Golga3 | golgin A3

GeneMGI:96958Synonyms: Mea2, G1-499-14, +3 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Hematopoietic system

16 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

male infertility1 supporting datasetGolga3tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
impaired glucose tolerance1 supporting datasetGolga3tm1b(EUCOMM)HmguhomozygoteEarly adult2.88x10-5 
increased circulating alanine transaminase level1 supporting datasetGolga3tm1b(EUCOMM)HmguhomozygoteEarly adult1.39x10-5 
increased circulating alkaline phosphatase level1 supporting datasetGolga3tm1b(EUCOMM)HmguhomozygoteEarly adult1.42x10-16 
decreased hemoglobin content1 supporting datasetGolga3tm1b(EUCOMM)HmguhomozygoteEarly adult7.62x10-6 
increased circulating aspartate transaminase level1 supporting datasetGolga3tm1b(EUCOMM)HmguhomozygoteEarly adult4.25x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Golga3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Golga3tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Golga3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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