Gene: Kcnb1

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Name
potassium voltage gated channel, Shab-related subfamily, member 1
MGI ID
MGI:96666
Synonyms
Kv2.1 Kcr1-1 Shab
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal gait Kcnb1tm1b(EUCOMM)Hmgu HOM postnatal 1.31×10-05
abnormal locomotor behavior Kcnb1tm1b(EUCOMM)Hmgu HOM postnatal 2.44×10-06
hyperactivity Kcnb1tm1b(EUCOMM)Hmgu HOM postnatal 2.72×10-27
abnormal behavior Kcnb1tm1b(EUCOMM)Hmgu HOM postnatal 3.24×10-07
increased mean corpuscular volume Kcnb1tm1b(EUCOMM)Hmgu HOM postnatal 2.46×10-06

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No  (2/2)  Wholemount images
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No  (2/2)  Wholemount images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485)  (2/2) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485)  (2/2) N/A
Eye 1  (1/485)  (2/2) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485)  (2/2) N/A
Forelimb 1  (1/485) N/A
Hand 1  (1/485) N/A
Head 1  (5/485)  (2/2) N/A
Heart 1  (1/485) Image Only N/A
Hindbrain 1  (6/485)  (2/2) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485)  (2/2) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

Echo: M-Mode Images
26 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Adult LacZ: LacZ Images Wholemount
20 Images
X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Kcnb1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Kcnb1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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