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Genes Phenotypes

Gene: Hc

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Name
hemolytic complement
MGI ID
MGI:96031
Synonyms
C5a C5 He Hfib2
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (184) All data table (438)
Expression & images (73) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased lean body mass Hctm1b(EUCOMM)Wtsi HOM Early adult 5.02×10-05
decreased urine creatinine level Hctm1b(EUCOMM)Wtsi HOM Early adult 3.22×10-08
decreased grip strength Hctm1b(EUCOMM)Wtsi HOM Early adult 6.56×10-05
abnormal bone structure Hctm1b(EUCOMM)Wtsi HOM Early adult 2.08×10-05
abnormal sleep behavior Hctm1b(EUCOMM)Wtsi HOM Early adult 2.87×10-11

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590) N/A
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (1/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (1/2)  Section images
Spleen 2 No  (2/590)  (2/2)  Section images
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (5/590) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (1/2)  Section images
Trachea 2 No  (2/590)  (2/2)  Section images
Urinary bladder 2 No N/A
Uterus 2 No  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
digestive system (3)
Liver no expression
MA:0000358
endocrine system (1)
Thyroid gland expression
MA:0000129
exocrine system (1)
Submandibular Gland expression
MA:0001589
immune system (1)
Spleen expression
MA:0000141
nervous system (1)
Spinal cord expression
MA:0000216
postnatal mouse (12)
Kidney expression
MA:0000368
reproductive system (2)
Ovary expression
MA:0000384
respiratory system (4)
Lung no expression
MA:0000415
trunk (10)
Kidney expression
MA:0000368
urinary system (1)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506) N/A
Dorsal root ganglion 2  (1/61) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507) N/A
Eye 2  (1/506) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Fronto-nasal process 2  (1/62) N/A
Hand 2  (1/506) N/A
Head 2  (5/506) N/A
Heart 2  (1/506) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Nose 2  (1/76) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Spinal cord 2  (1/73) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

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Original Image
Adult LacZ: LacZ Images Section
12 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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Eye Morphology: Images Ophthalmoscopy
10 Images
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X-ray: XRay Images Skull Lateral Orientation
10 Images
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Sleep Wake: Wake state (bmp file)
3 Images
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X-ray: XRay Images Forepaw
10 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Electroretinography 2: Rod and cone PDF
4 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Hctm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Hctm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Hctm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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