Gene: Il2ra

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Name
interleukin 2 receptor, alpha chain
MGI ID
MGI:96549
Synonyms
CD25 IL-2R alpha chain Ly-43 Il2r
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged lymph nodes Il2ratm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased lymphocyte cell number Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 1.08×10-06
decreased eosinophil cell number Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 9.84×10-10
increased heart rate Il2ratm1b(EUCOMM)Wtsi HOM Early adult 4.96×10-06
decreased circulating HDL cholesterol level Il2ratm1b(EUCOMM)Wtsi HOM Early adult 3.17×10-07
decreased circulating serum albumin level Il2ratm1b(EUCOMM)Wtsi HOM Early adult 3.71×10-23
decreased bone mineral density Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 2.49×10-13
increased neutrophil cell number Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 1.92×10-05
decreased circulating alkaline phosphatase level Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 5.59×10-05
decreased circulating glucose level Il2ratm1b(EUCOMM)Wtsi HOM Early adult 4.35×10-05
decreased hematocrit Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 6.71×10-14
decreased heart weight Il2ratm1b(EUCOMM)Wtsi HOM Early adult 2.82×10-08
improved glucose tolerance Il2ratm1b(EUCOMM)Wtsi HOM Early adult 9.43×10-16
decreased circulating total protein level Il2ratm1b(EUCOMM)Wtsi HOM Early adult 4.25×10-05
abnormal duodenum morphology Il2ratm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased mean corpuscular hemoglobin Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 6.89×10-07
decreased mean corpuscular hemoglobin concentration Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 6.01×10-09
decreased body length Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 1.11×10-07
abnormal freezing behavior Il2ratm1b(EUCOMM)Wtsi HOM Early adult 1.90×10-05
hypoactivity Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 3.78×10-05
abnormal spleen morphology Il2ratm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased erythrocyte cell number Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 1.64×10-07
abnormal colon morphology Il2ratm1b(EUCOMM)Wtsi HOM Early adult 0.00
short tibia Il2ratm1b(EUCOMM)Wtsi HOM Early adult 7.58×10-05
abnormal vertebrae morphology Il2ratm1b(EUCOMM)Wtsi HOM Early adult 1.20×10-08
increased circulating phosphate level Il2ratm1b(EUCOMM)Wtsi HOM Early adult 1.87×10-07
decreased bone mineral content Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 8.41×10-06
decreased hemoglobin content Il2ratm1b(EUCOMM)Wtsi HOM   Early adult 8.88×10-16

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
3 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Il2ratm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Il2ratm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Il2ratm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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