinuclear antineutrophil antib... OMIM:614420
Maturity-Onset Diabetes Of The Young, Type 3
Maturity-onset diabetes of the young, Hyperglycemia, Type II diabetes mellitus OMIM:600496
Complement Component C1S Deficiency
Hashimoto thyroiditis, Hepatitis, Systemic lupus erythematosus OMIM:613783
Maturity-Onset Diabetes Of The Young, Type 10
Diabetic ketoacidosis, Diabetes mellitus, Maturity-onset diabetes of the young, Hyperglycemia OMIM:613370
Hyperinsulinemic Hypoglycemia, Familial, 6
Hypoglycemic seizures, Hyperinsulinemic hypoglycemia, Abnormality of the pancreatic islet cells OMIM:606762
Hashimoto Thyroiditis
Hashimoto thyroiditis, Autoimmune antibody positivity OMIM:140300
Diabetes Mellitus, Transient Neonatal, 3
Hyperglycemia, Maternal diabetes, Transient neonatal diabetes mellitus, Anti-glutamic acid decarb... OMIM:610582
Maturity-Onset Diabetes Of The Young, Type 13
Maturity-onset diabetes of the young, Maternal diabetes, Hyperglycemia, Anti-glutamic acid decarb... OMIM:616329
C1Q Deficiency 1
Autoimmunity, Systemic lupus erythematosus OMIM:613652
Glycogen Storage Disease 0, Liver
Neonatal hypoglycemia, Postprandial hyperglycemia, Fasting hypoglycemia OMIM:240600
Type 1 Diabetes Mellitus
Autoimmunity, Diabetes mellitus, Hyperglycemia OMIM:222100
Alopecia Areata 1
Autoimmunity OMIM:104000
Hyperproinsulinemia
Hyperinsulinemia, Hyperglycemia OMIM:616214
Lipodystrophy, Familial Partial, Type 3
Hypertriglyceridemia, Cirrhosis, Hyperinsulinemia, Maternal diabetes, Loss of gluteal subcutaneou... OMIM:604367
Autoimmune Hemolytic Anemia-Autoimmune Thrombocytopenia-Primary Immunodeficiency Syndrome
Autoimmune hemolytic anemia, Splenomegaly, Systemic lupus erythematosus, Autoimmunity, Autoimmune... ORPHA:444463
Mahvash Disease
Pancreatic alpha-cell hyperplasia, Increased glucagon level, Type II diabetes mellitus, Recurrent... OMIM:619290
Erythrocyte Lactate Transporter Defect
Elevated circulating creatine kinase concentration OMIM:245340
Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome
Hyperinsulinemia, Fasting hypoglycemia, Hypoketotic hypoglycemia, Hyperhidrosis, Hyperinsulinemic... ORPHA:276608
Transient Neonatal Diabetes Mellitus
Maturity-onset diabetes of the young, Maternal diabetes, Hypoinsulinemia, Hypothyroidism, Hypergl... ORPHA:99886
Mucous Membrane Pemphigoid
Autoimmunity ORPHA:46486
Autosomal Recessive Hyperinsulinism Due To Kir6.2 Deficiency
Neonatal hypoglycemia, Diffuse pancreatic islet hyperplasia, Abnormal response to glucagon stimul... ORPHA:79644
Autosomal Dominant Hyperinsulinism Due To Kir6.2 Deficiency
Hypoglycemic seizures, Hyperinsulinemia, Maternal diabetes, Episodic hyperhidrosis, Hypoketotic h... ORPHA:276580
Autosomal Dominant Hyperinsulinism Due To Sur1 Deficiency
Hypoglycemic seizures, Hyperinsulinemia, Episodic hyperhidrosis, Diffuse pancreatic islet hyperpl... ORPHA:276575
Hjv Or Hamp-Related Hemochromatosis
Diabetes mellitus, Congenital hepatic fibrosis, Abnormality of endocrine pancreas physiology, Hyp... ORPHA:79230
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies
Glucose intolerance, Hyperglycemia, Male hypogonadism, Hypergonadotropic hypogonadism OMIM:307500
Complement Component C1R/C1S Deficiency
Autoimmunity OMIM:216950
Diabetes Mellitus, Transient Neonatal, 1
Hyperglycemia, Transient neonatal diabetes mellitus OMIM:601410
Insulinoma
Hyperinsulinemia, Neoplasm of the adrenal gland, Primary hyperparathyroidism, Pituitary prolactin... ORPHA:97279
Lipodystrophy, Familial Partial, Type 2
Hypertriglyceridemia, Hyperinsulinemia, Hepatomegaly, Loss of truncal subcutaneous adipose tissue... OMIM:151660
Maturity-Onset Diabetes Of The Young, Type 8, With Exocrine Dysfunction
Exocrine pancreatic insufficiency, Maturity-onset diabetes of the young, Hyperglycemia, Elevated ... OMIM:609812
Hyperinsulinism Due To Ucp2 Deficiency
Hypoglycemic seizures, Hepatomegaly, Episodic hyperhidrosis, Diffuse pancreatic islet hyperplasia... ORPHA:276556
Eosinophilopenia
Autoimmunity OMIM:131430
Complement Component 2 Deficiency
Systemic lupus erythematosus OMIM:217000
Immunoglobulin A Deficiency 2
Autoimmunity OMIM:609529
Immunoglobulin A Deficiency 1
Autoimmunity OMIM:137100
Acquired Partial Lipodystrophy
Autoimmunity, Insulin resistance, Hepatic steatosis ORPHA:79087
Mody
Neonatal hypoglycemia, Hepatocellular adenoma, Hypoinsulinemia, Pancreatic hypoplasia, Abnormal c... ORPHA:552
Diabetes Mellitus, Permanent Neonatal, 2
Type I diabetes mellitus, Hyperglycemia, Flexion contracture OMIM:618856
Donohue Syndrome
Hyperinsulinemia, Fasting hypoglycemia, Cholestasis, Precocious puberty, Hyperglycemia, Adipose t... OMIM:246200
Bullous Pemphigoid
Autoimmunity, Diabetes mellitus, Anti-BP230 antibody positivity, Anti-BP180 antibody positivity ORPHA:703
Pineal Hyperplasia, Insulin-Resistant Diabetes Mellitus, And Somatic Abnormalities
Hyperinsulinemia, Fasting hypoglycemia, Hyperglycemia, Diabetic ketoacidosis, Hypoglycemia, Postp... OMIM:262190
Febrile Infection-Related Epilepsy Syndrome
Autoimmunity ORPHA:163703
Cone-Rod Synaptic Disorder Syndrome, Congenital Nonprogressive
Hyperglycemia OMIM:618970
Congenital Hyperinsulinism Due To Hnf4A Deficiency
Neonatal hypoglycemia, Hyperinsulinemia, Hepatomegaly, Hypoketotic hypoglycemia, Fasting hypoglyc... ORPHA:263455
Diabetes Mellitus, Permanent Neonatal, 4
Diabetic ketoacidosis, Type I diabetes mellitus, Hyperglycemia, Elevated hemoglobin A1c OMIM:618858
Insulin-Resistance Syndrome Type B
Biliary cirrhosis, Fasting hyperinsulinemia, Postprandial hyperglycemia, Hyperinsulinemia, Antinu... ORPHA:2298
Combined Immunodeficiency Due To Partial Rag1 Deficiency
Autoimmune hemolytic anemia, Neutropenia in presence of anti-neutropil antibodies, Splenomegaly, ... ORPHA:231154
Alpha-Fetoprotein, Hereditary Persistence Of
Elevated circulating alpha-fetoprotein concentration OMIM:615970
Secondary Non-Traumatic Avascular Necrosis
Rheumatoid arthritis, Autoimmunity, Systemic lupus erythematosus ORPHA:399180
Diabetes Mellitus, Permanent Neonatal, 1
Type I diabetes mellitus, Diabetes mellitus, Hyperglycemia, Elevated hemoglobin A1c OMIM:606176
Alopecia Totalis
Autoimmunity, Type I diabetes mellitus ORPHA:700
Pemphigus Erythematosus
Anti-acetylcholine receptor antibody positivity, Autoimmunity, Antinuclear antibody positivity, S... ORPHA:79480
Linear Iga Dermatosis
Autoimmunity ORPHA:46488
Diabetes And Deafness, Maternally Inherited
Hyperglycemia, Type II diabetes mellitus OMIM:520000
Mandibuloacral Dysplasia With Type B Lipodystrophy
Decreased adipose tissue around neck, Hyperinsulinemia, Generalized lipodystrophy, Loss of trunca... OMIM:608612
Igg4-Related Thyroid Disease
Euthyroid goiter, Sclerosing cholangitis, Sialadenitis, Abnormal pituitary gland morphology, Anti... ORPHA:64744
Syndromic Multisystem Autoimmune Disease Due To Itch Deficiency
Cirrhosis, Anti-smooth muscle antibody positivity, Cholangitis, Neutropenia in presence of anti-n... ORPHA:228426
Pituitary Deficiency Due To Empty Sella Turcica Syndrome
Decreased response to growth hormone stimulation test, Pituitary hypothyroidism, Adrenocorticotro... ORPHA:91354
Mitchell-Riley Syndrome
Annular pancreas, Biliary atresia, Pancreatic hypoplasia, Cholestasis, Hyperglycemia, Absent gall... OMIM:615710
Autoimmune Disease, Multisystem, Infantile-Onset, 1
Autoimmune hemolytic anemia, Neutropenia in presence of anti-neutropil antibodies, Type I diabete... OMIM:615952
Neuropathy, Hereditary Motor And Sensory, Okinawa Type
Hyperlipidemia, Hyperglycemia OMIM:604484
Diabetes Mellitus, Permanent Neonatal, 3
Glycosuria, Type I diabetes mellitus, Hyperglycemia OMIM:618857
Acth-Independent Macronodular Adrenal Hyperplasia 2
Decreased circulating ACTH concentration, Macronodular adrenal hyperplasia, Hyperglycemia, Increa... OMIM:615954
Mandibuloacral Dysplasia With Type A Lipodystrophy
Hepatomegaly, Hyperinsulinemia, Hypercholesterolemia, Loss of subcutaneous adipose tissue in limb... OMIM:248370
Immunodeficiency 63 With Lymphoproliferation And Autoimmunity
Autoimmune hemolytic anemia, Autoimmunity, Hepatomegaly, Splenomegaly OMIM:618495
Sjogren Syndrome
Rheumatoid arthritis, Autoimmunity OMIM:270150
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Glycosuria, Ketotic hypoglycemia, Hyperlipidemia, Postprandial hyperglycemia ORPHA:2089
Isolated Sedoheptulokinase Deficiency
Cholestatic liver disease, Steatorrhea, Anemia, Hypochromic microcytic anemia, Inguinal hernia, C... ORPHA:440713
Subcorneal Pustular Dermatosis
Rheumatoid arthritis, Autoimmunity, Systemic lupus erythematosus ORPHA:48377
Autoimmune Hemolytic Anemia, Warm Type
Autoimmune hemolytic anemia, Jaundice, Splenomegaly, Systemic lupus erythematosus, Autoimmunity ORPHA:90033
Short Syndrome
Lipoatrophy, Inguinal hernia, Reduced subcutaneous adipose tissue, Absence of subcutaneous fat, H... OMIM:269880
Diffuse Alveolar Hemorrhage
Antiphospholipid antibody positivity, Rheumatoid factor positive, Antinuclear antibody positivity... ORPHA:90060
Immunodeficiency 7
Autoimmune hemolytic anemia, Autoimmunity, Hepatomegaly, Splenomegaly OMIM:615387
Hnf1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease
Jaundice, Abnormality of endocrine pancreas physiology, Aplasia/Hypoplasia of the pancreas, Abnor... ORPHA:93111
Mixed-Type Autoimmune Hemolytic Anemia
Autoimmune hemolytic anemia, Autoimmunity, Systemic lupus erythematosus ORPHA:90036
Pancreatic And Cerebellar Agenesis
Anemia, Pancreatic hypoplasia, Pancreatic aplasia, Reduced subcutaneous adipose tissue, Hyperglyc... OMIM:609069
Alopecia Universalis
Autoimmunity, Type I diabetes mellitus ORPHA:701
Greig Cephalopolysyndactyly Syndrome
Inguinal hernia, Omphalocele, Camptodactyly of toe, Hyperglycemia, Umbilical hernia, Joint contra... OMIM:175700
Acquired Aneurysmal Subarachnoid Hemorrhage
Leukocytosis, Hypothyroidism, Hyperglycemia, Hypopituitarism, Hypercholesterolemia ORPHA:90065
Bronchiolitis Obliterans
Autoimmunity ORPHA:1303
Cold Agglutinin Disease
Autoimmunity, Hepatomegaly, Splenomegaly ORPHA:56425
Fanconi-Bickel Syndrome
Hypertriglyceridemia, Hepatomegaly, Fasting hypoglycemia, Increased hepatic glycogen content, Hep... ORPHA:2088
Symptomatic Form Of Hfe-Related Hemochromatosis
Cirrhosis, Hepatomegaly, Hepatocellular carcinoma, Testicular atrophy, Portal hypertension, Hypot... ORPHA:465508
Systemic-Onset Juvenile Idiopathic Arthritis
Autoimmunity, Juvenile rheumatoid arthritis, Hepatomegaly, Splenomegaly ORPHA:85414
Combined Oxidative Phosphorylation Deficiency 54
Hyperglycemia, Hypergonadotropic hypogonadism OMIM:619737
Acquired Generalized Lipodystrophy
Cirrhosis, Hyperinsulinemia, Hepatomegaly, Acute pancreatitis, Insulin resistance, Autoimmunity, ... ORPHA:79086
Gamma-Heavy Chain Disease
Autoimmune hemolytic anemia, Hepatomegaly, Rheumatoid arthritis, Splenomegaly, Autoimmunity, Auto... ORPHA:100026
Isolated Permanent Neonatal Diabetes Mellitus
Lower-limb joint contracture, Pancreatic hypoplasia, Glycosuria, Reduced pancreatic beta cells, H... ORPHA:99885
Pemphigus Vulgaris
Anti-desmoglein-1 antibody positivity, Anti-desmoglein-3 antibody positivity, Autoimmunity ORPHA:704
Autoimmune Polyendocrinopathy Type 3
Aplasia/Hypoplasia of the spleen, Antiphospholipid antibody positivity, Biliary cirrhosis, Anteri... ORPHA:227982
Autoimmune Polyendocrinopathy Type 4
Aplasia/Hypoplasia of the spleen, Antiphospholipid antibody positivity, Biliary cirrhosis, Anteri... ORPHA:227990
Necrotizing Enterocolitis
Abnormal glucose homeostasis, Leukocytosis, Hyperglycemia, Thrombocytopenia, Peritonitis, Neutrop... ORPHA:391673
Abdominal Obesity-Metabolic Syndrome 3
Hypertriglyceridemia, Hypercholesterolemia, Hyperglycemia, Type II diabetes mellitus OMIM:615812
Epiphyseal Dysplasia, Multiple, With Early-Onset Diabetes Mellitus
Reduced pancreatic beta cells, Type I diabetes mellitus, Hepatomegaly, Insulin-resistant diabetes... OMIM:226980
Beta-Ketothiolase Deficiency
Hepatomegaly, Leukocytosis, Hyperglycemia, Hypoglycemia, Thrombocytosis ORPHA:134
Hypokalemic Periodic Paralysis
Adrenocortical adenoma, Postprandial hyperglycemia ORPHA:681
Bardet-Biedl Syndrome 9
Hyperglycemia OMIM:615986
Rabson-Mendenhall Syndrome
Increased circulating androgen concentration, Increased serum testosterone level, Fasting hypogly... ORPHA:769
Alstrom Syndrome
Hypertriglyceridemia, Decreased response to growth hormone stimulation test, Hyperinsulinemia, He... OMIM:203800
Mitochondrial Complex Iii Deficiency, Nuclear Type 6
Hypoglycemia, Hyperglycemia OMIM:615453
Perlman Syndrome
Congenital diaphragmatic hernia, Hypoglycemia, Pancreatic islet-cell hyperplasia OMIM:267000
Tyrosinemia, Type I
Cirrhosis, Hepatomegaly, Anemia, Hepatocellular carcinoma, Splenomegaly, Hypoglycemia, Pancreatic... OMIM:276700
Cole Disease
Hyperglycemia OMIM:615522
Combined Immunodeficiency-Enteropathy Spectrum
Autoimmune hemolytic anemia, Peritoneal abscess, Hypoplasia of the thymus, Hashimoto thyroiditis,... ORPHA:436252
Fanconi-Bickel Syndrome
Intrahepatic cholestasis, Hepatomegaly, Fasting hypoglycemia, Glycosuria, Reduced subcutaneous ad... OMIM:227810
Heart Defects, Congenital, And Other Congenital Anomalies
Congenital diaphragmatic hernia, Patent ductus arteriosus, Biliary atresia, Inguinal hernia, Panc... OMIM:600001
Simpson-Golabi-Behmel Syndrome
Congenital diaphragmatic hernia, Hepatomegaly, Inguinal hernia, Omphalocele, Camptodactyly of fin... ORPHA:373
Dend Syndrome
Hyperglycemia, Elevated hemoglobin A1c ORPHA:79134
Igg4-Related Submandibular Gland Disease
Enlarged lacrimal glands, Abnormal salivary gland morphology, Cholangitis, Abnormal pancreas morp... ORPHA:449432
Atypical Werner Syndrome
Delayed puberty, Neoplasm of the thyroid gland, Lipoatrophy, Hyperinsulinemia, Generalized lipody... ORPHA:79474
Leprechaunism
Hyperinsulinemia, Hepatomegaly, Fasting hypoglycemia, Increased circulating renin level, Central ... ORPHA:508
Alpha-Fetoprotein Deficiency
Decreased circulating alpha-fetoprotein concentration OMIM:615969
Thyrotoxic Periodic Paralysis
Thyrotoxicosis with toxic single thyroid nodule, Thyrotoxicosis with diffuse goiter, Thyrotoxicos... ORPHA:79102
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome
Delayed puberty, Central diabetes insipidus, Decreased response to growth hormone stimulation tes... ORPHA:293987
Greenberg Dysplasia
Pancreatic islet-cell hyperplasia, Hepatosplenomegaly, Hepatic calcification, Hepatomegaly OMIM:215140
Multiple Mitochondrial Dysfunctions Syndrome 7
Thrombocytopenia, Hypoglycemia, Hyperglycemia OMIM:620423
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Cholangitis, Periportal fibrosis, Microvesicular hepatic steatosis, Cholestasis, Hyperglycemia, R... OMIM:124000
Pyruvate Carboxylase Deficiency
Hypoglycemia, Hepatomegaly, Hyperglycemia ORPHA:3008
Scorpion Envenomation
Acute pancreatitis, Glycosuria, Hyperhidrosis, Hyperglycemia ORPHA:466677
Cognitive Impairment-Coarse Facies-Heart Defects-Obesity-Pulmonary Involvement-Short Stature-Skeletal Dysplasia Syndrome
Hypothyroidism, Decreased response to growth hormone stimulation test, Hyperglycemia, Patent duct... ORPHA:444077
Simpson-Golabi-Behmel Syndrome, Type 1
Congenital diaphragmatic hernia, Hepatomegaly, Patent ductus arteriosus, Inguinal hernia, Splenom... OMIM:312870
Mitochondrial Complex Iv Deficiency, Nuclear Type 5
Inguinal hernia, Microvesicular hepatic steatosis, Hyperglycemia, Hypoglycemia, Increased hepatoc... OMIM:220111
Bardet-Biedl Syndrome
Hypertriglyceridemia, Impaired fasting glucose, Abnormality of the endocrine system, Hypoplasia o... ORPHA:110

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Mpg

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Mpg.

There are 5 publications which use IMPC produced mice or data.

Title Journal IMPC Allele PubMed ID
A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation. G3 (Bethesda, Md.) (June 2020) Mpgtm1a(EUCOMM)Wtsi PMC7263671
High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation. Nature immunology (December 2019) Mpgtm1a(EUCOMM)Wtsi PMC7338221
Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis. Nature communications (August 2019) Mpgtm1a(EUCOMM)Wtsi PMC6671969
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS biology (April 2019) Mpgtm1a(EUCOMM)Wtsi PMC6459510
Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation. Scientific data (September 2017)