Idh1 | isocitrate dehydrogenase 1 (NADP+), soluble

GeneMGI:96413Synonyms: Idh-1, IDPc, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Nervous system Mortality/aging

15 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetIdh1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetIdh1tm1b(EUCOMM)WtsihomozygoteEarly adult1.29x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Idh1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Idh1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Idh1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Idh1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Idh1tm2e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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