Gene: Hexb

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Phenotype System Allele Zyg Sex Life Stage P Value
increased monocyte cell number Hexbtm1b(EUCOMM)Hmgu HOM Early adult 5.47×10-07
decreased circulating fructosamine level Hexbtm1b(EUCOMM)Hmgu HOM Early adult 1.20×10-07
increased circulating aspartate transaminase level Hexbtm1b(EUCOMM)Hmgu HOM Early adult 8.02×10-10
thrombocytosis Hexbtm1b(EUCOMM)Hmgu HOM Early adult 6.11×10-05
tremors Hexbtm1b(EUCOMM)Hmgu HOM Early adult 6.49×10-06
increased circulating alkaline phosphatase level Hexbtm1b(EUCOMM)Hmgu HOM Early adult 9.76×10-21
abnormal gait Hexbtm1b(EUCOMM)Hmgu HOM Early adult 4.65×10-11
decreased circulating creatinine level Hexbtm1b(EUCOMM)Hmgu HOM Early adult 2.01×10-06
increased circulating creatinine level Hexbtm1b(EUCOMM)Hmgu HOM Early adult 2.01×10-06
abnormal locomotor behavior Hexbtm1b(EUCOMM)Hmgu HOM Early adult 2.34×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
12 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hexbtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Hexbtm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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