Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases associated to Grik2 by orthology or direct annotation.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Neurodevelopmental Disorder With Impaired Language And Ataxia And With Or Without Seizures | Myoclonic seizure, Epileptic spasm, Short attention span, Emotional lability, Recurrent hand flap... | OMIM:619580 | |
Intellectual Developmental Disorder, Autosomal Recessive 6 | Myoclonus, Atonic seizure | OMIM:611092 |
The table below shows human diseases predicted to be associated to Grik2 by phenotypic similarity.
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MGI Allele | Allele Type | Produced |
---|---|---|
Grik2tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | ES Cells |
Grik2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
Grik2tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | Targeting vectors, ES Cells |
Grik2tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | Mice |
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