Gene: Rbpj

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Name
recombination signal binding protein for immunoglobulin kappa J region
MGI ID
MGI:96522
Synonyms
CBF1 Igkrsbp RBP-J kappa RBPjk Igkjrb Rbpsuh
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Rbpjtm1b(EUCOMM)Hmgu HOM   E12.5 0.00
increased circulating bilirubin level Rbpjtm1b(EUCOMM)Hmgu HET Early adult 5.17×10-06
increased grip strength Rbpjtm1b(EUCOMM)Hmgu HET   Early adult 1.78×10-05
increased thigmotaxis Rbpjtm1b(EUCOMM)Hmgu HET   Early adult 8.39×10-05
preweaning lethality, complete penetrance Rbpjtm1b(EUCOMM)Hmgu HOM   Early adult 0.00
hypoactivity Rbpjtm1b(EUCOMM)Hmgu HET Early adult 2.25×10-05
decreased circulating cholesterol level Rbpjtm1b(EUCOMM)Hmgu HET   Early adult 9.67×10-05
decreased circulating HDL cholesterol level Rbpjtm1b(EUCOMM)Hmgu HET   Early adult 5.17×10-06
decreased circulating triglyceride level Rbpjtm1b(EUCOMM)Hmgu HET Early adult 3.22×10-07
decreased bone mineral content Rbpjtm1b(EUCOMM)Hmgu HET Early adult 7.70×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505) Image Only N/A
2  (1/506)  (2/2)  Wholemount images
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61) Image Only N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/505)  (1/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/503) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/503) Image Only N/A
2  (1/505)  (1/2) N/A
2  (1/72)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rbpjtm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Rbpjtm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Rbpjtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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