Gene: Itpr1

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Name
inositol 1,4,5-trisphosphate receptor 1
MGI ID
MGI:96623
Synonyms
Ip3r InsP3R type I Itpr-1 opt Pcp1 P400 Pcp-1 wblo IP3R1
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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating bilirubin level Itpr1tm1.1(NCOM)Mfgc HET postnatal 3.36×10-05
small epididymis Itpr1tm1.1(NCOM)Mfgc HET postnatal 0.00
abnormal embryo size Itpr1tm1.1(NCOM)Mfgc HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Itpr1tm1.1(NCOM)Mfgc HOM embryonic day 12.5 0.00
abnormal embryo size Itpr1tm1.1(NCOM)Mfgc HET embryonic day 9.5 0.00
preweaning lethality, incomplete penetrance Itpr1tm1.1(NCOM)Mfgc HOM n/a 0.00
embryonic growth retardation Itpr1tm1.1(NCOM)Mfgc HOM embryonic day 9.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 4  (6/485)  (2/5) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 4  (1/485) N/A
Embryo 4  (1/485)  (5/5) N/A
Eye 4  (1/485)  (2/5) N/A
Foot 4  (1/485) N/A
Forebrain 4  (1/485) N/A
Forelimb 4  (1/485) N/A
Gut 2  (1/50) N/A
Hand 4  (1/485) N/A
Head 4  (5/485) N/A
Heart 4  (1/485)  (2/5) N/A
Hindbrain 4  (6/485) N/A
Hindlimb 4  (1/485) N/A
Liver 4  (1/485) N/A
Lung 4  (1/485) N/A
Mandibular process 4  (1/485) N/A
Maxillary process 4  (1/485) N/A
Midbrain 4  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 4  (1/485) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51) N/A
Skin 4  (1/485)  (2/5) N/A
Spinal cord 2  (1/50) N/A
Tail 4  (1/485) N/A
Tail somite 4  (1/485)  (2/5) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
Gross Morphology Embryo E9.5
2 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Itpr1tm357032(L1L2_Bact_P) Targeting vectors
Itpr1tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Itpr1tm1.1(NCOM)Mfgc Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue

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