Genes Phenotypes

Gene: Idh2

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Name
isocitrate dehydrogenase 2 (NADP+), mitochondrial
MGI ID
MGI:96414
Synonyms
Idh-2 IDPm
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (1) Measurements chart (218) All data table (399)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
long tibia Idh2tm1b(EUCOMM)Hmgu HOM Early adult 1.34×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (1/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Heart expression
MA:0000072
digestive system (2)
Large Intestine expression
MA:0000333
endocrine system (1)
Thyroid gland expression
MA:0000129
exocrine system (1)
Prostate gland expression
MA:0000404
nervous system (4)
Hippocampus expression
Striatum expression
Brain expression
MA:0000191
MA:0000891
MA:0000168
postnatal mouse (16)
Eye expression
MA:0000261
reproductive system (3)
Ovary ambiguous
Oviduct expression
MA:0000384
MA:0000385
respiratory system (1)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
trunk (10)
Heart expression
MA:0000072
urinary system (1)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 4  (6/504)  (1/6) N/A
Ear 4  (1/504) N/A
Embryo 4  (1/505)  (6/6) N/A
Eye 4  (1/504)  (2/6) N/A
Foot 4  (1/504) N/A
Forebrain 4  (1/504)  (1/6) N/A
Forelimb 4  (1/504)  (1/6) N/A
Hand 4  (1/503) N/A
Head 4  (5/504)  (5/6) N/A
Heart 4  (1/504)  (2/6) N/A
Hindbrain 4  (6/504)  (1/6) N/A
Hindlimb 4  (1/503)  (1/6) N/A
Liver 4  (1/504) N/A
Lung 4  (1/500) N/A
Mandibular process 4  (1/504) N/A
Maxillary process 4  (1/504) N/A
Midbrain 4  (1/504)  (1/6) N/A
Oral cavity 4  (1/504) N/A
Skin 4  (1/504) N/A
Tail 4  (1/504)  (1/6) N/A
Tail somite 4  (1/504) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
16 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Idh2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Idh2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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