Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased heart weight Idetm1a(EUCOMM)Wtsi HOM Early adult 7.67×10-07
abnormal cranium morphology Idetm1a(EUCOMM)Wtsi HOM Early adult 1.89×10-06
abnormal maxilla morphology Idetm1a(EUCOMM)Wtsi HOM Early adult 1.47×10-05
decreased total body fat amount Idetm1a(EUCOMM)Wtsi HOM Early adult 1.50×10-06
increased circulating amylase level Idetm1a(EUCOMM)Wtsi HOM   Early adult 1.05×10-08
abnormal hair texture Idetm1a(EUCOMM)Wtsi HOM Early adult 4.14×10-05
decreased circulating cholesterol level Idetm1a(EUCOMM)Wtsi HOM   Early adult 5.08×10-06
decreased circulating LDL cholesterol level Idetm1a(EUCOMM)Wtsi HOM   Early adult 3.94×10-05
increased lean body mass Idetm1a(EUCOMM)Wtsi HOM Early adult 1.59×10-06
abnormal behavior Idetm1a(EUCOMM)Wtsi HOM Early adult 8.24×10-05
abnormal incisor morphology Idetm1a(EUCOMM)Wtsi HOM Early adult 9.97×10-07
decreased body weight Idetm1a(EUCOMM)Wtsi HOM   Early adult 3.04×10-09

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583)  (1/2) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No  (1/176) N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (1/583)  (2/2) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Section Images

View all 6 images

No Embryo expression data was found for this gene.

 Associated Images

Histopathology
5 Images
Legacy Phenotype Associated Images

View all 68 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - process of degenerative change Idetm1a(EUCOMM)Wtsi HOM Early adult
Brain - process of degenerative change Idetm1a(EUCOMM)Wtsi HOM Early adult
Brain - MPATH diagnostic term cyst Idetm1a(EUCOMM)Wtsi HOM Early adult
Brain - developmental and structural abnormality Idetm1a(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Idetm47938(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors
Idetm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Idetm47938(L1L2_gt2) Targeting vectors
Idetm47938(L1L2_gt2_Del_LacZ) Targeting vectors

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