Gene: Grb2

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Name
growth factor receptor bound protein 2
MGI ID
MGI:95805
Synonyms
N/A
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Grb2tm1a(EUCOMM)Wtsi HET Early adult 3.31×10-05
hyperactivity Grb2tm1a(EUCOMM)Wtsi HET Early adult 2.78×10-05
decreased circulating serum albumin level Grb2tm1a(EUCOMM)Wtsi HET   Early adult 1.79×10-05
thrombocytosis Grb2tm1a(EUCOMM)Wtsi HET Early adult 1.35×10-05
preweaning lethality, complete penetrance Grb2tm1a(EUCOMM)Wtsi HOM   Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584)  (2/2) N/A
Aorta 2 No  (1/584) N/A
Blood vessel 2 No  (1/2) N/A
Bone 2 No N/A
Brain 2 No  (4/584)  (2/2) N/A
Brainstem 2 No  (2/584) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/584)  (2/2) N/A
Cerebellum 2 No  (3/584) N/A
Cerebral cortex 2 No  (2/584) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/584)  (2/2) N/A
Hippocampus 2 No  (3/584) N/A
Hypothalamus 2 No  (2/584) N/A
Kidney 2 No  (21/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (1/584)  (2/2) N/A
Lung 2 No  (2/584)  (2/2) N/A
Lymph node 2 No  (1/584)  (2/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/584) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Parathyroid gland 2 No  (1/562)  (2/2) N/A
Peripheral nervous system 2 No  (2/584)  (2/2) N/A
Peyer's patch 2 No  (1/176)  (2/2) N/A
Pituitary gland 2 No  (1/584)  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (1/584)  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (3/584)  (2/2) N/A
Spleen 2 No  (3/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (3/584) N/A
Testis 2 No  (6/584)  (1/2) N/A
Thymus 2 No  (1/584)  (2/2) N/A
Thyroid gland 2 No  (16/584)  (2/2) N/A
Trachea 2 No  (3/584)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Section Images

View all 26 images

View all 16 images

No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images

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 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Grb2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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