banner
Genes Phenotypes Help, News, Blog

Gene: Hoxa6 MGI:96178

Log in to follow
Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
homeobox A6
Synonyms:
Hox-1.2

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hoxa6 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Hoxa6 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Cervical Rib
Cervical ribs OMIM:117900
Neurogenic Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:100073
Spondylocostal Dysostosis 2, Autosomal Recessive
Vertebral segmentation defect, Rib fusion, Short neck, Vertebral clefting, Hemivertebrae OMIM:608681
Spondylocostal Dysostosis 3, Autosomal Recessive
Hypoplasia of the odontoid process, Contracture of the proximal interphalangeal joint of the 2nd ... OMIM:609813
Sprengel Deformity
Rib segmentation abnormalities, Sprengel anomaly, Hemivertebrae, Spina bifida occulta, Cervical s... OMIM:184400
Radioulnar Synostosis-Microcephaly-Scoliosis Syndrome
Pectus carinatum, Radioulnar synostosis, Abnormal rib morphology, Scoliosis, Abnormality of the e... ORPHA:3268
Spondylocostal Dysostosis 5
Pectus carinatum, Butterfly vertebrae, Missing ribs, Supernumerary ribs, Short neck, Low back pai... OMIM:122600
Hypo- And Hypermelanotic Cutaneous Macules-Retarded Growth-Intellectual Disability Syndrome
Abnormal rib morphology ORPHA:2435
Klippel-Feil Syndrome 3, Autosomal Dominant
Cervical C5/C6 vertebrae fusion, Cervical C3/C4 vertebral fusion, Thoracic scoliosis OMIM:613702
Thoracic Dysostosis, Isolated
Pectus excavatum, Bell-shaped thorax, Short ribs OMIM:187750
Thoracomelic Dysplasia
Bell-shaped thorax, Short ribs OMIM:273740
Hypogonadism, Male, With Impaired Intellectual Development And Skeletal Anomalies
Abnormality of the cervical spine, Superior rib anomalies OMIM:307500
Short-Rib Thoracic Dysplasia 17 With Or Without Polydactyly
Narrow chest, Acetabular spurs, Horizontal ribs, Short ribs, Trident acetabulum, Lateral clavicle... OMIM:617405
Heart Defects-Limb Shortening Syndrome
Narrow chest, Kyphosis, Abnormal form of the vertebral bodies, Abnormal rib morphology ORPHA:1354
Becker Nevus Syndrome
Pectus excavatum, Scoliosis, Hemivertebrae, Cervical ribs OMIM:604919
Endosteal Hyperostosis, Worth Type
Sclerotic vertebral body, Abnormal form of the vertebral bodies, Clavicular sclerosis, Abnormal r... ORPHA:2790
Kyphomelic Dysplasia
Narrow chest, Abnormal form of the vertebral bodies, Undulate ribs, Missing ribs, Anterior rib cu... ORPHA:1801
Spondylocostal Dysostosis 1, Autosomal Recessive
Block vertebrae, Abnormal odontoid process morphology, Kyphoscoliosis, Rib fusion, Vertebral segm... OMIM:277300
Autosomal Dominant Spondylocostal Dysostosis
Abnormal sacrum morphology, Abnormal rib morphology, Vertebral segmentation defect, Missing ribs,... ORPHA:1797
Spondylometaphyseal Dysplasia, A4 Type
Platyspondyly, Flared, irregular rib ends ORPHA:168555
Thoracolaryngopelvic Dysplasia
Bell-shaped thorax, Horizontal ribs, Short ribs, Irregular chondrocostal junctions, Scoliosis, Ir... OMIM:187760
Osteogenesis Imperfecta, Type Ix
Platyspondyly, Pectus carinatum, Multiple rib fractures, Wormian bones, Pectus excavatum, Scolios... OMIM:259440
Isolated Klippel-Feil Syndrome
Abnormality of the vertebral column, Abnormal shoulder morphology, Cervical C2/C3 vertebral fusio... ORPHA:2345
Diaphanospondylodysostosis
Absent or minimally ossified vertebral bodies, Missing ribs, Abnormal vertebral segmentation and ... ORPHA:66637
Mesomelic Dysplasia, Kantaputra Type
Abnormality of the ankle, Synostosis of carpal bones, Camptodactyly of finger, Vertebral segmenta... ORPHA:1836
Metatropic Dysplasia
Narrow chest, Hypoplastic cervical vertebrae, Abnormal form of the vertebral bodies, Camptodactyl... ORPHA:2635
Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3
Thin ribs, Platyspondyly, Multiple joint dislocation, Knee dislocation, Narrow vertebral interped... OMIM:618395
Hypersulfaturia
Costochondral pain OMIM:620372
Mayer-Rokitansky-Küster-Hauser Syndrome Type 2
Vertebral segmentation defect, Short neck, Abnormal rib morphology ORPHA:2578
Klippel-Feil Syndrome 2, Autosomal Recessive
Cervical C2/C3 vertebral fusion, Short neck, Sprengel anomaly, Scoliosis, Fused cervical vertebrae OMIM:214300
Congenital Pseudoarthrosis Of The Clavicle
Congenital pseudoarthrosis of the clavicle, Osteoarthritis, Cervical ribs ORPHA:66630
X-Linked Skeletal Dysplasia-Intellectual Disability Syndrome
Thoracic hemivertebrae, Abnormal sacrum morphology, Scoliosis, Fused cervical vertebrae ORPHA:1436
Male Hypergonadotropic Hypogonadism-Intellectual Disability-Skeletal Anomalies Syndrome
Abnormal form of the vertebral bodies, Abnormality of the humeroulnar joint, Short neck, Hemivert... ORPHA:2234
Short-Rib Thoracic Dysplasia 11 With Or Without Polydactyly
Narrow chest, Thoracic dysplasia, Bell-shaped thorax, Horizontal ribs, Lateral clavicle hook OMIM:615633
Spondyloepimetaphyseal Dysplasia, Irapa Type
Platyspondyly, Pectus carinatum, Hypoplastic sacrum, Lumbar hyperlordosis, Genu valgum, Limited e... OMIM:271650
Craniodiaphyseal Dysplasia
Abnormal rib morphology ORPHA:1513
Pierre Robin Sequence With Pectus Excavatum And Rib And Scapular Anomalies
Pectus excavatum, Hypoplastic distal segments of scapulae, Abnormal rib morphology OMIM:602196
Poland Syndrome
Rib fusion, Sprengel anomaly, Hemivertebrae, Short ribs OMIM:173800
Microcephaly-Cervical Spine Fusion Anomalies Syndrome
Abnormal clavicle morphology, Short neck, Hyperlordosis, Abnormal rib morphology, Pectus excavatu... ORPHA:2522
Metatropic Dysplasia
Platyspondyly, Anisospondyly, Narrow chest, Hypoplasia of the odontoid process, Caudal appendage,... OMIM:156530
Osteogenesis Imperfecta, Type Xv
Thin ribs, Platyspondyly, Scoliosis OMIM:615220
Spondylocostal Dysostosis 4, Autosomal Recessive
Block vertebrae, Abnormal odontoid process morphology, Bell-shaped thorax, Vertebral segmentation... OMIM:613686
Becker Nevus Syndrome
Pectus carinatum, Rib fusion, Supernumerary ribs, Spina bifida occulta, Pectus excavatum, Scolios... ORPHA:64755
Fibrochondrogenesis 2
Platyspondyly, Thoracic hypoplasia, Bell-shaped thorax, Short ribs, Cupped ribs OMIM:614524
Spondyloepimetaphyseal Dysplasia, Irapa Type
Platyspondyly, Pectus carinatum, Synostosis of carpal bones, Abnormal joint morphology, Genu valg... ORPHA:93351
Thoracic Outlet Syndrome
Abnormal rib morphology ORPHA:97330
Christian Syndrome
Thoracic hemivertebrae, Scoliosis, Fused cervical vertebrae, Prominent metopic ridge OMIM:309620
Spondylomegaepiphyseal Dysplasia With Upper Limb Mesomelia, Punctate Calcifications, And Deafness
Platyspondyly, Lumbar hyperlordosis, Cupped ribs, Beaking of vertebral bodies, Flat acetabular ro... OMIM:609616
Thin Ribs-Tubular Bones-Dysmorphism Syndrome
Abnormal rib morphology ORPHA:1506
Axial Spondylometaphyseal Dysplasia
Platyspondyly, Narrow chest, Posterior wedging of vertebral bodies, Thoracic hypoplasia, Aplasia/... ORPHA:168549
Klippel-Feil Syndrome 1, Autosomal Dominant
Cervical C2/C3 vertebral fusion, Short neck, Sprengel anomaly, Abnormal rib morphology, Scoliosis... OMIM:118100
Contractures, Pterygia, And Spondylocarpotarsal Fusion Syndrome 1B
Short neck, Fused thoracic vertebrae, Antecubital pterygium, Tarsal synostosis, Scoliosis, Fused ... OMIM:618469
Cloverleaf Skull-Multiple Congenital Anomalies Syndrome
Platyspondyly, Narrow chest, Abnormal clavicle morphology, Short neck, Abnormal rib morphology ORPHA:93267
Grant Syndrome
Abnormality of the glenoid fossa, Narrow chest, Joint dislocation, Wormian bones, Sprengel anomal... ORPHA:2097
Mosaic Trisomy 14
Short neck, Narrow chest, Abnormal rib morphology, Camptodactyly of finger ORPHA:1703
Autosomal Recessive Spondylocostal Dysostosis
Abnormal form of the vertebral bodies, Abnormal rib morphology, Camptodactyly of finger, Rib segm... ORPHA:2311
Lethal Congenital Contracture Syndrome Type 1
Short neck, Abnormality of the elbow, Abnormal form of the vertebral bodies, Abnormal rib morphology ORPHA:1486
Mucopolysaccharidosis, Type X
Platyspondyly, Broad clavicles, Irregular acetabular roof, Broad ribs, Genu valgum, Spatulate rib... OMIM:619698
Jeune Syndrome
Narrow chest, Abnormal clavicle morphology, Abnormal sternum morphology, Abnormal rib morphology,... ORPHA:474
Laryngotracheoesophageal Cleft Type 4
Abnormal form of the vertebral bodies, Abnormal rib morphology ORPHA:93941
10Q22.3Q23.3 Microduplication Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:276422
Mucopolysaccharidosis, Type Iva
Platyspondyly, Pectus carinatum, Hypoplasia of the odontoid process, Kyphosis, Ulnar deviation of... OMIM:253000
Juberg-Hayward Syndrome
Abnormal vertebral morphology, Abnormality of the wrist, Radioulnar synostosis, Abnormal rib morp... ORPHA:2319
Dyggve-Melchior-Clausen Disease
Platyspondyly, Pectus carinatum, Hypoplastic acetabulae, Abnormality of the ankle, Hypoplasia of ... ORPHA:239
Hydrocephalus-Costovertebral Dysplasia-Sprengel Anomaly Syndrome
Abnormal form of the vertebral bodies, Sprengel anomaly, Hemivertebrae, Abnormal rib morphology, ... ORPHA:2180
Schneckenbecken Dysplasia
Platyspondyly, Hypoplastic scapulae, Narrow chest, Thoracic hypoplasia, Short ribs, Narrow verteb... OMIM:269250
Septopreoptic Holoprosencephaly
Abnormal vertebral morphology, Abnormal rib morphology ORPHA:280195
Diastrophic Dysplasia
Abnormal clavicle morphology, Joint dislocation, Elbow dislocation, Camptodactyly of finger, Hypo... ORPHA:628
Achondrogenesis Type 1B
Short neck, Narrow chest, Short thorax, Abnormal rib morphology ORPHA:93298
Mucopolysaccharidosis Type 4
Platyspondyly, Pectus carinatum, Joint dislocation, Abnormal rib morphology, Spinal canal stenosi... ORPHA:582
White Forelock With Malformations
Spina bifida occulta, Sprengel anomaly, Abnormal rib morphology ORPHA:2475
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies
Sprengel anomaly, Abnormality of the vertebral column, Abnormal rib morphology OMIM:601076
Fibrochondrogenesis
Hypoplastic scapulae, Narrow chest, Abnormal form of the vertebral bodies, Camptodactyly of finge... ORPHA:2021
Femoral-Facial Syndrome
Vertebral segmentation defect, Rib fusion, Radioulnar synostosis, Sprengel anomaly, Abnormal rib ... ORPHA:1988
Holt-Oram Syndrome
Abnormal clavicle morphology, Down-sloping shoulders, Radioulnar synostosis, Sprengel anomaly, Ab... ORPHA:392
Imperforate Oropharynx-Costovertebral Anomalies Syndrome
Missing ribs, Abnormal form of the vertebral bodies, Hemivertebrae, Abnormal rib morphology ORPHA:2759
Osteogenesis Imperfecta, Type Ii
Thin ribs, Platyspondyly, Thoracic hypoplasia, Bell-shaped thorax, Multiple rib fractures, Wormia... OMIM:166210
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Thin ribs, Block vertebrae, Supernumerary vertebrae, Short ribs, Missing ribs, Rib fusion, Short ... OMIM:271520
Platyspondylic Lethal Skeletal Dysplasia, Torrance Type
Thin ribs, Thoracolumbar kyphosis, Narrow chest, Thoracic hypoplasia, Disc-like vertebral bodies,... OMIM:151210
Cat-Eye Syndrome
Abnormal rib morphology ORPHA:195
3M Syndrome
Thin ribs, Congenital hip dislocation, Enlarged thorax, Increased vertebral height, Horizontal ri... ORPHA:2616
Osteogenesis Imperfecta, Type Xviii
Thin ribs, Wormian bones, Vertebral compression fracture, Biconcave vertebral bodies OMIM:617952
Microcephalic Primordial Dwarfism, Toriello Type
Abnormal rib morphology ORPHA:2643
Phaver Syndrome
Abnormal form of the vertebral bodies, Camptodactyly of finger, Pterygium, Butterfly vertebrae, R... ORPHA:2876
Cole-Carpenter Syndrome
Abnormal form of the vertebral bodies, Wormian bones, Abnormal rib morphology, Scoliosis, Kyphosis ORPHA:2050
Hypophosphatasia
Craniosynostosis, Narrow chest, Abnormal rib morphology ORPHA:436
Cole-Carpenter Syndrome 2
Thin ribs, Lambdoidal craniosynostosis, Coronal craniosynostosis, Platyspondyly, Wide cranial sut... OMIM:616294
Melnick-Needles Syndrome
Anisospondyly, Narrow chest, Abnormal rib morphology, Delayed cranial suture closure, Short clavi... ORPHA:2484
Osteogenesis Imperfecta, Type Iii
Thin ribs, Biconcave vertebral bodies, Wormian bones, Scoliosis, Kyphosis, Protrusio acetabuli OMIM:259420
Cooper-Jabs Syndrome
Missing ribs, Scoliosis, Abnormal rib morphology, Camptodactyly of finger ORPHA:1488
Achondrogenesis, Type Ia
Broad clavicles, Hypoplastic scapulae, Narrow chest, Unossified vertebral bodies, Hypoplastic sac... OMIM:200600
Fibrochondrogenesis 1
Thin ribs, Platyspondyly, Joint contracture of the hand, Hypoplastic scapulae, Thoracic hypoplasi... OMIM:228520
Intellectual Disability-Polydactyly-Uncombable Hair Syndrome
Pectus carinatum, Short neck, Kyphosis, Abnormal rib morphology ORPHA:3082
Cerebrofaciothoracic Dysplasia
Narrow chest, Vertebral segmentation defect, Rib fusion, Short neck, Sprengel anomaly, Bifid ribs... ORPHA:1394
Acro-Renal-Mandibular Syndrome
Thin ribs, Pectus carinatum, Hypoplastic scapulae, Abnormal clavicle morphology, Kyphosis, Butter... ORPHA:958
Prune Belly Syndrome
Congenital hip dislocation, Vertebral segmentation defect, Abnormal rib morphology, Pectus excava... ORPHA:2970
Axial Mesodermal Dysplasia Spectrum
Abnormal form of the vertebral bodies, Vertebral segmentation defect, Missing ribs, Short neck, A... ORPHA:1834
Osteogenesis Imperfecta, Type Xvi
Platyspondyly, Narrow chest, Multiple rib fractures, Wormian bones, Vertebral compression fracture OMIM:616229
Growth Delay-Hydrocephaly-Lung Hypoplasia Syndrome
Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:3035
Mucolipidosis Iii Alpha/Beta
Shallow acetabular fossae, Broad ribs, Irregular carpal bones, Spondylolisthesis, Short ribs, Car... OMIM:252600
Congenital Osteogenesis Imperfecta-Microcephaly-Cataracts Syndrome
Abnormal rib morphology ORPHA:2772
Osteogenesis Imperfecta, Type X
Thin ribs, Platyspondyly, Narrow chest, Thoracic hypoplasia, Broad ribs, Genu valgum, Thoracic sc... OMIM:613848
Cenani-Lenz Syndrome
Synostosis of joints, Synostosis of carpal bones, Elbow dislocation, Abnormal form of the vertebr... ORPHA:3258
Metaphyseal Dysostosis, Impaired Intellectual Development, And Conductive Deafness
Flat glenoid fossa, Lumbar hyperlordosis, Genu valgum, Short ribs, Carpal bone hypoplasia, Cupped... OMIM:250420
Craniosynostosis, Herrmann-Opitz Type
Craniosynostosis, Abnormal rib morphology ORPHA:2145
Microcephaly-Seizures-Intellectual Disability-Heart Disease Syndrome
Broad ribs, Abnormal sternum morphology, Abnormal rib morphology, Short ribs ORPHA:2519
Gorlin Syndrome
Abnormal vertebral morphology, Vertebral wedging, Abnormal rib morphology, Rib fusion, Bifid ribs... ORPHA:377
Renpenning Syndrome
Pectus excavatum, Sprengel anomaly, Abnormal rib morphology ORPHA:3242
Intellectual Disability-Myopathy-Short Stature-Endocrine Defect Syndrome
Pectus carinatum, Hyperlordosis, Abnormal rib morphology ORPHA:3068
Chronic Recurrent Multifocal Osteomyelitis 2, With Periostitis And Pustulosis
Broad ribs, Flaring of rib cage, Joint swelling, Fused cervical vertebrae OMIM:612852
Rhizomelic Skeletal Dysplasia With Or Without Pelger-Huet Anomaly
Thoracolumbar kyphosis, Platyspondyly, Joint dislocation, Thoracic hypoplasia, Thoracic platyspon... OMIM:618019
Holzgreve Syndrome
Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:2167
Familial Osteodysplasia, Anderson Type
Aplastic clavicle, Abnormal form of the vertebral bodies, Elbow dislocation, Missing ribs, Abnorm... ORPHA:2769
Antley-Bixler Syndrome
Narrow chest, Camptodactyly of finger, Delayed cranial suture closure, Elbow ankylosis, Abnormal ... ORPHA:83
Campomelia, Cumming Type
Abnormal thorax morphology, Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:1318
Bent Bone Dysplasia Syndrome 2
Thin ribs, Platyspondyly, Hypoplastic acetabulae, Butterfly vertebrae, Short ribs, Short sternum,... OMIM:620076
Osteogenesis Imperfecta, Type Viii
Thin ribs, Platyspondyly, Barrel-shaped chest, Wormian bones, Vertebral compression fracture, Sco... OMIM:610915
Lung Agenesis-Heart Defect-Thumb Anomalies Syndrome
Vertebral segmentation defect, Abnormal rib morphology ORPHA:1120
Cleidocranial Dysplasia
Hypoplastic scapulae, Narrow chest, Genu valgum, Down-sloping shoulders, Short clavicles, Wormian... ORPHA:1452
Trisomy 13
Narrow chest, Scoliosis, Kyphosis, Abnormal rib morphology ORPHA:3378
Radio-Renal Syndrome
Short neck, Abnormal form of the vertebral bodies, Abnormal rib morphology, Abnormality of the elbow ORPHA:3015
Poland Syndrome
Asymmetry of the thorax, Pectus carinatum, Abnormal sternum morphology, Aplasia/Hypoplasia of the... ORPHA:2911
Mosaic Trisomy 8
Narrow chest, Camptodactyly of finger, Patellar aplasia, Vertebral segmentation defect, Short nec... ORPHA:96061
Alagille Syndrome
Abnormal form of the vertebral bodies, Vertebral segmentation defect, Butterfly vertebral arch, A... ORPHA:52
Kyphomelic Dysplasia
Platyspondyly, Thoracic hypoplasia, Pterygium, Undulate ribs, Anterior rib cupping, Flat acetabul... OMIM:211350
Pyknoachondrogenesis
Unossified sacrum, Horizontal ribs, Short ribs, Poorly ossified vertebrae, Short thorax, Enlarged... ORPHA:3003
Tetraamelia-Multiple Malformations Syndrome
Missing ribs, Abnormally ossified vertebrae, Abnormal rib morphology ORPHA:3301
Spondylometaphyseal Dysplasia, Sedaghatian Type
Platyspondyly, Narrow chest, Abnormal scapula morphology, Abnormal rib morphology ORPHA:93317
Cartilage-Hair Hypoplasia
Pectus carinatum, Narrow chest, Biconvex vertebral bodies, Abnormal form of the vertebral bodies,... ORPHA:175
Hurler Syndrome
Abnormal vertebral morphology, Abnormal clavicle morphology, Camptodactyly of finger, Spinal cana... ORPHA:93473
Aspergillosis
Abnormality of the vertebral column, Abnormal rib morphology ORPHA:1163
Oculocerebrocutaneous Syndrome
Missing ribs, Congenital hip dislocation, Abnormal rib morphology ORPHA:1647
Multiple Pterygium-Malignant Hyperthermia Syndrome
Camptodactyly of finger, Abnormal rib morphology, Pectus excavatum, Scoliosis, Kyphosis, Prominen... ORPHA:2215
Autosomal Dominant Popliteal Pterygium Syndrome
Popliteal pterygium, Scoliosis, Abnormal rib morphology ORPHA:1300
Vacterl/Vater Association
Vertebral segmentation defect, Abnormal sacrum morphology, Abnormal intervertebral disk morpholog... ORPHA:887
Schwartz-Jampel Syndrome
Platyspondyly, Pectus carinatum, Shoulder flexion contracture, Elbow dislocation, Abnormally ossi... ORPHA:800
Osteogenesis Imperfecta, Type Vii
Narrow chest, Delayed cranial suture closure, Multiple rib fractures, Wormian bones, Wide cranial... OMIM:610682
Otopalatodigital Syndrome Type 2
Narrow chest, Synostosis of carpal bones, Elbow dislocation, Camptodactyly of finger, Carpal syno... ORPHA:90652
Trisomy 1Q
Short thorax, Abnormal rib morphology, Camptodactyly of finger ORPHA:261344
Monosomy 9Q22.3
Abnormality of the vertebral column, Abnormal rib morphology, Short neck, Metopic synostosis, Pec... ORPHA:77301
Congenital Adrenal Hyperplasia Due To Cytochrome P450 Oxidoreductase Deficiency
Abnormal vertebral morphology, Hypoplastic scapulae, Narrow chest, Elbow flexion contracture, Abn... ORPHA:95699
Osteogenesis Imperfecta
Thin ribs, Pectus carinatum, Narrow chest, Cervical kyphosis, Thoracic hypoplasia, Abnormal form ... ORPHA:666
Dextrocardia
Congenital hip dislocation, Abnormal rib morphology ORPHA:1666
Camptodactyly Syndrome, Guadalajara Type 3
Spina bifida occulta, Short neck, Abnormal rib morphology ORPHA:488434
Fibrous Dysplasia Of Bone
Abnormal clavicle morphology, Abnormal lumbar spine morphology, Abnormality of the cervical spine... ORPHA:249
Mucopolysaccharidosis Type 3
Abnormal clavicle morphology, Abnormal form of the vertebral bodies, Genu valgum, Abnormal rib mo... ORPHA:581
Myhre Syndrome
Platyspondyly, Abnormal rib morphology ORPHA:2588
Simpson-Golabi-Behmel Syndrome
Congenital hip dislocation, Camptodactyly of finger, Vertebral segmentation defect, Short neck, A... ORPHA:373
Ear-Patella-Short Stature Syndrome
Aplastic clavicle, Elbow dislocation, Camptodactyly of finger, Patellar aplasia, Abnormal rib mor... ORPHA:2554
Monosomy 9P
Short neck, Scoliosis, Abnormality of the vertebral column, Abnormal rib morphology ORPHA:261112
Ulbright-Hodes Syndrome
Thin ribs, Humeroradial synostosis, Short ribs, Short sternum, Short neck, Ovoid thoracolumbar ve... ORPHA:3404
Vater/Vacterl Association
Abnormal vertebral morphology, Abnormal sternum morphology, Radioulnar synostosis, Abnormal rib m... OMIM:192350
Smith-Lemli-Opitz Syndrome
Hip dislocation, Abnormal form of the vertebral bodies, Short neck, Abnormal rib morphology, Scol... ORPHA:818
Trisomy 18
Abnormal rib morphology, Camptodactyly of finger ORPHA:3380
Oculocerebrorenal Syndrome Of Lowe
Platyspondyly, Kyphosis, Abnormal rib morphology, Genu valgum, Joint swelling, Arthritis, Patella... ORPHA:534
Hereditary Acrokeratotic Poikiloderma
Abnormal rib morphology, Camptodactyly of finger ORPHA:2907
Pagod Syndrome
Abnormal clavicle morphology, Abnormal rib morphology ORPHA:991
Alagille Syndrome 1
Butterfly vertebral arch, Hemivertebrae, Abnormal rib morphology OMIM:118450
Autosomal Recessive Malignant Osteopetrosis
Craniosynostosis, Narrow chest, Abnormal rib morphology ORPHA:667
Kindler Epidermolysis Bullosa
Abnormal rib morphology, Camptodactyly of finger ORPHA:2908
Charge Syndrome
Scoliosis, Hemivertebrae, Abnormal rib morphology ORPHA:138
Fraser Syndrome
Vertebral segmentation defect, Abnormal rib morphology ORPHA:2052
Charge Syndrome
Down-sloping shoulders, Radial head subluxation, Hemivertebrae, Abnormal rib morphology, Scoliosis OMIM:214800
Townes-Brocks Syndrome
Abnormal vertebral morphology, Abnormal rib morphology ORPHA:857

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hoxa6

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hoxa6.

No publications found that use IMPC mice or data for Hoxa6.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Hoxa6tm87145(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Hoxa6tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter