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Gene: Hoxd8 MGI:96209

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
homeobox D8
Synonyms:
Hox-5.4,  4921540P06Rik,  Hox-4.3

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxd8 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Hoxd8 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Cervical Rib
Cervical ribs OMIM:117900
Neurogenic Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:100073
Short-Rib Thoracic Dysplasia 17 With Or Without Polydactyly
Narrow chest, Postaxial foot polydactyly, Acetabular spurs, Horizontal ribs, Short ribs, Brachyda... OMIM:617405
Thoracomelic Dysplasia
Bell-shaped thorax, Short ribs OMIM:273740
Thoracic Dysostosis, Isolated
Pectus excavatum, Bell-shaped thorax, Short ribs OMIM:187750
Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome
Pectus carinatum, Finger syndactyly, Radioulnar synostosis, Abnormal rib morphology, Clinodactyly... ORPHA:3268
Hypo- And Hypermelanotic Cutaneous Macules-Retarded Growth-Intellectual Disability Syndrome
Abnormal rib morphology ORPHA:2435
Spondylometaphyseal Dysplasia, Type A4
Pectus carinatum, Irregular patellae, Hypoplasia of the capital femoral epiphysis, Metaphyseal sc... OMIM:609052
Thoracolaryngopelvic Dysplasia
Hypoplastic iliac wing, Hypoplastic pelvis, Bell-shaped thorax, Horizontal ribs, Short ribs, Meta... OMIM:187760
Kyphomelic Dysplasia
Narrow chest, Undulate ribs, Missing ribs, Bowing of the long bones, Anterior rib cupping, Short ... ORPHA:1801
Acrodysplasia Scoliosis
Spina bifida occulta, Scoliosis, Brachydactyly, Vertebral segmentation defect ORPHA:2956
Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly
Narrow chest, Thoracic dysplasia, Bell-shaped thorax, Horizontal ribs, Postaxial polydactyly, Bra... OMIM:615633
Hypersulfaturia
Costochondral pain OMIM:620372
Jeune Syndrome
Abnormal pelvic girdle bone morphology, Toe syndactyly, Postaxial foot polydactyly, Cone-shaped e... ORPHA:474
Mesomelic Dysplasia, Kantaputra Type
Ulnar deviation of finger, Abnormality of the ankle, Synostosis of carpal bones, Camptodactyly of... ORPHA:1836
Thin Ribs-Tubular Bones-Dysmorphism Syndrome
Abnormal pelvic girdle bone morphology, Slender long bone, Abnormal rib morphology ORPHA:1506
Congenital Pseudoarthrosis Of The Clavicle
Congenital pseudoarthrosis of the clavicle, Osteoarthritis, Cervical ribs ORPHA:66630
Spondylometaphyseal Dysplasia, A4 Type
Coxa vara, Short palm, Flared, irregular rib ends ORPHA:168555
Fibrochondrogenesis 2
Hypoplastic ilia, Metaphyseal cupping, Thoracic hypoplasia, Bell-shaped thorax, Short ribs, Cuppe... OMIM:614524
Spondyloepimetaphyseal Dysplasia, Irapa Type
Pectus carinatum, Synostosis of carpal bones, Abnormal epiphysis morphology, Abnormal joint morph... ORPHA:93351
Metatropic Dysplasia
Epiphyseal dysplasia, Caudal appendage, Genu valgum, Flat acetabular roof, Dumbbell-shaped metaph... OMIM:156530
Hypogonadism, Male, With Impaired Intellectual Development And Skeletal Anomalies
Superior rib anomalies OMIM:307500
Craniodiaphyseal Dysplasia
Diaphyseal undertubulation, Abnormal rib morphology ORPHA:1513
Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies
Pectus excavatum, Hypoplastic distal segments of scapulae, Abnormal rib morphology OMIM:602196
Heart Defects-Limb Shortening Syndrome
Narrow chest, Abnormal metaphysis morphology, Abnormal rib morphology ORPHA:1354
Spondyloepimetaphyseal Dysplasia, Borochowitz-Cormier-Daire Type
Metaphyseal spurs, Posterior rib cupping, Thoracic hypoplasia, Irregular epiphyses, Small epiphys... OMIM:608728
Endosteal Hyperostosis, Worth Type
Clavicular sclerosis, Diaphyseal undertubulation, Abnormal rib morphology ORPHA:2790
Metaphyseal Chondrodysplasia, Schmid Type
Radial metaphyseal irregularity, Anterior rib cupping, Genu varum, Femoral bowing, Short long bon... ORPHA:174
Axial Spondylometaphyseal Dysplasia
Abnormal ilium morphology, Hypoplastic iliac wing, Abnormal metacarpal morphology, Flat acetabula... ORPHA:168549
Grant Syndrome
Abnormality of the glenoid fossa, Abnormal pelvic girdle bone morphology, Narrow chest, Joint dis... ORPHA:2097
Poland Syndrome
Short ribs, Rib fusion, Unilateral oligodactyly, Sprengel anomaly, Unilateral brachydactyly, Synd... OMIM:173800
Spondylocostal Dysostosis 3, Autosomal Recessive
Rib fusion, Slender finger, Contracture of the proximal interphalangeal joint of the 2nd finger OMIM:609813
Spondylomegaepiphyseal Dysplasia With Upper Limb Mesomelia, Punctate Calcifications, And Deafness
Hypoplastic iliac wing, Enlarged epiphyses of the phalanges of the hand, Distal ulnar epiphyseal ... OMIM:609616
Hemangiomas, Cavernous, Of Face And Supraumbilical Midline Raphe
Bifid sternum, Supraumbilical raphe OMIM:140850
Holt-Oram Syndrome
Broad thumb, Aplasia/Hypoplasia of the radius, Finger syndactyly, Absent thumb, Abnormal clavicle... ORPHA:392
Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:97330
Metatropic Dysplasia
Narrow chest, Coarse metaphyseal trabecularization, Camptodactyly of finger, Halberd-shaped pelvi... ORPHA:2635
Sprengel Deformity
Sprengel anomaly, Rib segmentation abnormalities OMIM:184400
Spondylocostal Dysostosis 5
Pectus carinatum, Missing ribs, Supernumerary ribs, Vertebral fusion, Posterior rib fusion OMIM:122600
Spondyloepimetaphyseal Dysplasia, Missouri Type
Metaphyseal cupping, Radial bowing, Flared metaphysis, Small epiphyses, Femoral bowing, Limited e... OMIM:602111
Osteogenesis Imperfecta, Type Ix
Pectus carinatum, Multiple rib fractures, Wormian bones, Pectus excavatum, Short lower limbs OMIM:259440
Spondylocostal Dysostosis 2, Autosomal Recessive
Rib fusion OMIM:608681
Cloverleaf Skull-Multiple Congenital Anomalies Syndrome
Narrow chest, Abnormal epiphysis morphology, Abnormal clavicle morphology, Abnormal metaphysis mo... ORPHA:93267
Metaphyseal Dysostosis, Impaired Intellectual Development, And Conductive Deafness
Metaphyseal cupping, Flat glenoid fossa, Irregular iliac crest, Irregular chondrocostal junctions... OMIM:250420
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3
Thin ribs, Multiple joint dislocation, Short femoral neck, Knee dislocation, Carpal bone hypoplas... OMIM:618395
10Q22.3Q23.3 Microduplication Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:276422
Diastrophic Dysplasia
Ulnar deviation of finger, Joint dislocation, Elbow dislocation, Abnormal epiphysis morphology, S... ORPHA:628
Dyggve-Melchior-Clausen Disease
Epiphyseal dysplasia, Genu valgum, Horizontal inferior border of scapula, Metaphyseal dysplasia, ... ORPHA:239
Juberg-Hayward Syndrome
Toe syndactyly, Short thumb, Abnormality of the wrist, Radioulnar synostosis, Abnormal metacarpal... ORPHA:2319
Acrocapitofemoral Dysplasia
Short tibia, Radial bowing, Hypoplastic iliac wing, Dysplasia of the femoral head, Cone-shaped ep... OMIM:607778
Fibrochondrogenesis 1
Thin ribs, Hypoplastic scapulae, Joint contracture of the hand, Small hand, Broad long bones, Bro... OMIM:228520
Short-Rib Thoracic Dysplasia 19 With Or Without Polydactyly
Hypoplastic ilia, Narrow chest, Thoracic hypoplasia, Lateral clavicle hook, Horizontal ribs, Shor... OMIM:617895
Microcephalic Primordial Dwarfism, Toriello Type
Abnormal epiphysis morphology, Brachydactyly, Abnormal rib morphology ORPHA:2643
Autosomal Dominant Spondylocostal Dysostosis
Missing ribs, Posterior rib fusion, Short thorax, Abnormal rib morphology ORPHA:1797
Osteogenesis Imperfecta, Type Ii
Thin ribs, Abnormal pelvic girdle bone morphology, Thoracic hypoplasia, Broad long bones, Bell-sh... OMIM:166210
Femoral-Facial Syndrome
Aplasia/Hypoplasia of the tibia, Abnormal pelvic girdle bone morphology, Abnormal rib morphology,... ORPHA:1988
Mosaic Trisomy 14
Narrow chest, Abnormal rib morphology, Camptodactyly of finger ORPHA:1703
Hypophosphatasia
Narrow chest, Bowing of the long bones, Abnormal rib morphology, Craniosynostosis, Abnormal metap... ORPHA:436
Cat-Eye Syndrome
Hip dysplasia, Abnormal rib morphology ORPHA:195
Spondylometaphyseal Dysplasia, Algerian Type
Hypoplasia of proximal radius, Short tubular bones of the hand, Flared femoral metaphysis, Genu v... OMIM:184253
Isolated Klippel-Feil Syndrome
Abnormal shoulder morphology, Cervical C2/C3 vertebral fusion, Sprengel anomaly, Abnormal rib mor... ORPHA:2345
Becker Nevus Syndrome
Pectus carinatum, Abnormal tibia morphology, Supernumerary ribs, Rib fusion, Pectus excavatum ORPHA:64755
Intellectual Disability-Polydactyly-Uncombable Hair Syndrome
Aplasia/Hypoplasia of fingers, Pectus carinatum, Toe syndactyly, Abnormal epiphysis morphology, M... ORPHA:3082
White Forelock With Malformations
Clinodactyly of the 5th finger, Sprengel anomaly, Finger syndactyly, Abnormal rib morphology ORPHA:2475
Fibrochondrogenesis
Hypoplastic scapulae, Narrow chest, Abnormal diaphysis morphology, Camptodactyly of finger, Broad... ORPHA:2021
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Abnormal clavicle morphology, Abnormal hip bone morphology, Abnormal rib morphology, Pectus excav... ORPHA:2522
Achondrogenesis Type 1B
Narrow chest, Short foot, Short thorax, Abnormal rib morphology ORPHA:93298
Melnick-Needles Syndrome
Short distal phalanx of finger, Hip dislocation, Narrow chest, Short thorax, Delayed cranial sutu... ORPHA:2484
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type
Thin ribs, Hypoplastic ilia, Metaphyseal cupping, Narrow chest, Thoracolumbar kyphosis, Radial bo... OMIM:151210
Lethal Congenital Contracture Syndrome Type 1
Abnormal hip bone morphology, Abnormality of the elbow, Slender long bone, Abnormal rib morphology ORPHA:1486
Craniosynostosis, Herrmann-Opitz Type
Finger syndactyly, Brachydactyly, Split hand, Abnormal rib morphology, Craniosynostosis ORPHA:2145
Mayer-Rokitansky-Küster-Hauser Syndrome Type 2
Abnormal rib morphology ORPHA:2578
Kenny-Caffey Syndrome, Type 1
Thin ribs, Small hand, Slender long bone, Delayed closure of the anterior fontanelle, Long clavic... OMIM:244460
Achondrogenesis, Type Ia
Broad clavicles, Hypoplastic scapulae, Narrow chest, Abnormal femoral metaphysis morphology, Bowi... OMIM:200600
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome
Radial bowing, Tibial bowing, Lower limb undergrowth, Bowing of the long bones, Abnormal fibula m... ORPHA:3035
Kyphomelic Dysplasia
Radial bowing, Flared metaphysis, Thoracic hypoplasia, Pterygium, Dumbbell-shaped humerus, Latera... OMIM:211350
Eiken Syndrome
Delayed epiphyseal ossification, Broad femoral neck, Clinodactyly, Long hallux, Broad ribs, Broad... OMIM:600002
Klippel-Feil Syndrome 1, Autosomal Dominant
Cervical C2/C3 vertebral fusion, Sprengel anomaly, Abnormal limb bone morphology, Abnormal rib mo... OMIM:118100
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly
Cone-shaped epiphysis, Metaphyseal spurs, Thoracic hypoplasia, Preaxial polydactyly, Acetabular s... OMIM:613091
Spondylometaphyseal Dysplasia, Sedaghatian Type
Delayed epiphyseal ossification, Widened greater sciatic notch, Horizontal inferior border of sca... OMIM:250220
Phaver Syndrome
Ulnar deviation of finger, Broad thumb, Short thumb, Camptodactyly of finger, Pterygium, Radiouln... ORPHA:2876
Ellis-Van Creveld Syndrome
Pectus carinatum, Capitate-hamate fusion, Postaxial foot polydactyly, Narrow chest, Hypoplastic i... OMIM:225500
Cooper-Jabs Syndrome
Camptodactyly of finger, Abnormal hip bone morphology, Missing ribs, Abnormal rib morphology, Pro... ORPHA:1488
Renpenning Syndrome
Abnormal thumb morphology, Sprengel anomaly, Abnormal rib morphology, Clinodactyly of the 5th fin... ORPHA:3242
Cenani-Lenz Syndrome
Synostosis of joints, Toe syndactyly, Synostosis of carpal bones, Finger syndactyly, Elbow disloc... ORPHA:3258
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome
Abnormal sternum morphology, Broad ribs, Short ribs, Abnormal rib morphology, Postaxial hand poly... ORPHA:2519
Antley-Bixler Syndrome
Narrow chest, Camptodactyly of finger, Delayed cranial suture closure, Femoral bowing, Arachnodac... ORPHA:83
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome
Abnormality of the humeroulnar joint, Abnormal rib morphology ORPHA:2234
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies
Sprengel anomaly, Abnormal rib morphology OMIM:601076
Imperforate Oropharynx-Costovertebral Anomalies Syndrome
Arachnodactyly, Clinodactyly of the 5th finger, Missing ribs, Abnormal rib morphology ORPHA:2759
Hydrocephalus-Costovertebral Dysplasia-Sprengel Anomaly Syndrome
Sandal gap, Sprengel anomaly, Brachydactyly, Abnormal rib morphology ORPHA:2180
Cleidocranial Dysplasia
Hypoplastic scapulae, Abnormal pelvic girdle bone morphology, Abnormal epiphysis morphology, Narr... ORPHA:1452
Mucopolysaccharidosis Type 4
Pectus carinatum, Abnormal epiphysis morphology, Joint dislocation, Short thorax, Genu valgum, Bo... ORPHA:582
Congenital Osteogenesis Imperfecta-Microcephaly-Cataracts Syndrome
Abnormal rib morphology ORPHA:2772
Short-Rib Thoracic Dysplasia 1 With Or Without Polydactyly
Narrow chest, Thoracic dysplasia, Irregular epiphyses, Hypoplastic iliac wing, Hypoplastic pelvis... OMIM:208500
Septopreoptic Holoprosencephaly
Abnormal rib morphology ORPHA:280195
Laryngotracheoesophageal Cleft Type 4
Abnormal rib morphology ORPHA:93941
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Short distal phalanx of finger, Short thumb, Preaxial hand polydactyly, Abnormal thumb morphology... ORPHA:1120
Spondylometaphyseal Dysplasia, Sedaghatian Type
Narrow chest, Cone-shaped epiphysis, Abnormal scapula morphology, Iliac crest serration, Metaphys... ORPHA:93317
Autosomal Recessive Spondylocostal Dysostosis
Finger syndactyly, Short thorax, Camptodactyly of finger, Rib segmentation abnormalities, Rib fus... ORPHA:2311
X-Linked Hypophosphatemia
Flattening of the talar dome, Shortening of the talar neck, Rachitic rosary, Abnormal epiphysis m... ORPHA:89936
Intellectual Disability-Myopathy-Short Stature-Endocrine Defect Syndrome
Clinodactyly of the 5th finger, Abnormal hip bone morphology, Pectus carinatum, Abnormal rib morp... ORPHA:3068
Oculocerebrocutaneous Syndrome
Short distal phalanx of finger, Congenital hip dislocation, Finger syndactyly, Missing ribs, Hand... ORPHA:1647
Cole-Carpenter Syndrome
Bowing of the long bones, Wormian bones, Abnormal rib morphology, Abnormal metaphysis morphology,... ORPHA:2050
Poland Syndrome
Small hand, Finger syndactyly, Aplasia/Hypoplasia of the sternum, Aplasia/Hypoplasia of the thumb... ORPHA:2911
Pyknoachondrogenesis
Short iliac bones, Horizontal ribs, Short ribs, Aplastic pubic bone, Short long bone, Short thora... ORPHA:3003
Campomelia, Cumming Type
Clubbing of toes, Abnormal thorax morphology, Bowing of the long bones, Brachydactyly, Abnormal r... ORPHA:1318
Holzgreve Syndrome
Hand polydactyly, Abnormal metacarpal morphology, Abnormal rib morphology, Abnormal morphology of... ORPHA:2167
Trisomy 13
Narrow chest, Abnormal pelvic girdle bone morphology, Ectrodactyly, Abnormal rib morphology, Post... ORPHA:3378
Prune Belly Syndrome
Congenital hip dislocation, Pectus excavatum, Abnormal rib morphology ORPHA:2970
Cartilage-Hair Hypoplasia
Pectus carinatum, Small hand, Abnormal pelvic girdle bone morphology, Abnormal epiphysis morpholo... ORPHA:175
Otopalatodigital Syndrome Type 2
Narrow chest, Synostosis of carpal bones, Elbow dislocation, Short thumb, Carpal synostosis, Prea... ORPHA:90652
Trisomy 1Q
Toe syndactyly, Short thorax, Camptodactyly of finger, Preaxial hand polydactyly, Arachnodactyly,... ORPHA:261344
Ulna And Fibula, Absence Of, With Severe Limb Deficiency
Radial bowing, Aplasia/Hypoplasia of the pubic bone, Fibular aplasia, Humeroradial synostosis, Ba... OMIM:276820
Axial Mesodermal Dysplasia Spectrum
Abnormality of the knee, Abnormal pelvic girdle bone morphology, Missing ribs, Abnormal rib morph... ORPHA:1834
Multiple Pterygium-Malignant Hyperthermia Syndrome
Ulnar deviation of finger, Finger syndactyly, Camptodactyly of finger, Arachnodactyly, Tapered fi... ORPHA:2215
Familial Osteodysplasia, Anderson Type
Aplastic clavicle, Bifid femur, Elbow dislocation, Abnormal rib morphology, Missing ribs, Aplasia... ORPHA:2769
Congenital Adrenal Hyperplasia Due To Cytochrome P450 Oxidoreductase Deficiency
Hypoplastic scapulae, Clinodactyly, Humeroradial synostosis, Arachnodactyly, Radioulnar synostosi... ORPHA:95699
Gorlin Syndrome
Arachnodactyly, Rib fusion, Brachydactyly, Anterior rib cupping, Abnormal rib morphology, Bifid r... ORPHA:377
Autosomal Dominant Popliteal Pterygium Syndrome
Popliteal pterygium, Toe syndactyly, Finger syndactyly, Split hand, Abnormal rib morphology ORPHA:1300
Tetraamelia-Multiple Malformations Syndrome
Missing ribs, Abnormal rib morphology, Aplasia/Hypoplasia involving the pelvis ORPHA:3301
Aspergillosis
Abnormal long bone morphology, Abnormal rib morphology ORPHA:1163
Radio-Renal Syndrome
Hypoplasia of the radius, Brachydactyly, Abnormal rib morphology, Short palm, Abnormality of the ... ORPHA:3015
Mosaic Trisomy 8
Narrow chest, Camptodactyly of finger, Patellar aplasia, Abnormal rib morphology, Narrow pelvis b... ORPHA:96061
Schwartz-Jampel Syndrome
Pectus carinatum, Shoulder flexion contracture, Elbow dislocation, Abnormal epiphysis morphology,... ORPHA:800
Fibrous Dysplasia Of Bone
Abnormal clavicle morphology, Abnormal rib morphology, Abnormal tibia morphology, Abnormal pelvis... ORPHA:249
Hurler Syndrome
Abnormal epiphysis morphology, Abnormal clavicle morphology, Abnormal diaphysis morphology, Campt... ORPHA:93473
Alagille Syndrome
Clinodactyly of the 5th finger, Short distal phalanx of finger, Hypoplasia of the ulna, Abnormal ... ORPHA:52
Vacterl/Vater Association
Aplasia/Hypoplasia of the radius, Finger syndactyly, Abnormal rib morphology, Preaxial hand polyd... ORPHA:887
Osteogenesis Imperfecta
Thin ribs, Abnormal tibia morphology, Genu valgum, Bowing of the long bones, Diaphyseal undertubu... ORPHA:666
Myhre Syndrome
Abnormal epiphysis morphology, Abnormal metaphysis morphology, Brachydactyly, Abnormal rib morpho... ORPHA:2588
Dextrocardia
Congenital hip dislocation, Abnormal rib morphology ORPHA:1666
Ear-Patella-Short Stature Syndrome
Aplastic clavicle, Abnormal epiphysis morphology, Slender long bone, Elbow dislocation, Camptodac... ORPHA:2554
Camptodactyly Syndrome, Guadalajara Type 3
Small hand, Broad femoral neck, Thickened cortex of long bones, Abnormal rib morphology, Short foot ORPHA:488434
Ulbright-Hodes Syndrome
Thin ribs, Abnormal forearm bone morphology, Fibular aplasia, Humeroradial synostosis, Short hume... ORPHA:3404
Monosomy 9Q22.3
Pectus excavatum, Metopic synostosis, Abnormal rib morphology, Polydactyly ORPHA:77301
Trisomy 18
Deviation of finger, Camptodactyly of finger, Abnormal hip bone morphology, Abnormal rib morpholo... ORPHA:3380
Hereditary Acrokeratotic Poikiloderma
Finger syndactyly, Camptodactyly of finger, Abnormal hip bone morphology, Abnormal metacarpal mor... ORPHA:2907
Simpson-Golabi-Behmel Syndrome
Congenital hip dislocation, Broad thumb, Toe syndactyly, Short toe, Finger syndactyly, Camptodact... ORPHA:373
Mucopolysaccharidosis Type 3
Abnormal clavicle morphology, Abnormal rib morphology, Avascular necrosis of the capital femoral ... ORPHA:581
Smith-Lemli-Opitz Syndrome
Ulnar deviation of finger, Aplasia/Hypoplasia of the radius, Postaxial foot polydactyly, Finger s... ORPHA:818
Autosomal Recessive Malignant Osteopetrosis
Narrow chest, Abnormal epiphysis morphology, Bowing of the long bones, Abnormal rib morphology, C... ORPHA:667
Vater/Vacterl Association
Short thumb, Abnormal rib morphology, Preaxial polydactyly, Abnormal sternum morphology, Radiouln... OMIM:192350
Kindler Epidermolysis Bullosa
Finger syndactyly, Camptodactyly of finger, Short 5th metacarpal, Short 4th metacarpal, Abnormal ... ORPHA:2908
Monosomy 9P
Abnormality of the tarsal bones, Proximal placement of thumb, Abnormal rib morphology, Postaxial ... ORPHA:261112
Oculocerebrorenal Syndrome Of Lowe
Abnormal epiphysis morphology, Abnormal rib morphology, Genu valgum, Joint swelling, Arthritis, P... ORPHA:534
Pagod Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:991
Charge Syndrome
Bifid femur, Abnormal tibia morphology, Polydactyly, Brachydactyly, Abnormal rib morphology, Clin... ORPHA:138
Alagille Syndrome 1
Short distal phalanx of finger, Hypoplasia of the ulna, Abnormal rib morphology OMIM:118450
Townes-Brocks Syndrome
Toe clinodactyly, Ulnar deviation of finger, Broad thumb, Toe syndactyly, Preaxial hand polydacty... ORPHA:857
Charge Syndrome
Bifid femur, Short thumb, Abnormal rib morphology, Down-sloping shoulders, Hand polydactyly, Radi... OMIM:214800
Fraser Syndrome
Toe syndactyly, Finger syndactyly, Wide pubic symphysis, Cutaneous syndactyly, Abnormal rib morph... ORPHA:2052

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxd8

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxd8.

No publications found that use IMPC mice or data for Hoxd8.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hoxd8tm459029(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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