Lrp1 | low density lipoprotein receptor-related protein 1
Physiological systems
20 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Mortality/aging Craniofacial Cardiovascular system
11 No significant impact
4 Not tested
Data collections
Gene metrics:10Significant phenotypes
4Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues
Human diseases caused by Lrp1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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