Gene: Il2ra

Name
interleukin 2 receptor, alpha chain
MGI ID
MGI:96549
Synonyms
Il2r IL-2R alpha chain Ly-43 CD25
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal colon morphology Il2ratm1b(EUCOMM)Wtsi HOM postnatal 0.00
abnormal behavior Il2ratm1b(EUCOMM)Wtsi HOM postnatal 2.16×10-05
increased heart rate Il2ratm1b(EUCOMM)Wtsi HOM postnatal 4.16×10-05
enlarged lymph nodes Il2ratm1b(EUCOMM)Wtsi HOM postnatal 0.00
decreased circulating cholesterol level Il2ratm1b(EUCOMM)Wtsi HOM postnatal 3.38×10-07
abnormal eye anterior chamber depth Il2ratm1b(EUCOMM)Wtsi HOM postnatal 2.01×10-05
decreased circulating serum albumin level Il2ratm1b(EUCOMM)Wtsi HOM postnatal 9.38×10-08
decreased circulating HDL cholesterol level Il2ratm1b(EUCOMM)Wtsi HOM postnatal 5.32×10-14
decreased circulating glucose level Il2ratm1b(EUCOMM)Wtsi HOM postnatal 6.58×10-09
abnormal spleen morphology Il2ratm1b(EUCOMM)Wtsi HOM postnatal 0.00
decreased heart weight Il2ratm1b(EUCOMM)Wtsi HOM postnatal 2.15×10-09
improved glucose tolerance Il2ratm1b(EUCOMM)Wtsi HOM postnatal 5.34×10-09
increased circulating phosphate level Il2ratm1b(EUCOMM)Wtsi HOM postnatal 1.25×10-07
hypoactivity Il2ratm1b(EUCOMM)Wtsi HOM postnatal 1.57×10-05
abnormal vertebrae morphology Il2ratm1b(EUCOMM)Wtsi HOM postnatal 1.14×10-08
abnormal duodenum morphology Il2ratm1b(EUCOMM)Wtsi HOM postnatal 0.00

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Filtered by: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
3 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Il2ratm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Il2ratm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Il2ratm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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