Genes Phenotypes

Gene: Tlr4

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Name
toll-like receptor 4
MGI ID
MGI:96824
Synonyms
Rasl2-8 Lps lipopolysaccharide response
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (86) All data table (251)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged cecum Tlr4tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased heart weight Tlr4tm1.1(KOMP)Vlcg HOM Early adult 1.80×10-06
abnormal cecum morphology Tlr4tm1.1(KOMP)Vlcg HOM Early adult 0.00
enlarged uterus Tlr4tm1.1(KOMP)Vlcg HOM Early adult 0.00
small superior vagus ganglion Tlr4tm1.1(KOMP)Vlcg HOM Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (1/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
postnatal mouse (3)
Epididymis expression
MA:0000397
reproductive system (2)
Epididymis expression
MA:0000397
trunk (3)
Epididymis expression
MA:0000397
urinary system (1)
Kidney expression
MA:0000368
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
6 Images
Adult LacZ: LacZ Images Section
3 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Tlr4tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Tlr4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Tlr4tm380704(L1L2_Bact_P) Targeting vectors

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