Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
decreased bone mineral content | Mostm1.1(KOMP)Vlcg | HOM | postnatal | 5.46×10-06 | ||
decreased lean body mass | Mostm1.1(KOMP)Vlcg | HOM | postnatal | 5.74×10-05 | ||
abnormal bone structure | Mostm1.1(KOMP)Vlcg | HOM | postnatal | 1.64×10-06 | ||
decreased body length | Mostm1.1(KOMP)Vlcg | HOM | postnatal | 9.31×10-11 |
Gene: Mos
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Expression
IMPC lacZ Expression Data
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 2 | No | (2/584) | N/A | |
Aorta | 2 | No | N/A | ||
Brain | 2 | No | N/A | ||
Brainstem | 2 | No | N/A | ||
Brown adipose tissue | 2 | No | N/A | ||
Cartilage tissue | 2 | No | N/A | ||
Cerebellum | 2 | No | N/A | ||
Cerebral cortex | 2 | No | N/A | ||
Epididymis | 2 | No | (18/134) | N/A | |
Esophagus | 2 | No | (7/415) | N/A | |
Eye | 2 | No | N/A | ||
Heart | 2 | No | N/A | ||
Hippocampus | 2 | No | N/A | ||
Hypothalamus | 2 | No | N/A | ||
Kidney | 2 | No | (18/584) | (2/2) | N/A |
Large intestine | 2 | No | (10/584) | (2/2) | N/A |
Liver | 2 | No | N/A | ||
Lower urinary tract | 2 | No | N/A | ||
Lung | 2 | No | N/A | ||
Lymph node | 2 | No | N/A | ||
Mammary gland | 2 | No | N/A | ||
Midbrain | 2 | No | N/A | ||
Olfactory lobe | 2 | No | N/A | ||
Ovary | 2 | No | (1/584) | (1/2) | N/A |
Oviduct | 2 | No | N/A | ||
Pancreas | 2 | No | (5/584) | N/A | |
Peripheral nervous system | 2 | No | N/A | ||
Peyer's patch | 2 | No | N/A | ||
Pituitary gland | 2 | No | N/A | ||
Prostate gland | 2 | No | (12/584) | N/A | |
Skeletal muscle | 2 | No | N/A | ||
Skin | 2 | No | N/A | ||
Small intestine | 2 | No | (9/584) | N/A | |
Spinal cord | 2 | No | N/A | ||
Spleen | 2 | No | (2/584) | N/A | |
Stomach | 2 | No | (12/584) | N/A | |
Striatum | 2 | No | N/A | ||
Submandibular gland | 2 | No | (2/132) | N/A | |
Testis | 2 | No | (2/584) | (1/2) | N/A |
Thalamus | 2 | No | N/A | ||
Thymus | 2 | No | N/A | ||
Thyroid gland | 2 | No | (15/584) | N/A | |
Trachea | 2 | No | N/A | ||
Urinary bladder | 2 | No | N/A | ||
Uterus | 2 | No | N/A | ||
Vascular system | 2 | No | N/A | ||
Vesicular gland | 2 | No | N/A | ||
White adipose tissue | 2 | No | N/A |
LacZ Wholemount Images
LacZ Section Images
Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
---|---|---|---|---|
Brain | 2 | (6/485) | N/A | |
Dorsal root ganglion | 2 | (1/47) | N/A | |
Ear | 2 | (1/485) | N/A | |
Embryo | 2 | (1/485) | N/A | |
Eye | 2 | (1/485) | N/A | |
Foot | 2 | (1/485) | N/A | |
Forebrain | 2 | (1/485) | N/A | |
Forelimb | 2 | (1/485) | N/A | |
Fronto-nasal process | 2 | (1/48) | N/A | |
Hand | 2 | (1/485) | N/A | |
Head | 2 | (5/485) | N/A | |
Heart | 2 | (1/485) | N/A | |
Hindbrain | 2 | (6/485) | N/A | |
Hindlimb | 2 | (1/485) | N/A | |
Liver | 2 | (1/485) | N/A | |
Lung | 2 | (1/485) | N/A | |
Mandibular process | 2 | (1/485) | N/A | |
Maxillary process | 2 | (1/485) | N/A | |
Midbrain | 2 | (1/485) | N/A | |
Nose | 2 | (1/51) | N/A | |
Oral cavity | 2 | (1/485) | N/A | |
Skin | 2 | (1/485) | N/A | |
Spinal cord | 2 | (1/50) | N/A | |
Tail | 2 | (1/485) | N/A | |
Tail somite | 2 | (1/485) | N/A |
Associated Images
Disease Models
Order Mouse and ES Cells
MGI Allele | Allele Type | Availability |
---|---|---|
Mostm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
Mostm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | Mice |
Mostm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | Mice, Targeting vectors, ES Cells |
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