Gene: Htr3a

Name
5-hydroxytryptamine (serotonin) receptor 3A
MGI ID
MGI:96282
Synonyms
5-HT3 receptor
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (43) Expression & images (0) Disease models (0) Order (2)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Htr3aem1(IMPC)J JAX Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:3m 1.00 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Vitreous HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 0.851 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 0.312 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Htr3aem1(IMPC)J JAX Eye Morphology / Corneal Sclerization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Heart Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0688 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:3m 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Corneal deposits HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:3m 0.171 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:3m 0.0271 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:0m 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Viability Primary Screen / Outcome HOM 43f:45m Supplied as data Success
Htr3aem1(IMPC)J JAX Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Htr3aem1(IMPC)J JAX Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 0.0210 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Iris transilumination HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:0m 0.147 Success
Htr3aem1(IMPC)J JAX Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:3m 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Htr3aem1(IMPC)J JAX Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
4 Images
X-ray: XRay Images Dorso Ventral
4 Images
X-ray: XRay Images Forepaw
4 Images
X-ray: XRay Images Skull Lateral Orientation
4 Images
X-ray: XRay Images Lateral Orientation
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Htr3aem1(IMPC)J Exon Deletion Mice
Htr3atm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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