Gene Summary

Name:
glutamate receptor, ionotropic, kainate 4
Synonyms:
KA1,  GluRgamma1,  KA-1,  6330551K01Rik

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal eye morphology Grik4em1(IMPC)Mbp HOM Early adult 0.00
decreased lean body mass Grik4em1(IMPC)Mbp HOM Early adult 4.31×10-05
increased total body fat amount Grik4em1(IMPC)Mbp HOM Early adult 4.28×10-05
impaired glucose tolerance Grik4em1(IMPC)Mbp HOM Early adult 2.32×10-05
decreased prepulse inhibition Grik4em1(IMPC)Mbp HOM   Early adult 2.81×10-07

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

66 Images

X-ray

XRay Images Whole Body Lateral Orientation

22 Images

Human diseases caused by Grik4 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Grik4 by phenotypic similarity.

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Grik4

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Grik4.

No publications found that use IMPC mice or data for Grik4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Grik4em1(IMPC)Mbp Exon Deletion Mice, Tissue
Grik4tm44502(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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