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Gene: Hoxd8 MGI:96209

Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:

homeobox D8

Synonyms:

Hox-4.3, 4921540P06Rik, Hox-5.4

Order Alleles

IMPC Data Collections

No Body Weight Data
No Embryo Imaging Data
No Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxd8 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Hoxd8 (0 diseases)
Human diseases predicted to be associated with Hoxd8 (169 diseases)

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Hoxd8 by phenotypic similarity.

Disease	Matching phenotypes	Source
Cervical Rib	Cervical ribs	OMIM:117900
Chondrocalcinosis Due To Apatite Crystal Deposition	Costal cartilage calcification, Chondrocalcinosis, Osteoarthritis of the small joints of the hand...	OMIM:118610
Sacral Agenesis With Vertebral Anomalies	Absence of the sacrum, Abnormal vertebral morphology	OMIM:615709
Neurogenic Thoracic Outlet Syndrome	Abnormality of the ribs	ORPHA:100073
Familial Scheuermann Disease	Kyphosis, Abnormal form of the vertebral bodies	ORPHA:3135
Thoracomelic Dysplasia	Bell-shaped thorax, Short ribs	OMIM:273740
Thoracic Dysostosis, Isolated	Pectus excavatum, Bell-shaped thorax, Short ribs	OMIM:187750
Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome	Radioulnar synostosis, Finger syndactyly, Pectus carinatum, Abnormality of the elbow, Abnormality...	ORPHA:3268
Bone Dysplasia, Lethal, Holmgren Type	Bell-shaped thorax, Short ribs, Narrow chest	OMIM:211120
Hypo- And Hypermelanotic Cutaneous Macules-Retarded Growth-Intellectual Disability Syndrome	Abnormality of the ribs	ORPHA:2435
Spondylometaphyseal Dysplasia, Type A4	Metaphyseal sclerosis, Metaphyseal irregularity, Pectus carinatum, Osteoporotic metatarsal, Osteo...	OMIM:609052
Spondylocostal Dysostosis 3, Autosomal Recessive	Scoliosis, Supernumerary vertebral ossification centers, Kyphosis, Rib fusion, Slender finger, Ve...	OMIM:609813
Kyphomelic Dysplasia	Anterior rib cupping, Lateral clavicle hook, Short thorax, Narrow chest, Bowing of the long bones...	ORPHA:1801
Acrodysplasia Scoliosis	Scoliosis, Brachydactyly, Vertebral segmentation defect, Spina bifida occulta	ORPHA:2956
Jeune Syndrome	Abnormal clavicle morphology, Short thorax, Postaxial hand polydactyly, Toe syndactyly, Narrow ch...	ORPHA:474
Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly	Lateral clavicle hook, Narrow chest, Bell-shaped thorax, Horizontal ribs, Postaxial polydactyly, ...	OMIM:615633
Thoracolaryngopelvic Dysplasia	Hypoplastic pelvis, Bell-shaped thorax, Horizontal ribs, Short ribs, Hypoplastic iliac wing, Irre...	OMIM:187760
Mesomelic Dysplasia, Kantaputra Type	Cubitus valgus, Camptodactyly of finger, Tarsal synostosis, Abnormality of the ankles, Synostosis...	ORPHA:1836
Spondylometaphyseal Dysplasia, A4 Type	Coxa vara, Flared, irregular rib ends, Short palm	ORPHA:168555
Thin Ribs-Tubular Bones-Dysmorphism Syndrome	Abnormality of the ribs, Slender long bone, Abnormality of pelvic girdle bone morphology	ORPHA:1506
Congenital Pseudoarthrosis Of The Clavicle	Cervical ribs, Osteoarthritis, Congenital pseudoarthrosis of the clavicle	ORPHA:66630
Spondyloepimetaphyseal Dysplasia, Irapa Type	Genu valgum, Upper limb undergrowth, Short metatarsal, Hypoplastic pelvis, Pectus carinatum, Syno...	ORPHA:93351
Spondyloepimetaphyseal Dysplasia, Borochowitz-Cormier-Daire Type	Limited elbow extension, Thoracic hypoplasia, Irregular epiphyses, Narrow iliac wing, Hypoplastic...	OMIM:608728
Acrocapitofemoral Dysplasia	Narrow chest, Flared iliac wing, Short distal phalanx of finger, Cone-shaped epiphysis of the 1st...	OMIM:607778
Hypogonadism, Male, With Mental Retardation And Skeletal Anomalies	Superior rib anomalies	OMIM:307500
Craniodiaphyseal Dysplasia	Abnormality of the ribs, Diaphyseal thickening	ORPHA:1513
Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies	Abnormality of the ribs, Pectus excavatum, Hypoplastic distal segments of scapulae	OMIM:602196
Thanatophoric Dysplasia, Type Ii	Narrow chest, Metaphyseal irregularity, Hypoplastic ilia, Wide-cupped costochondral junctions, Sh...	OMIM:187601
Endosteal Hyperostosis, Worth Type	Abnormality of the ribs, Clavicular sclerosis, Diaphyseal thickening	ORPHA:2790
Spondyloepimetaphyseal Dysplasia, Irapa Type	Limited elbow extension, Genu valgum, Upper limb undergrowth, Short metatarsal, Pectus carinatum,...	OMIM:271650
Hyperparathyroidism, Transient Neonatal	Thin ribs, Femoral bowing, Short ribs, Narrow chest	OMIM:618188
Heart Defects-Limb Shortening Syndrome	Abnormality of the ribs, Abnormality of the metaphysis, Narrow chest	ORPHA:1354
Metaphyseal Chondrodysplasia, Schmid Type	Metaphyseal irregularity, Bowing of the legs, Femoral bowing, Hip dysplasia, Ulnar metaphyseal ir...	ORPHA:174
Schneckenbecken Dysplasia	Anterior rib cupping, Lateral clavicle hook, Advanced tarsal ossification, Narrow chest, Metaphys...	OMIM:269250
Spondylocostal Dysostosis 4, Autosomal Recessive	Short thorax, Rib fusion, Vertebral fusion, Abnormality of the ribs, Block vertebrae, Missing ribs	OMIM:613686
Poland Syndrome	Sprengel anomaly, Rib fusion, Short ribs, Unilateral brachydactyly, Syndactyly, Unilateral oligod...	OMIM:173800
Grant Syndrome	Wormian bones, Abnormality of the glenoid fossa, Narrow chest, Sprengel anomaly, Bowing of the lo...	ORPHA:2097
Spondylomegaepiphyseal Dysplasia With Upper Limb Mesomelia, Punctate Calcifications, And Deafness	Distal ulnar epiphyseal stippling, Broad toe, Delayed ossification of carpal bones, Hypoplastic i...	OMIM:609616
Metatropic Dysplasia	Camptodactyly of finger, Narrow chest, Halberd-shaped pelvis, Long thorax, Coarse metaphyseal tra...	ORPHA:2635
Cortical Defects, Wormian Bones, And Dentinogenesis Imperfecta	Limited elbow extension, Delayed closure of the anterior fontanelle, Wormian bones, Thin ribs, As...	OMIM:604922
Thoracic Outlet Syndrome	Abnormality of the ribs	ORPHA:97330
Sprengel Deformity	Rib segmentation abnormalities, Sprengel anomaly	OMIM:184400
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type	Narrow chest, Hypoplastic ilia, Metaphyseal cupping, Hypoplastic pubic bone, Short ribs, Thin rib...	OMIM:151210
Holt-Oram Syndrome	Abnormal clavicle morphology, Broad thumb, Radioulnar synostosis, Finger syndactyly, Split hand, ...	ORPHA:392
Spondylocostal Dysostosis 5	Posterior rib fusion, Pectus carinatum, Vertebral fusion, Supernumerary ribs, Missing ribs	OMIM:122600
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3	Dislocated radial head, Multiple joint dislocation, Metaphyseal irregularity, Carpal bone hypopla...	OMIM:618395
Spondyloepimetaphyseal Dysplasia, Missouri Type	Radial bowing, Limited elbow extension, Flared iliac wing, Metaphyseal cupping, Tibial bowing, Co...	OMIM:602111
Cloverleaf Skull-Multiple Congenital Anomalies Syndrome	Abnormal clavicle morphology, Narrow chest, Abnormality of epiphysis morphology, Bowing of the lo...	ORPHA:93267
Osteogenesis Imperfecta, Type Ix	Wormian bones, Pectus carinatum, Pectus excavatum, Beaded ribs, Short lower limbs	OMIM:259440
Microcephaly, Short Stature, And Limb Abnormalities	Dislocated radial head, Hypoplasia of the radius, Radioulnar synostosis, Patellar aplasia, Short ...	OMIM:617604
Hemangiomas, Cavernous, Of Face And Supraumbilical Midline Raphe	Supraumbilical raphe, Bifid sternum	OMIM:140850
Metaphyseal Dysostosis, Mental Retardation, And Conductive Deafness	Metaphyseal widening, Genu valgum, Metaphyseal irregularity, Broad phalanx, Carpal bone hypoplasi...	OMIM:250420
Dyggve-Melchior-Clausen Disease	Iliac crest serration, Limited elbow extension, Short thorax, Genu valgum, Pectus carinatum, Shor...	ORPHA:239
Spondylocostal Dysostosis 2, Autosomal Recessive	Rib fusion	OMIM:608681
10Q22.3Q23.3 Microduplication Syndrome	Abnormality of the ribs, Abnormal clavicle morphology	ORPHA:276422
Juberg-Hayward Syndrome	Hypoplasia of the radius, Toe syndactyly, Abnormality of finger, Radioulnar synostosis, Abnormali...	ORPHA:2319
Achondrogenesis, Type Ii	Broad long bones, Horizontal ribs, Hypoplastic iliac wing, Short ribs, Short long bone, Short tub...	OMIM:200610
Fibrochondrogenesis 1	Camptodactyly, Hypoplastic ischia, Narrow greater sciatic notch, Thin clavicles, Short long bone,...	OMIM:228520
Diastrophic Dwarfism	Abnormal clavicle morphology, Hip dysplasia, Camptodactyly of finger, Elbow dislocation, Abnormal...	ORPHA:628
Autosomal Dominant Spondylocostal Dysostosis	Abnormality of the ribs, Short thorax, Posterior rib fusion, Missing ribs	ORPHA:1797
Short-Rib Thoracic Dysplasia 19 With Or Without Polydactyly	Lateral clavicle hook, Hypoplasia of the radius, Narrow chest, Thoracic hypoplasia, Hypoplastic i...	OMIM:617895
Femoral-Facial Syndrome	Hip dysplasia, Short femur, Radioulnar synostosis, Sprengel anomaly, Preaxial foot polydactyly, R...	ORPHA:1988
Spondylometaphyseal Dysplasia With Cone-Rod Dystrophy	Metaphyseal irregularity, Hypoplastic inferior ilia, Short finger, Metaphyseal cupping, Tibial bo...	OMIM:608940
Microcephalic Primordial Dwarfism, Toriello Type	Abnormality of the ribs, Brachydactyly, Abnormality of epiphysis morphology	ORPHA:2643
Isolated Klippel-Feil Syndrome	Sprengel anomaly, Cervical C2/C3 vertebral fusion, Abnormal vertebral segmentation and fusion, Ab...	ORPHA:2345
Hypophosphatasia	Craniosynostosis, Narrow chest, Bowing of the long bones, Abnormality of the metaphysis, Abnormal...	ORPHA:436
Mosaic Trisomy 14	Abnormality of the ribs, Camptodactyly of finger, Narrow chest	ORPHA:1703
Cat-Eye Syndrome	Abnormality of the ribs, Hip dysplasia	ORPHA:195
Achondrogenesis Type 1B	Abnormality of the ribs, Short thorax, Narrow chest, Short foot	ORPHA:93298
Chondrodysplasia With Platyspondyly, Distinctive Brachydactyly, Hydrocephaly, And Microphthalmia	Metaphyseal cupping of metacarpals, Metaphyseal cupping, Hypoplastic iliac wing, Thin ribs, Metap...	OMIM:300863
White Forelock With Malformations	Abnormality of the ribs, Sprengel anomaly, Clinodactyly of the 5th finger, Finger syndactyly	ORPHA:2475
Fibrochondrogenesis	Camptodactyly of finger, Broad ribs, Narrow chest, Hypoplastic scapulae, Bell-shaped thorax, Shor...	ORPHA:2021
Achondrogenesis, Type Ia	Hypoplasia of the radius, Hypoplastic scapulae, Beaded ribs, Short ribs, Broad clavicles, Hypopla...	OMIM:200600
Microcephaly-Cervical Spine Fusion Anomalies Syndrome	Abnormal clavicle morphology, Pectus excavatum, Abnormal hip bone morphology, Abnormality of the ...	ORPHA:2522
Intellectual Disability-Polydactyly-Uncombable Hair Syndrome	Aplasia/Hypoplasia of fingers, Postaxial hand polydactyly, Toe syndactyly, Abnormality of epiphys...	ORPHA:3082
Becker Nevus Syndrome	Abnormality of tibia morphology, Pectus carinatum, Pectus excavatum, Rib fusion, Supernumerary ribs	ORPHA:64755
Spondylometaphyseal Dysplasia, Algerian Type	Anterior rib cupping, Genu valgum, Hypoplastic pelvis, Carpal bone hypoplasia, Flared femoral met...	OMIM:184253
Melnick-Needles Syndrome	Short thorax, Narrow chest, Bowing of the long bones, Short distal phalanx of finger, Osteolytic ...	ORPHA:2484
Lethal Congenital Contracture Syndrome Type 1	Abnormality of the ribs, Abnormality of the elbow, Slender long bone, Abnormal hip bone morphology	ORPHA:1486
Craniosynostosis, Herrmann-Opitz Type	Craniosynostosis, Finger syndactyly, Split hand, Abnormality of the ribs, Brachydactyly	ORPHA:2145
Cerebral-Cerebellar-Coloboma Syndrome, X-Linked	Abnormality of the ribs	OMIM:300864
Mucolipidosis Iii Alpha/Beta	Irregular carpal bones, Craniosynostosis, Broad ribs, Split hand, Carpal bone hypoplasia, Short r...	OMIM:252600
Mayer-Rokitansky-Küster-Hauser Syndrome Type 2	Abnormality of the ribs	ORPHA:2578
Kenny-Caffey Syndrome, Type 1	Delayed closure of the anterior fontanelle, Short palm, Thin ribs, Slender long bone, Small hand,...	OMIM:244460
Craniofaciofrontodigital Syndrome	Abnormal thumb morphology, Narrow chest, Abnormal hip bone morphology, Abnormality of the ribs, A...	ORPHA:363705
Rhizomelic Dysplasia, Scoliosis, And Retinitis Pigmentosa	Broad ribs, Short humerus, Short ribs, Short clavicles, Short femoral neck, Prominent deltoid tub...	OMIM:610319
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome	Radial bowing, Bowing of the long bones, Tibial bowing, Lower limb undergrowth, Abnormality of th...	ORPHA:3035
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly	Lateral clavicle hook, Absent tibia, Thoracic hypoplasia, Preaxial polydactyly, Horizontal ribs, ...	OMIM:613091
Eiken Syndrome	Broad ribs, Delayed ossification of carpal bones, Broad metatarsal, Short middle phalanx of finge...	OMIM:600002
Spondylometaphyseal Dysplasia, Sedaghatian Type	Short phalanx of finger, Narrow chest, Flared iliac wing, Metaphyseal irregularity, Iliac crest s...	OMIM:250220
Klippel-Feil Syndrome 1, Autosomal Dominant	Abnormality of limb bone morphology, Sprengel anomaly, Cervical C2/C3 vertebral fusion, Abnormal ...	OMIM:118100
Kyphomelic Dysplasia	Anterior rib cupping, Radial bowing, Lateral clavicle hook, Short femur, Bowed humerus, Thoracic ...	OMIM:211350
Ellis-Van Creveld Syndrome	Genu valgum, Postaxial hand polydactyly, Narrow chest, Pectus carinatum, Horizontal ribs, Hypopla...	OMIM:225500
Van Den Ende-Gupta Syndrome	Distal ulnar hypoplasia, Dislocated radial head, Lateral clavicle hook, Craniosynostosis, Camptod...	OMIM:600920
Cooper-Jabs Syndrome	Camptodactyly of finger, Abnormal hip bone morphology, Abnormality of the ribs, Proximal placemen...	ORPHA:1488
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome	Postaxial hand polydactyly, Broad ribs, Abnormal sternum morphology, Short ribs, Abnormality of t...	ORPHA:2519
Phaver Syndrome	Camptodactyly of finger, Broad thumb, Radioulnar synostosis, Broad hallux phalanx, Pterygium, Sho...	ORPHA:2876
Cenani-Lenz Syndrome	Oligodactyly, Hypoplasia of the radius, Toe syndactyly, Radioulnar synostosis, Elbow dislocation,...	ORPHA:3258
Renpenning Syndrome	Abnormal thumb morphology, Pectus excavatum, Sprengel anomaly, Abnormality of the ribs, Clinodact...	ORPHA:3242
Hydrocephalus-Costovertebral Dysplasia-Sprengel Anomaly Syndrome	Abnormality of the ribs, Sprengel anomaly, Brachydactyly, Sandal gap	ORPHA:2180
Antley-Bixler Syndrome	Camptodactyly of finger, Craniosynostosis, Narrow chest, Elbow ankylosis, Delayed cranial suture ...	ORPHA:83
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome	Abnormality of the ribs, Abnormality of the humeroulnar joint	ORPHA:2234
Imperforate Oropharynx-Costovertebral Anomalies Syndrome	Abnormality of the ribs, Clinodactyly of the 5th finger, Missing ribs, Arachnodactyly	ORPHA:2759
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies	Abnormality of the ribs, Sprengel anomaly	OMIM:601076
Nestor-Guillermo Progeria Syndrome	Osteolytic defects of the distal phalanges of the hand, Delayed closure of the anterior fontanell...	OMIM:614008
Spondyloepimetaphyseal Dysplasia, X-Linked	Short phalanx of finger, Metaphyseal irregularity, Flared iliac wing, Broad long bone diaphyses, ...	OMIM:300106
Microcephaly-Micromelia Syndrome	Oligodactyly, Humeroradial synostosis, Craniosynostosis, Narrow chest, Forearm undergrowth, Absen...	OMIM:251230
Congenital Osteogenesis Imperfecta-Microcephaly-Cataracts Syndrome	Abnormality of the ribs	ORPHA:2772
Cleidocranial Dysplasia	Wormian bones, Genu valgum, Abnormal thumb morphology, Narrow chest, Abnormality of epiphysis mor...	ORPHA:1452
Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly	Lateral clavicle hook, Hand polydactyly, Short phalanx of finger, Narrow chest, Metaphyseal irreg...	OMIM:208500
Mucopolysaccharidosis Type 4	Genu valgum, Short thorax, Abnormality of epiphysis morphology, Pectus carinatum, Bowing of the l...	ORPHA:582
Septopreoptic Holoprosencephaly	Abnormality of the ribs	ORPHA:280195
Laryngotracheoesophageal Cleft Type 4	Abnormality of the ribs	ORPHA:93941
Spondylometaphyseal Dysplasia, Sedaghatian Type	Metaphyseal chondrodysplasia, Narrow chest, Short palm, Cone-shaped epiphysis, Iliac crest serrat...	ORPHA:93317
X-Linked Hypophosphatemia	Genu valgum, Craniosynostosis, Sacroiliac joint synovitis, Flared iliac wing, Abnormality of epip...	ORPHA:89936
Congenital Disorder Of Glycosylation, Type Iig	Abnormality of the ribs, Camptodactyly, Small hand, Short foot	OMIM:611209
Pyknoachondrogenesis	Aplastic pubic bones, Short thorax, Short iliac bones, Enlarged thorax, Horizontal ribs, Abnormal...	ORPHA:3003
Intellectual Disability-Myopathy-Short Stature-Endocrine Defect Syndrome	Abnormality of the ribs, Clinodactyly of the 5th finger, Abnormal hip bone morphology, Pectus car...	ORPHA:3068
Oculocerebrocutaneous Syndrome	Hand polydactyly, Congenital hip dislocation, Finger syndactyly, Short distal phalanx of finger, ...	ORPHA:1647
Poland Syndrome	Absent hand, Abnormal sternum morphology, Split hand, Unilateral brachydactyly, Abnormality of th...	ORPHA:2911
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome	Preaxial hand polydactyly, Abnormal thumb morphology, Short distal phalanx of finger, Short thumb...	ORPHA:1120
Autosomal Recessive Spondylocostal Dysostosis	Camptodactyly of finger, Short thorax, Finger syndactyly, Rib segmentation abnormalities, Rib fus...	ORPHA:2311
Holzgreve Syndrome	Abnormality of the ribs, Abnormality of the ulna, Hand polydactyly, Abnormality of the metacarpal...	ORPHA:2167
Campomelia, Cumming Type	Bowing of the long bones, Abnormal thorax morphology, Clubbing of toes, Abnormality of the ribs, ...	ORPHA:1318
Cole-Carpenter Syndrome	Wormian bones, Bowing of the long bones, Crumpled long bones, Abnormality of the metaphysis, Abno...	ORPHA:2050
Otopalatodigital Syndrome Type 2	Short hallux, Camptodactyly of finger, Tarsal synostosis, Narrow chest, Elbow dislocation, Flared...	ORPHA:90652
Trisomy 13	Postaxial hand polydactyly, Narrow chest, Abnormality of the ribs, Abnormality of pelvic girdle b...	ORPHA:3378
Spondylometaphyseal Dysplasia-Cone-Rod Dystrophy Syndrome	Bowing of the long bones, Metaphyseal cupping, Limited elbow movement, Abnormality of the ribs, S...	ORPHA:85167
Cartilage-Hair Hypoplasia	Limited elbow extension, Short thorax, Metaphyseal chondrodysplasia, Narrow chest, Abnormality of...	ORPHA:175
Prune Belly Syndrome	Abnormality of the ribs, Pectus excavatum, Congenital hip dislocation	ORPHA:2970
Ulna And Fibula, Absence Of, With Severe Limb Deficiency	Aplastic pubic bones, Split hand, Phocomelia, Elbow flexion contracture, Barrel-shaped chest, Fem...	OMIM:276820
Trisomy 1Q	Camptodactyly of finger, Short thorax, Preaxial hand polydactyly, Toe syndactyly, Abnormality of ...	ORPHA:261344
Axial Mesodermal Dysplasia Spectrum	Abnormality of the ribs, Abnormality of pelvic girdle bone morphology, Abnormality of the knee, M...	ORPHA:1834
Multiple Pterygium-Malignant Hyperthermia Syndrome	Camptodactyly of finger, Finger syndactyly, Pectus excavatum, Metatarsus adductus, Ulnar deviatio...	ORPHA:2215
Familial Osteodysplasia, Anderson Type	Elbow dislocation, Aplasia/hypoplasia of the femur, Abnormality of the ribs, Aplastic clavicle, C...	ORPHA:2769
Congenital Adrenal Hyperplasia Due To Cytochrome P450 Oxidoreductase Deficiency	Craniosynostosis, Tarsal synostosis, Narrow chest, Camptodactyly, Abnormality of the ribs, Elbow ...	ORPHA:95699
Autosomal Dominant Popliteal Pterygium Syndrome	Toe syndactyly, Finger syndactyly, Split hand, Abnormality of the ribs, Popliteal pterygium	ORPHA:1300
Tetraamelia-Multiple Malformations Syndrome	Abnormality of the ribs, Aplasia/Hypoplasia involving the pelvis, Missing ribs	ORPHA:3301
Radio-Renal Syndrome	Hypoplasia of the radius, Abnormality of the elbow, Abnormality of the ribs, Brachydactyly, Short...	ORPHA:3015
Ifap Syndrome 1, With Or Without Bresheck Syndrome	Abnormality of the ribs, Postaxial hand polydactyly, Hip dislocation, Unilateral chest hypoplasia	OMIM:308205
Mosaic Trisomy 8	Camptodactyly of finger, Narrow chest, Patellar aplasia, Abnormality of the ribs, Clinodactyly of...	ORPHA:96061
Schwartz-Jampel Syndrome	Hip dysplasia, Wormian bones, Genu valgum, Protrusio acetabuli, Elbow dislocation, Pectus carinat...	ORPHA:800
Fibrous Dysplasia Of Bone	Abnormal clavicle morphology, Abnormality of tibia morphology, Abnormality of femur morphology, A...	ORPHA:249
Aspergillosis	Abnormality of the ribs, Abnormality of long bone morphology	ORPHA:1163
Alagille Syndrome	Abnormality of the ribs, Clinodactyly of the 5th finger, Hypoplasia of the ulna, Short distal pha...	ORPHA:52
Vacterl/Vater Association	Abnormality of the ribs, Preaxial hand polydactyly, Aplasia/Hypoplasia of the radius, Finger synd...	ORPHA:887
Osteogenesis Imperfecta	Wormian bones, Abnormality of long bone morphology, Abnormality of tibia morphology, Narrow chest...	ORPHA:666
Hurler Syndrome	Abnormal clavicle morphology, Camptodactyly of finger, Abnormality of epiphysis morphology, Abnor...	ORPHA:93473
Myhre Syndrome	Large iliac wing, Abnormality of epiphysis morphology, Abnormality of the pubic bone, Abnormality...	ORPHA:2588
Ear-Patella-Short Stature Syndrome	Camptodactyly of finger, Craniosynostosis, Elbow dislocation, Abnormality of epiphysis morphology...	ORPHA:2554
Dextrocardia	Abnormality of the ribs, Congenital hip dislocation	ORPHA:1666
Camptodactyly Syndrome, Guadalajara Type 3	Small hand, Short foot, Abnormality of the ribs, Thickened cortex of long bones, Broad femoral neck	ORPHA:488434
Ulbright-Hodes Syndrome	Hypoplasia of the radius, Humeroradial synostosis, Short sternum, Short ribs, Short humerus, Thin...	ORPHA:3404
Trisomy 18	Camptodactyly of finger, Postaxial hand polydactyly, Abnormal hip bone morphology, Abnormality of...	ORPHA:3380
Monosomy 9Q22.3	Abnormality of the ribs, Pectus excavatum, Metopic synostosis, Polydactyly	ORPHA:77301
Simpson-Golabi-Behmel Syndrome	Camptodactyly of finger, Short toe, Postaxial hand polydactyly, Broad thumb, Congenital hip dislo...	ORPHA:373
Hereditary Acrokeratotic Poikiloderma	Camptodactyly of finger, Finger syndactyly, Abnormality of the metacarpal bones, Abnormal hip bon...	ORPHA:2907
Mucopolysaccharidosis Type 3	Hip dysplasia, Genu valgum, Abnormal clavicle morphology, Avascular necrosis of the capital femor...	ORPHA:581
Smith-Lemli-Opitz Syndrome	Postaxial hand polydactyly, Finger syndactyly, Split hand, 2-3 toe syndactyly, Aplasia/Hypoplasia...	ORPHA:818
Autosomal Recessive Malignant Osteopetrosis	Craniosynostosis, Narrow chest, Abnormality of epiphysis morphology, Bowing of the long bones, Ab...	ORPHA:667
Kindler Epidermolysis Bullosa	Short 4th metacarpal, Camptodactyly of finger, Finger syndactyly, Short 5th metacarpal, Abnormali...	ORPHA:2908
Vater/Vacterl Association	Hypoplasia of the radius, Radioulnar synostosis, Abnormal sternum morphology, Preaxial polydactyl...	OMIM:192350
Pagod Syndrome	Abnormality of the ribs, Abnormal clavicle morphology	ORPHA:991
Monosomy 9P	Abnormality of the ribs, Proximal placement of thumb, Postaxial hand polydactyly, Abnormality of ...	ORPHA:261112
Oculocerebrorenal Syndrome Of Lowe	Genu valgum, Joint swelling, Abnormality of epiphysis morphology, Abnormality of the metaphysis, ...	ORPHA:534
Townes-Brocks Syndrome	Preaxial hand polydactyly, Broad thumb, Toe syndactyly, Broad hallux phalanx, Partial duplication...	ORPHA:857
Alagille Syndrome 1	Abnormality of the ribs, Hypoplasia of the ulna, Short distal phalanx of finger	OMIM:118450
Charge Syndrome	Abnormality of tibia morphology, Abnormality of the ribs, Clinodactyly of the 5th finger, Brachyd...	ORPHA:138
Charge Syndrome	Hand polydactyly, Down-sloping shoulders, Hypoplasia of the ulna, Absent radius, Hand monodactyly...	OMIM:214800

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxd8

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxd8.

No publications found that use IMPC mice or data for Hoxd8.

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MGI Allele	Allele Type	Produced
Hoxd8^{tm459029(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}		Targeting vectors

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