Genes Phenotypes

Gene: Ica1

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Name
islet cell autoantigen 1
MGI ID
MGI:96391
Synonyms
ICA69 69kDa
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (10) Measurements chart (149) All data table (301)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged kidney Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
small spleen Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal eye morphology Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased lean body mass Ica1tm1b(EUCOMM)Wtsi HOM Early adult 4.25×10-06
enlarged cecum Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal kidney morphology Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal spleen morphology Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal cecum morphology Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal seminal vesicle morphology Ica1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
decreased total body fat amount Ica1tm1b(EUCOMM)Wtsi HOM Early adult 7.96×10-08

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (1/2)  Section images
Parathyroid gland 2 No  (1/2)  Section images
Parotid gland 2 No  (1/2)  Section images
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584)  (1/2)  Section images
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (2/2)  Section images
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
Unassigned Top Level MA (14)
digestive system (13)
Colon expression
MA:0000335
endocrine system (5)
Adrenal gland expression
MA:0000116
exocrine system (6)
Parotid gland expression
MA:0001585
nervous system (15)
Cerebellum expression
MA:0000198
postnatal mouse (55)
Adrenal gland expression
MA:0000116
reproductive system (7)
Epididymis expression
MA:0000397
respiratory system (8)
Parotid gland expression
MA:0001585
sensory organ (3)
Eye expression
MA:0000261
trunk (35)
Adrenal gland expression
MA:0000116
urinary system (8)
Kidney expression
MA:0000368
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
69 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Ica1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ica1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Ica1tm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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