Name
membrane metallo endopeptidase
MGI ID
MGI:97004
Synonyms
CD10
neprilysin
6030454K05Rik
neutral endopeptidase
NEP
Viability
Homozygous - Viable
Significant phenotypes (0)
All measurements (38)
Expression & images (0)
Disease models (0)
Order (2)
View data by physiological system
Significant
Not Significant
Not tested
No results meet the p-value threshold
Filtered by: all phenotypes
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| Allele | Center | Procedure / Parameter | Zygosity | Mutants | Statistical Method |
P Value | Status | |
|---|---|---|---|---|---|---|---|---|
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Cornea | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Not tested (No variation) - OK | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Retina (combined) | HOM | 8f:8m | Not processed | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Auditory Brain Stem Response / 12kHz-evoked ABR Threshold | HOM | 2f:2m | 1.00 | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Electrocardiogram (ECG) / RR | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.0506 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Lens | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Not tested (No variation) - OK | |
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.0238 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Optic Disc | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Not tested (No variation) - OK | |
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Lean/Body weight | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.391 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Retinal Blood Vessels Structure | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Not tested (No variation) - OK | |
| Mmeem1(IMPC)Mbp | UC Davis | Fertility of Homozygous Knock-out Mice / Gross Findings Female | HOM | f:m | Supplied as data | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Auditory Brain Stem Response / Click-evoked ABR threshold | HOM | 2f:2m | 0.307 | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Electrocardiogram (ECG) / PR | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.817 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Auditory Brain Stem Response / 24kHz-evoked ABR Threshold | HOM | 2f:2m | 1.00 | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.135 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.258 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Fat/Body weight | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.372 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.479 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Retinal Blood Vessels | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Not tested (No variation) - OK | |
| Mmeem1(IMPC)Mbp | UC Davis | Electrocardiogram (ECG) / QRS | HOM | 8f:8m | Mixed Model framework, generalized least squares, equation withoutWeight | 0.735 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Fat mass | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.194 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 | HOM | 8f:8m | Mixed Model framework, generalized least squares, equation withoutWeight | 0.934 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Electrocardiogram (ECG) / HR | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.0117 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.187 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Auditory Brain Stem Response / 30kHz-evoked ABR Threshold | HOM | 2f:2m | 0.295 | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Bone Area | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.883 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Auditory Brain Stem Response / 6kHz-evoked ABR Threshold | HOM | 2f:2m | 1.00 | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Body length | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.441 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.376 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.00370 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Viability Primary Screen / Outcome | HOM | 16f:20m | Supplied as data | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Fertility of Homozygous Knock-out Mice / Gross Findings Male | HOM | f:m | Supplied as data | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.487 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / Lean mass | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.822 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Corneal opacity | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Eye Morphology / Lens Opacity | HOM | 8f:8m | Fisher Exact Test framework | 1.00 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Electrocardiogram (ECG) / ST | HOM | 8f:8m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.343 | Success | |
| Mmeem1(IMPC)Mbp | UC Davis | Auditory Brain Stem Response / 18kHz-evoked ABR Threshold | HOM | 2f:2m | 1.00 | Success | ||
| Mmeem1(IMPC)Mbp | UC Davis | Body Composition (DEXA lean/fat) / BMC/Body weight | HOM | 8f:7m | Mixed Model framework, linear mixed-effects model, equation withoutWeight | 0.0399 | Success |