Gene: Mme

Name
membrane metallo endopeptidase
MGI ID
MGI:97004
Synonyms
CD10 neprilysin 6030454K05Rik neutral endopeptidase NEP
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (38) Expression & images (0) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

Mouseover the data points for more information. Click and drag to zoom the chart. Click on the legends to disable/enable data.

Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Mmeem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mmeem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / RR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0506 Success
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0238 Success
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Lean/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.391 Success
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mmeem1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Mmeem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 0.307 Success
Mmeem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / PR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.817 Success
Mmeem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.135 Success
Mmeem1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.258 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Fat/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.372 Success
Mmeem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.479 Success
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Mmeem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / QRS HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.735 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Fat mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.194 Success
Mmeem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.934 Success
Mmeem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / HR HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0117 Success
Mmeem1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.187 Success
Mmeem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 0.295 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Bone Area HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.883 Success
Mmeem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Body length HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.441 Success
Mmeem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.376 Success
Mmeem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00370 Success
Mmeem1(IMPC)Mbp UC Davis Viability Primary Screen / Outcome HOM 16f:20m Supplied as data Success
Mmeem1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Mmeem1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.487 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / Lean mass HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.822 Success
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Mmeem1(IMPC)Mbp UC Davis Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Mmeem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / ST HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.343 Success
Mmeem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Mmeem1(IMPC)Mbp UC Davis Body Composition (DEXA lean/fat) / BMC/Body weight HOM 8f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0399 Success

 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Mmetm300418(L1L2_Bact_P) Targeting vectors
Mmeem1(IMPC)Mbp Inter-exdel deletion Mice, Tissue

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter