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Gene: Grb2

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Name
growth factor receptor bound protein 2
MGI ID
MGI:95805
Synonyms
N/A
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (5) Measurements chart (147) All data table (294)
Expression & images (45) Disease models (0) Order (1)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Grb2tm1a(EUCOMM)Wtsi HET Early adult 3.31×10-05
hyperactivity Grb2tm1a(EUCOMM)Wtsi HET Early adult 2.78×10-05
decreased circulating serum albumin level Grb2tm1a(EUCOMM)Wtsi HET   Early adult 1.79×10-05
thrombocytosis Grb2tm1a(EUCOMM)Wtsi HET Early adult 1.35×10-05
preweaning lethality, complete penetrance Grb2tm1a(EUCOMM)Wtsi HOM   Early adult 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584)  (2/2) N/A
Aorta 2 No  (1/584) N/A
Blood vessel 2 No  (1/2) N/A
Bone 2 No N/A
Brain 2 No  (4/584)  (2/2) N/A
Brainstem 2 No  (2/584) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/584)  (2/2) N/A
Cerebellum 2 No  (3/584) N/A
Cerebral cortex 2 No  (2/584) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/584)  (2/2) N/A
Hippocampus 2 No  (3/584) N/A
Hypothalamus 2 No  (2/584) N/A
Kidney 2 No  (21/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No  (1/584)  (2/2) N/A
Lung 2 No  (2/584)  (2/2) N/A
Lymph node 2 No  (1/584)  (2/2) N/A
Mammary gland 2 No N/A
Esophagus 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/584) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Parathyroid gland 2 No  (1/562)  (2/2) N/A
Peripheral nervous system 2 No  (2/584)  (2/2) N/A
Peyer's patch 2 No  (1/176)  (2/2) N/A
Pituitary gland 2 No  (1/584)  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 2 No  (1/584)  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (3/584)  (2/2) N/A
Spleen 2 No  (3/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (3/584) N/A
Testis 2 No  (6/584)  (1/2) N/A
Thymus 2 No  (1/584)  (2/2) N/A
Thyroid gland 2 No  (16/584)  (2/2) N/A
Trachea 2 No  (3/584)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Grb2tm1a(EUCOMM)Wtsi
eye, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
skin, pinna, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
lower urinary tract, urinary bladder, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI

View all 26 images

Grb2tm1a(EUCOMM)Wtsi
lower urinary tract, urinary bladder, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
gall bladder, liver, HET, Female, WTSI

View all 16 images

Grb2tm1a(EUCOMM)Wtsi
gall bladder, liver, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
oesophagus, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
large intestine, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
thymus, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
lymph node, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
spleen, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
peyer's patch, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
heart, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
blood vessel, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
blood vessel, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
brain, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
peripheral nervous system, pituitary gland, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
spinal cord, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
adrenal gland, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
parathyroid gland, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
skin, pinna, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
skin, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
oviduct, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
lung, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
trachea, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
eye, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
skin, pinna, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
lower urinary tract, urinary bladder, HET, Male, WTSI
Grb2tm1a(EUCOMM)Wtsi
kidney, HET, Female, WTSI
No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images
Grb2tm1a(EUCOMM)Wtsi
body, WT, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
head, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
head, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
body, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
head, HET, Female, WTSI

View all 244 images

Grb2tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Grb2tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Grb2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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